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Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbation if COPD?

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ClinicalTrials.gov Identifier: NCT01507415
Recruitment Status : Completed
First Posted : January 10, 2012
Last Update Posted : November 5, 2014
Sponsor:
Collaborators:
Medical Research Council
The Hillingdon Hospitals NHS Foundation Trust
West Hertfordshire Hospitals NHS Trust
Information provided by (Responsible Party):
Royal Brompton & Harefield NHS Foundation Trust

Study Description
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Brief Summary:

This study aims to evaluate simple tests of physical function in hospitalised patients with chronic obstructive pulmonary disease (COPD) and to assess whether they can predict future hospital readmission. The Short Physical Performance Battery (SPPB) is a simple test of standing balance, usual walking speed (4-metre gait speed) and ability to stand from a chair, which reflects global physical functioning and frailty.

We hypothesise that the SPPB or 4-metre gait speed can predict future hospital readmissions.


Condition or disease
Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases Lung Diseases Lung Diseases, Obstructive Bronchitis, Chronic Pulmonary Emphysema Disease Progression

Study Design
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Study Type : Observational
Actual Enrollment : 226 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbation if COPD?
Study Start Date : November 2011
Actual Primary Completion Date : February 2013
Actual Study Completion Date : February 2014

Resource links provided by the National Library of Medicine


Groups and Cohorts
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Group/Cohort
Exacerbation
Patients with Chronic Obstructive Pulmonary Disease (COPD)


Outcome Measures
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Primary Outcome Measures :
  1. Hospital readmission rate [ Time Frame: 3 months ]

Secondary Outcome Measures :
  1. Hospital readmission rate [ Time Frame: 12 months ]
  2. Time to first hospital readmission [ Time Frame: 12 months ]
  3. Hospital Bed days [ Time Frame: 12 months ]

Biospecimen Retention:   Samples With DNA
Whole blood, plasma and serum.

Eligibility Criteria
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Ages Eligible for Study:   35 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Any patient hospitalised with an acute exacerbation of COPD. Cohorts will be recruited from local District General Hospitals with Acute Admissions Units and Accident & Emergency Departments.
Criteria

Inclusion Criteria:

  • Hospital admission with an exacerbation of COPD
  • Must have capacity to consent
  • Able to walk

Exclusion Criteria:

  • Co-morbibities that limit walking ability
  • Co-morbidities that make walking unsafe
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01507415


Locations
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United Kingdom
Hillingdon Hospital
Uxbridge, United Kingdom, UB8 3NN
Watford General Hospital
Watford, United Kingdom, WD18 0HB
Sponsors and Collaborators
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council
The Hillingdon Hospitals NHS Foundation Trust
West Hertfordshire Hospitals NHS Trust
Investigators
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Principal Investigator: William DC Man, MRCP PhD NIHR Respiratory Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust
More Information
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Publications:

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

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Responsible Party: Royal Brompton & Harefield NHS Foundation Trust
ClinicalTrials.gov Identifier: NCT01507415    
Other Study ID Numbers: 2011LF015H
First Posted: January 10, 2012    Key Record Dates
Last Update Posted: November 5, 2014
Last Verified: November 2014
Keywords provided by Royal Brompton & Harefield NHS Foundation Trust:
Cohort Studies
Longitudinal Studies
Patient Readmission
Hospitalization
Disability Evaluation
Additional relevant MeSH terms:
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Bronchitis
Bronchitis, Chronic
Lung Diseases
Pulmonary Disease, Chronic Obstructive
Pulmonary Emphysema
Respiratory Tract Diseases
Lung Diseases, Obstructive
 Disease Progression
Emphysema
Disease Attributes
Pathologic Processes
Respiratory Tract Infections
Infections
Bronchial Diseases