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Trial record 6 of 36 for:    stem cell peripheral arterial disease AND marrow

Novel Therapy of PAD by Combined Transplantation of BMCs

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00411840
Recruitment Status : Unknown
Verified December 2006 by Heinrich-Heine University, Duesseldorf.
Recruitment status was:  Recruiting
First Posted : December 15, 2006
Last Update Posted : December 15, 2006
Information provided by:
Heinrich-Heine University, Duesseldorf

Brief Summary:

We analyze the effects of combined intramuscular and intraarterial transplantation of BMCs in patients with PAD. BMCs were transplanted into the ischemic limb.

After 2 and 13 months walking distance and perfusion indices were monitored.

Condition or disease Intervention/treatment Phase
Peripheral Arterial Disease Procedure: intraarterial and intramuscular injection of BMCs Phase 1

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Study Type : Interventional  (Clinical Trial)
Enrollment : 100 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Transplantation of Autologous Mononuclear Bone Marrow Stem Cells in Patients With Peripheral Arterial Disease (TAM-PAD Study)
Study Start Date : July 2004

Resource links provided by the National Library of Medicine

Primary Outcome Measures :
  1. ABI, walking distance, capillary-venous oxygen saturation, venous occlusion plethysmography

Secondary Outcome Measures :
  1. feasibility

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • severe limb ischemia

Exclusion Criteria:

  • infectious disease
  • cancer

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00411840

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Contact: Thomas Bartsch, MD +492118118800

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Heinrich-Heine-University Recruiting
Duesseldorf, Germany, 40225
Contact: Bodo E Strauer, MD    +492118118801   
Principal Investigator: Thomas Bartsch, MD         
Sponsors and Collaborators
Heinrich-Heine University, Duesseldorf
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Study Director: Bodo E Strauer, MD Heinrich-Heine University, Duesseldorf
Layout table for additonal information Identifier: NCT00411840    
Other Study ID Numbers: TAM-PAD
First Posted: December 15, 2006    Key Record Dates
Last Update Posted: December 15, 2006
Last Verified: December 2006
Keywords provided by Heinrich-Heine University, Duesseldorf:
stem cell therapy
peripheral arterial disease
limb ischemia
Additional relevant MeSH terms:
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Peripheral Arterial Disease
Peripheral Vascular Diseases
Arterial Occlusive Diseases
Vascular Diseases
Cardiovascular Diseases