Myopia Control With the Multi-segment Lens
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ClinicalTrials.gov Identifier: NCT02206217 |
Recruitment Status :
Completed
First Posted : August 1, 2014
Results First Posted : July 31, 2019
Last Update Posted : July 2, 2020
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The purpose of this study is to determine if the Multiple-Segment (MS) spectacle lens can slow myopia progression in Hong Kong schoolchildren.
MS lens is also called Defocus Incorporated Multiple Segments (DIMS) spectacle lens
Condition or disease | Intervention/treatment | Phase |
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Myopia | Device: Multiple-Segment spectacle lens | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 183 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Double (Participant, Outcomes Assessor) |
Primary Purpose: | Treatment |
Official Title: | The Clinical Trial of Myopia Control in Schoolchildren Using the Multi-segment (MS) Lens |
Actual Study Start Date : | August 2014 |
Actual Primary Completion Date : | July 2017 |
Actual Study Completion Date : | July 2017 |

Arm | Intervention/treatment |
---|---|
No Intervention: Single vision spectacle lens
Single vision lens with power for correcting distance refraction.
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Experimental: Multiple-Segment spectacle lens
A multifocal spectacle lens that corrects distance refraction and provides myopic defocus at the same time.
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Device: Multiple-Segment spectacle lens
A multifocal spectacle lens that corrects distance refraction and provides myopic defocus images simultaneously. The myopic defocus aims at slowing down myopia progression.
Other Name: MS lens |
- Cycloplegic Refraction Change in SER [ Time Frame: Baseline and 2 years ]Change in cycloplegic SER (in diopter) that was measured using Shin-Nippon NVision-K 5001 autorefractor.
- Axial Length [ Time Frame: Baseline and 2 years ]Axial length (mm) was measured after cycloplegia using IOL Master

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Ages Eligible for Study: | 8 Years to 13 Years (Child) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Age at enrolment: 8-13 year
- Spherical equivalent refractions (SER): -1.00 to -5.00 Dioptres (D)
- Astigmatism and anisometropia of 1.50 D or less
- Spectacle corrected monocular logMAR visual acuity: 0 or better
- Parents' understanding and acceptance of random allocation of grouping
Exclusion Criteria:
- any ocular and systemic abnormalities might affect visual functions or refractive development
- prior treatment of myopic control, e.g. drugs, orthokeratology, progressive addition lenses, bifocal lenses, drugs (e.g. atropine), etc.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02206217
China | |
Centre for Myopia Research, The Hong Kong Polytechnic University | |
Hong Kong, China | |
Hong Kong | |
Centre for Myopia Research, The Hong Kong Polytechnic University | |
Hong Kong, Hong Kong |
Principal Investigator: | Carly SY Lam, PhD | The Hong Kong Polytechnic University | |
Principal Investigator: | Chi ho To, PhD | The Hong Kong Polytechnic University |
Documents provided by Carly Lam, The Hong Kong Polytechnic University:
Responsible Party: | Carly Lam, Professor, The Hong Kong Polytechnic University |
ClinicalTrials.gov Identifier: | NCT02206217 |
Other Study ID Numbers: |
H-ZG3B |
First Posted: | August 1, 2014 Key Record Dates |
Results First Posted: | July 31, 2019 |
Last Update Posted: | July 2, 2020 |
Last Verified: | June 2020 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | No |
Myopia Refractive Errors Eye Diseases |