The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Study
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT01864031 |
Recruitment Status : Unknown
Verified May 2013 by Harry Hemingway, University College, London.
Recruitment status was: Active, not recruiting
First Posted : May 29, 2013
Last Update Posted : May 29, 2013
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease |
---|
Chronic Stable Angina Unstable Angina Coronary Heart Disease Not Otherwise Specified Acute Myocardial Infarction Heart Failure Ventricular Arrhythmias Cardiac Arrest Abdominal Aortic Aneurysm Peripheral Arterial Disease Ischaemic Stroke Subarachnoid Haemorrhagic Stroke Intracerebral Haemorrhagic Stroke Stroke Not Otherwise Specified Sudden Cardiac Death Unheralded Coronary Death Mortality Coronary Heart Disease (CHD) Cardiovascular Disease (CVD) Fatal Cardiovascular Disease (Fatal CVD) ST Elevation Myocardial Infarction (STEMI) Non-ST Elevation Myocardial Infarction (nSTEMI) Myocardial Infarction Not Otherwise Specified (MI NOS) |

Study Type : | Observational |
Actual Enrollment : | 2240000 participants |
Observational Model: | Cohort |
Time Perspective: | Prospective |
Official Title: | The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Study Using Linked Electronic Health Records |
Study Start Date : | January 1997 |
Estimated Primary Completion Date : | December 2013 |
Estimated Study Completion Date : | December 2014 |
- Initial presentation of cardiovascular disease [ Time Frame: Study follow-up will commence on the earliest date that a patient fulfils the study inclusion criteria during the period between 1st January 1997 and 25th March 2010 (maximum of 13 years follow-up) ]See "Conditions" and "Detailed Description" sections for further description of the endpoints used.
- Non-CVD mortality [ Time Frame: Same as for primary outcomes (maximum of 13 years follow-up) ]Death from non-CVD causes.

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 30 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- Aged ≥ 30 years.
- Patient in a GPRD registered practice that has consented to the linkage process (who also met data quality standards).
Exclusion Criteria:
- A recorded history of any cardiovascular disease phenotype prior to entering the study.
- Cause of death unknown.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01864031
United Kingdom | |
University College London | |
London, United Kingdom |
Principal Investigator: | Steven Bell, PhD | University College, London | |
Study Director: | Harry Hemingway, FRCP | University College, London |
Publications:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | Harry Hemingway, Professor of Clinical Epidemiology, University College, London |
ClinicalTrials.gov Identifier: | NCT01864031 |
Other Study ID Numbers: |
CALIBER 12-02 086091/Z/08/Z ( Other Grant/Funding Number: Wellcome Trust ) RP-PG-0407-10314 ( Other Grant/Funding Number: National Institute for Health Research (NIHR) ) |
First Posted: | May 29, 2013 Key Record Dates |
Last Update Posted: | May 29, 2013 |
Last Verified: | May 2013 |
Alcohol Drinking Abstainers Former drinkers Ex-drinkers Aetiology Initial presentation Chronic Stable Angina Unstable Angina Coronary Heart Disease Not Otherwise Specified Acute Myocardial Infarction Heart Failure ST elevation Myocardial Infarction (STEMI) non-ST elevation Myocardial Infarction (nSTEMI) Myocardial Infarction Not Otherwise Specified (MI NOS) |
Ventricular Arrhythmias Cardiac Arrest Abdominal Aortic Aneurysm Peripheral Arterial Disease Ischaemic Stroke Subarachnoid Haemorrhagic Stroke Intracerebral haemorrhagic Stroke Stroke Not Otherwise Specified Sudden Cardiac Death Unheralded Coronary Death Mortality Coronary Heart Disease (CHD) Cardiovascular Disease (CVD) Fatal Cardiovascular Disease (fatal CVD) |
Stroke Intracranial Hemorrhages Heart Failure Cardiovascular Diseases Myocardial Infarction Heart Diseases Aneurysm Heart Arrest Angina Pectoris Arrhythmias, Cardiac Aortic Aneurysm Coronary Disease Coronary Artery Disease Myocardial Ischemia Peripheral Arterial Disease |
Peripheral Vascular Diseases Aortic Aneurysm, Abdominal ST Elevation Myocardial Infarction Angina, Stable Death, Sudden, Cardiac Angina, Unstable Non-ST Elevated Myocardial Infarction Infarction Death Alcohol Drinking Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Vascular Diseases |