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Pilot Study,Diode Laser 808 nm Supported Direct Pulp Capping in Permanent Teeth (Laser in DPC)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01907919
Recruitment Status : Completed
First Posted : July 25, 2013
Last Update Posted : July 25, 2013
RWTH Aachen University
Information provided by (Responsible Party):
iraj yazdanfar, Yazdanfar, Iraj, M.D.

Brief Summary:
The purpose of this study was to compare the conventional and diode 808 nm laser-assisted techniques in direct pulp capping in permanent teeth .The present study was based on a series of ten clinical studies with pulp exposure caused by carious lesions.The hypothesis of this paper was laser supported direct pulp cap-ping has proven effectiveness by its capacity to stimulate reparative dentine formation by pulp cells, de-contamination ability of irradiated areas, its ability in the fast and better haemostatic, and pain reduction.

Condition or disease
Haemostatic Bacterial De-contamination Bio-stimulation Reparative Dentine Formation Pain Reduction

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Study Type : Observational [Patient Registry]
Actual Enrollment : 10 participants
Observational Model: Case Control
Time Perspective: Prospective
Target Follow-Up Duration: 12 Months
Official Title: Diode Laser-Assisted Direct Pulp Capping In Permanent Teeth
Study Start Date : July 2011
Actual Primary Completion Date : August 2012

conventional group,RM-GIC
1. Group A: Five teeth were treated with traditional rotating instruments, the cavities were prepared with diamond drills by turbine, multiple-blade drills by headpiece for removing the decayed dentine and, after cleaning and control of bleeding with cotton pellets with saline solution,RM-GIC (3M ESPE, USA) light-hardening paste was placed gently on the exposed part of the pulp and cavity floor next final restoration with composite z350 flow able and p60 (3M ESPE, USA).
Diode 808 nm laser-assisted group

2. Group B : Five teeth cavities were prepared as the same with group one with traditional rotating instruments, hemostatic and cavities sterilization were achieved by a diode 808 nm (Picasso- AMD, USA) laser using following parameters:

  • Hemostatic: 1.5 W, CW, fiber diameter 400µm, in contact, 2s per 1mm, vertical and horizontal scanning movement on exposure site.
  • Cavity sterilization: 1W, CW, fiber diameter 400µm, in contact, 2mm per s, circular movement.

After hemostatic and cavity sterilization, RM-GIC (3M ESPE, USA) light-hardening paste was placed on the exposed part of the pulp and cavity floor next final restoration with composite z350 flow able and p60 (3M ESPE, USA).

Primary Outcome Measures :
  1. Maintenance of teeth vitality was be measured via thermal tests also by radiographic. [ Time Frame: up to 12 months ]
    Given low success rate of conventional methods, new techniques as laser-assisted need to be developed.The outcome measure of this study was maintenance of teeth vitality with carious exposed via tertiary dentine formation.the tertiary dentine formation during the time of study was assessed radiological. Therefore vitality of the teeth was depend on dentine formation that was measured periodically in 1,6 and 12 months.

Information from the National Library of Medicine

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Ages Eligible for Study:   12 Years to 40 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
This study was carried out on 10 patients, aged between 12 and 40 years, with an average age of 26 years, who underwent conservative treatment for deep caries of permanent teeth (2 anterior and 8 posterior).

Inclusion Criteria:

  1. Permanent teeth with deep caries
  2. Vitality of teeth
  3. No peri-apical radiographic changes
  4. Acceptance research program

Exclusion Criteria:

  1. Symptoms
  2. Peri-apical radiographic changes
  3. No stopped bleeding within 3 minutes after exposure
  4. No acceptance study program
Additional Information:

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Responsible Party: iraj yazdanfar, M.Sc in laser in dentistry, Yazdanfar, Iraj, M.D. Identifier: NCT01907919    
Other Study ID Numbers: private practice
First Posted: July 25, 2013    Key Record Dates
Last Update Posted: July 25, 2013
Last Verified: July 2013
Keywords provided by iraj yazdanfar, Yazdanfar, Iraj, M.D.:
Pulp capping, Diode laser 808 nm, Tertiary dentin, RM-GIC
Additional relevant MeSH terms:
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Dentin, Secondary
Dental Pulp Diseases
Tooth Diseases
Stomatognathic Diseases