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Comparative Efficacy of Dental Flossing Before or After Tooth Brushing on Interproximal Plaque Reduction and Fluoride Retention in That Area

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02971514
Recruitment Status : Completed
First Posted : November 23, 2016
Last Update Posted : November 23, 2016
Information provided by (Responsible Party):
Fatemeh Mazhari, Mashhad University of Medical Sciences

Brief Summary:
This randomized controlled crossover trial conducted on 25 dental students. in the preliminary session each volunteer was given a toothbrush(Trisa, soft, Switzerland) and toothpaste(Pooneh, Iran) and Dental Floss( Mina, Iran)to use during the study, and they were instructed the proper techniques of brushing and flossing.The study was performed in two treatment sessions and a 48 hour washout period. They passed through the sessions in a randomized sequence. After prophylaxis with rubber cup, they were asked to discontinue all oral hygiene for 24 hour. At the first session , they flossed first followed by brushing (floss-brush group) and at the other session they used dental floss after brushing (brush-floss group) . At each session, before and after brushing and flossing , Dental plaque reduction was assessed using Rustogi Modified Navi Plaque Index. Interdental plaque was collected for measuring fluoride. Differences between the two groups were analyzed with mixed model test.

Condition or disease Intervention/treatment Phase
Dental Devices, Home Care Behavioral: Flossing before Brushing Behavioral: Brushing before Flossing Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 25 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Triple (Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Supportive Care
Study Start Date : May 2014
Actual Primary Completion Date : April 2015

Arm Intervention/treatment
Experimental: Floss-Brush group
The participants flossed first followed by brushing
Behavioral: Flossing before Brushing
Active Comparator: Brush-Floss group
They used dental floss after brushing
Behavioral: Brushing before Flossing

Primary Outcome Measures :
  1. Dental plaque reduction [ Time Frame: immediately Before brushing/ flossing and immediately after these procedures ]
    Dental plaque assessed using a scale known as: "Rustogi Modified Navy Plaque Index"

Secondary Outcome Measures :
  1. fluoride concentration in Interdental plaque [ Time Frame: Immediately after toothbrushing /flossing interdental plaque was collected for fluoride measurement ]
    fluoride concentration measured using ppm scale (microgram/milliliter)

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 25 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Dental students with 16 teeth in each jaw who had Normal salivary volume No active caries No medicine which could be affect salivary secretion No fluoride consumption in the last two weeks No Antibiotic consumption in the last 4 weeks

Exclusion Criteria:

  • Any systemic diseases Periodontal diseases Crowding

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT02971514

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Iran, Islamic Republic of
Amir Moeintaghavi
Mashhad, Khorasan Razavi, Iran, Islamic Republic of, 91735-984
Sponsors and Collaborators
Mashhad University of Medical Sciences
Publications automatically indexed to this study by Identifier (NCT Number):
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Responsible Party: Fatemeh Mazhari, Associate professor od Pedodontics, Mashhad University of Medical Sciences Identifier: NCT02971514    
Other Study ID Numbers: 920200
First Posted: November 23, 2016    Key Record Dates
Last Update Posted: November 23, 2016
Last Verified: November 2016