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ClinicalTrials.gov Identifier: NCT01255540
Recruitment Status : Unknown
Verified October 2015 by Oslo University Hospital. Recruitment status was: Active, not recruiting
The rationale of the present clinical trial is to study whether an invasive strategy in clinical stable patients over 80 years with NSTEMI/UAP may improve rates of death, reinfarction, stroke, need of urgent revascularisation, myocardial function and quality of life. The invasive approach involves coronary angiography with immediate evaluation for three different treatment options; 1. Percutaneous coronary intervention (PCI), 2. Coronary artery bypass graft (CABG) or 3. medical treatment. Clinical practice shows that older patients are commonly treated less vigorously than younger patients and the present guidelines are based on a considerably younger population.
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Layout table for eligibility information
Ages Eligible for Study:
80 Years and older (Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Age ≥ 80 years.
Acute coronary syndrome (NSTEMI/UAP) with chest pain > 10 minutes, with or without ST-segment depression in ECG, and normal or elevated levels of troponin T or I. Elevated troponin levels are defined as values exceeding the 99 percentile of a normal population at the local laboratory at each participating site.
Age < 80 years.
ST-segment elevation in ECG (STEMI)
Clinical unstable with ongoing chest pain or other ischaemic symptoms/signs.
Short life expectancy due to extra cardiac reason, ie. COPD, disseminated malignant disease, or other reason.
Anamnestic indications for significant mental disorder, including dementia.
Any condition which interferes with patients possibility to comply with protocol.