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Massage Therapy for Osteoarthritis of the Knee

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00322244
Recruitment Status : Completed
First Posted : May 5, 2006
Last Update Posted : February 1, 2011
Yale University
Information provided by:
Rutgers, The State University of New Jersey

Brief Summary:

The study is a randomized, controlled clinical trial that investigates the efficacy ogf massage therapy for 66 patients with pain secondary to osteoarthritis of the knee. It is a wait-list design where subjects and randomly assigned to either Group A or Group B. Group A receives two months of massage while Group B is wait-listed, receives two months of usual care. At the conclusion of the wait period, Group B receives two months of massage. In all cases, subjects continue to receive conventional medical care for their OA symptoms.

Outcome measures include a WOMAC questionnaire, a visual analog pain scale, time to walk fifty feet and range of motion of the knee (using a goniometer). A research assistant, competent in appropriate subject assessment obtains the outcome measures. Change in medication use is tracked by the use of patient diaries. Assessments of subjects, occurs at baseline, and week 8 and 16 in both the intervention and control groups.

Condition or disease Intervention/treatment Phase
Osteoarthritis Procedure: Massage Therapy Not Applicable

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Study Type : Interventional  (Clinical Trial)
Enrollment : 66 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: Massage Therapy for Osteoarthritis of the Knee
Study Start Date : January 2003
Study Completion Date : October 2003

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Osteoarthritis

Primary Outcome Measures :
  1. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain and functional scores
  2. Visual Analog Scale (VAS)

Secondary Outcome Measures :
  1. Range of motion
  2. Time to walk 50 feet

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   35 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Radiographically confirmed diagnosis of osteoarthritis
  • 35 years of age or greater
  • pre-randomization VAS score between 4 and 9

Exclusion Criteria:

  • Rheumatoid, arthritis, fibromyalgia, recurrent or active pseudo-gout, cancer or other serious medical condition
  • History of kidney or liver failure
  • Asthma requiring steroids
  • oral steroids within the last four weeks
  • Intra-articular knee depo-corticosteroids within the previous 3 months
  • Intra-articular hyaluronate within the previous 6 months
  • Arthroscopy of the knee within the previous year
  • Significant injury to the knee within the previous 6 months
  • rash or open wound over the knee

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00322244

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United States, New Jersey
Saint Barnabas Ambulatory Care Center
Livingston, New Jersey, United States, 07039
Sponsors and Collaborators
University of Medicine and Dentistry of New Jersey
Yale University
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Principal Investigator: Adam I. Perlman, MD, MPH University of Medicine and Dentistry of New Jersey
Publications automatically indexed to this study by Identifier (NCT Number):
Layout table for additonal information Identifier: NCT00322244    
Other Study ID Numbers: 0120020367
CORPRC #U48-CCU115802
First Posted: May 5, 2006    Key Record Dates
Last Update Posted: February 1, 2011
Last Verified: January 2011
Keywords provided by Rutgers, The State University of New Jersey:
Massage therapy
Additional relevant MeSH terms:
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Osteoarthritis, Knee
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases