To Evaluate the Safety, Tolerability and Pharmacokinetics of K0706 in Plasma and Cerebrospinal Fluid in Healthy Volunteers
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Layout table for eligibility information
Ages Eligible for Study:
18 Years to 45 Years (Adult)
Sexes Eligible for Study:
Gender Based Eligibility:
Accepts Healthy Volunteers:
Healthy adult male subjects, 18 to 45 years of age, inclusive, at screening.
Willing and able to give written, and dated an informed consent.
Willing and able to comply with the scheduled visits, treatment plan, laboratory testing, study procedures, and restrictions in the Investigator's opinion, and be accessible for follow-up.
Medically healthy on the basis of medical history and physical examination.
Subjects enrolled in the study should not father a child and follow the necessary precautionary measure to be taken during the course of the study.
Subjects with a history of a frequent headache, nausea, or vomiting suggestive of increased intracranial pressure.
Subject report of recent (6-month) alcohol abuse or illicit drug use or who tests positive at screening, Check-in, or outpatient Visits for breath alcohol and/or drugs of abuse or cotinine;
Subjects with a history of any relevant allergy/hypersensitivity.
Subjects determined by the investigator to have any medical condition that could jeopardize their health or prejudice the results.
Subjects who have participated in CSF collection studies within 56 days prior to check-in.
Subjects who donated plasma within 14 days prior to the check-in visit.