Working… Menu

Genetic Assessment of the Patients With Metabolic Syndrome (GENMetS)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01268696
Recruitment Status : Unknown
Verified December 2010 by Medical Universtity of Lodz.
Recruitment status was:  Active, not recruiting
First Posted : December 31, 2010
Last Update Posted : July 22, 2011
Information provided by:
Medical Universtity of Lodz

Brief Summary:

Metabolic syndrome is a combination of medical disorders that increase the risk of developing cardiovascular disease and diabetes. The exact mechanisms of the complex pathways of metabolic syndrome are not yet completely known. The pathophysiology is extremely complex and has been only partially elucidated. Most patients are older, obese, sedentary, and have a degree of insulin resistance. Stress can also be a contributing factor. The most important factors are:

weight, genetics, aging, sedentary lifestyle,excess caloric intake. In our study we will assess the role of some polymorphisms in the pathology of metabolic syndrome.

Condition or disease
Metabolic Syndrome

Detailed Description:

Eligibility criteria to the study:

  • patients with metabolic syndrome
  • with written consent

Layout table for study information
Study Type : Observational
Estimated Enrollment : 300 participants
Observational Model: Case-Control
Time Perspective: Prospective
Official Title: Genetic Assessment of the Patients With Metabolic Syndrome in Polish Population
Study Start Date : December 2010
Estimated Primary Completion Date : August 2011
Estimated Study Completion Date : January 2015

Resource links provided by the National Library of Medicine

control group
healthy volunteers
Metabolic group
Patients with metabolic syndrome

Biospecimen Retention:   Samples With DNA
the blood samples taken into EDTA

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Patients with metabolic syndrome

Inclusion Criteria:

  • patients with metabolic syndrome according to IDF,AHA and NHLBI 2009

Exclusion Criteria:

  • diabetes type 1
  • cancer
  • not consent
  • steroid therapy
  • alcohol or drug abuse
  • chronic inflammatory disease
  • pregnancy or lactation
  • severe hypothyroidism
  • immunosuppressive treatment
  • operation or severe injury during the last month

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01268696

Layout table for location information
Department of medical biotechnology Medical University of Lodz
Lodz, Poland
Sponsors and Collaborators
Medical Universtity of Lodz
Layout table for investigator information
Study Chair: Tadeusz Pietrucha, prof. Department of medical biotechnology
Layout table for additonal information
Responsible Party: Department of Medical Biotechnology, Medical University of Lodz Identifier: NCT01268696    
Other Study ID Numbers: RNN/202/10/KE
First Posted: December 31, 2010    Key Record Dates
Last Update Posted: July 22, 2011
Last Verified: December 2010
Keywords provided by Medical Universtity of Lodz:
Additional relevant MeSH terms:
Layout table for MeSH terms
Metabolic Syndrome
Pathologic Processes
Insulin Resistance
Glucose Metabolism Disorders
Metabolic Diseases