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Invasive Infections in Children With Hemoglobinopathies

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ClinicalTrials.gov Identifier: NCT00456443
Recruitment Status : Completed
First Posted : April 5, 2007
Last Update Posted : April 5, 2007
Information provided by:
HaEmek Medical Center, Israel

Brief Summary:
Patients diagnosed as having hemoglobinopathies are exposed to serious bacterial infections, principally those patients that underwent splenectomy. Since the introduction of anti pneumococcal vaccine the incidence decreased significantly but other bacteria besides encapsulated bacteria takes place as principal cause of invasive infections. The purpose of this study is to analyse in a retrospective study the incidence of those infections in a group of patients suffering from thalassemia and sickle cell anemia treated in our clinic.

Condition or disease Intervention/treatment
Thalassemia Sickle Cell Anemia Procedure: Historical records

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Study Type : Observational
Enrollment : 200 participants
Observational Model: Defined Population
Time Perspective: Other
Official Title: Invasive Infections in Children With Hemoglobinopathies. A Clinical Descriptive Retrospective Study.
Study Start Date : January 2006
Actual Study Completion Date : June 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Thalassemia

Information from the National Library of Medicine

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Ages Eligible for Study:   up to 40 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • All patients treated in the Pediatric Hematology Unit.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00456443

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Pediatric Hematology Unit and Pediatric Dpt B - HaEmek Medical Center
Afula, Israel, 18101
Sponsors and Collaborators
HaEmek Medical Center, Israel
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Study Director: Ariel Koren, MD Pediatric Hematology Unit, Ha'Emek Medical Center
Principal Investigator: Waheeb Sakran, MD Pediatric Dpt B - Ha'Emek Medical Center
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ClinicalTrials.gov Identifier: NCT00456443    
Other Study ID Numbers: 4140905.EMC
First Posted: April 5, 2007    Key Record Dates
Last Update Posted: April 5, 2007
Last Verified: April 2007
Keywords provided by HaEmek Medical Center, Israel:
Sickle cell anemia
Streptococcal Pneumonia
Additional relevant MeSH terms:
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Anemia, Sickle Cell
Hematologic Diseases
Anemia, Hemolytic, Congenital
Anemia, Hemolytic
Genetic Diseases, Inborn