Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients
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ClinicalTrials.gov Identifier: NCT03170245 |
Recruitment Status :
Recruiting
First Posted : May 31, 2017
Last Update Posted : May 11, 2020
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Condition or disease | Intervention/treatment |
---|---|
Thalassemia | Diagnostic Test: Interleukin-6 Diagnostic Test: HsC-RP Diagnostic Test: Adiponectin level Diagnostic Test: Carotid intima media thickness |

Study Type : | Observational |
Estimated Enrollment : | 80 participants |
Observational Model: | Case-Control |
Time Perspective: | Prospective |
Official Title: | Adiponectin, Interleukin-6 (IL-6) and High Sensitive C-reactive Protein (hsC-RP) in Relation to Carotid Intima-media Thickness in B-thalassemia Patients |
Actual Study Start Date : | August 1, 2018 |
Estimated Primary Completion Date : | July 30, 2020 |
Estimated Study Completion Date : | October 2020 |

Group/Cohort | Intervention/treatment |
---|---|
B thalassemia group
Laboratory investigations :
Imaging :
|
Diagnostic Test: Interleukin-6
serum samples used for doing the test by ELISA Diagnostic Test: HsC-RP serum samples used for doing the test by ELISA Diagnostic Test: Adiponectin level serum samples used for doing the test by ELISA Diagnostic Test: Carotid intima media thickness Done by carotid doppler |
Control group
Laboratory investigations :
Imaging :
|
Diagnostic Test: Interleukin-6
serum samples used for doing the test by ELISA Diagnostic Test: HsC-RP serum samples used for doing the test by ELISA Diagnostic Test: Adiponectin level serum samples used for doing the test by ELISA Diagnostic Test: Carotid intima media thickness Done by carotid doppler |
- Adiponectin [ Time Frame: once (1 day) ]Estimated by ElISA
- HsC-reactive protein [ Time Frame: once (1 day) ]By ELISA
- Interleukin-6 [ Time Frame: once (1 day) ]By ELISA
- carotid intima media thickness [ Time Frame: once (1 day) ]By carotid doppler
Biospecimen Retention: Samples Without DNA

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Ages Eligible for Study: | 16 Years and older (Child, Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Probability Sample |
Inclusion Criteria:
- B thalassemia patients
Exclusion Criteria:
- Diabetes mellitus
- Hypertension
- Obesity

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03170245
Contact: Osama A Ibraheim, MD | 00201006372498 | oibrahiem@yahoo.com | |
Contact: Walaa H Mohammed, MD | 00201005220944 | walaa.hosny2012@gmail.com |
Egypt | |
Assiut University Hospital | Recruiting |
Assiut, Egypt, Assiut university 71515 |
Responsible Party: | Asmaa Nady Hussein, Principal investigator, Assiut University |
ClinicalTrials.gov Identifier: | NCT03170245 |
Other Study ID Numbers: |
ADICIBT |
First Posted: | May 31, 2017 Key Record Dates |
Last Update Posted: | May 11, 2020 |
Last Verified: | May 2020 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | No |
Studies a U.S. FDA-regulated Drug Product: | No |
Studies a U.S. FDA-regulated Device Product: | No |
Thalassemia beta-Thalassemia Anemia, Hemolytic, Congenital Anemia, Hemolytic |
Anemia Hematologic Diseases Hemoglobinopathies Genetic Diseases, Inborn |