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Case Notes Review on Patients With Hereditary Haemorrhagic Telangiectasia

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ClinicalTrials.gov Identifier: NCT00230685
Recruitment Status : Unknown
Verified August 2008 by Imperial College London.
Recruitment status was:  Recruiting
First Posted : October 3, 2005
Last Update Posted : May 29, 2015
The Margaret Hayton HHT Fund
Information provided by (Responsible Party):
Imperial College London

Brief Summary:
The Hammersmith Hospital provides a clinical service for patients with Hereditary haemorrhagic telangiectasia and pulmonary arteriovenous malformations that is unique in the United Kingdom. Measurements obtained as part of standard clinical practice that has evolved since 1985 allow us to assess whether particular groups of individuals that we see are more prone to recognised complications such as strokes, brain abscesses, pregnancy related complications or pulmonary hypertension. We hypothesise that certain clinical characteristics will predict the susceptibility of individuals to particular complications.

Condition or disease
Telangiectasia, Hereditary Hemorrhagic

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Study Type : Observational
Estimated Enrollment : 500 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Hammersmith Hospital Patients With Pulmonary Arteriovenous Malformations (PAVMs) and Hereditary Haemorrhagic Telangiectasia
Study Start Date : January 2000
Estimated Primary Completion Date : January 2018
Estimated Study Completion Date : January 2018

Primary Outcome Measures :
  1. Stroke [ Time Frame: Prospective ]
  2. Venous thromboemboli (VTE) [ Time Frame: Prospective ]

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients referred to the hereditary haemorrhagic telangiectasia clinical service at Hammersmith Hospital, imperial College Healthcare NHS Trust

Inclusion Criteria:

  • Patients attending Hammersmith Hospital

Exclusion Criteria:

  • None

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00230685

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Contact: Claire L Shovlin 0208 383 1000 c.shovlin@imperial.ac.uk

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United Kingdom
Respiratory Medicine, Hammersmith Hospital Recruiting
London, United Kingdom, W12 0NN
Contact: Claire L Shovlin       c.shovlin@imperial.ac.uk   
Principal Investigator: Claire L Shovlin         
Sponsors and Collaborators
Imperial College London
The Margaret Hayton HHT Fund
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Principal Investigator: Claire L Shovlin Imperial College London
Publications of Results:

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Responsible Party: Imperial College London
ClinicalTrials.gov Identifier: NCT00230685    
Other Study ID Numbers: IC/CLS2
First Posted: October 3, 2005    Key Record Dates
Last Update Posted: May 29, 2015
Last Verified: August 2008
Keywords provided by Imperial College London:
Pulmonary arteriovenous malformations
Additional relevant MeSH terms:
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Arteriovenous Malformations
Telangiectasia, Hereditary Hemorrhagic
Vascular Diseases
Cardiovascular Diseases
Vascular Malformations
Cardiovascular Abnormalities
Congenital Abnormalities
Hemostatic Disorders
Hemorrhagic Disorders
Hematologic Diseases