Global Congestive Heart Failure Registry (G-CHF)
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|ClinicalTrials.gov Identifier: NCT03078166|
Recruitment Status : Active, not recruiting
First Posted : March 13, 2017
Last Update Posted : July 28, 2020
|Condition or disease|
The G-CHF Registry is a prospective global cohort study of approximately 20,000-25,000 HF patients enrolled over approximately 5 years. Baseline data will be obtained on demographic and socioeconomic data, clinical and laboratory variables, co-morbidities, biomarkers, echocardiography, HF causes, medication use, management patterns, quality of life, and health systems. Six-month, 12-month, 18-month and 24-month follow-up data will be obtained to document patient outcomes and factors associated with outcomes.
A sub-study of approximately 4000 patients (a subset of the main study population) will be performed to measure frailty, cognitive and lung function, mental health, medication adherence, patient-reported barriers to care, dietary assessment, and collection of blood and urine samples for central storage and analysis.
|Study Type :||Observational [Patient Registry]|
|Estimated Enrollment :||25000 participants|
|Target Follow-Up Duration:||2 Years|
|Official Title:||Global Congestive Heart Failure Registry|
|Actual Study Start Date :||December 20, 2016|
|Estimated Primary Completion Date :||December 31, 2023|
|Estimated Study Completion Date :||December 31, 2023|
- Mortality, by cause [ Time Frame: 2 years ]The main objective of G-CHF is to obtain reliable estimates of mortality and other non-fatal clinical outcomes in HF patients overall and in 6 global regions. Factors associated with outcomes will be explored. All outcome events will be recorded and summarized individually as rates and proportions, with two-sided confidence intervals calculated.
- Non-fatal major clinical events (both resulting in and not resulting in hospitalization) [ Time Frame: 2 years ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03078166
|Hamilton General Hospital|
|Hamilton, Ontario, Canada, L8L2X2|
|Principal Investigator:||Salim Yusuf, DPhil, FRCPC, FRSC, O.C.||Executive Director|
|Principal Investigator:||Hisham Dokainish, M.D., FRCPC, FASE, FACC||Internal PHRI Lead Investigator|