Cytomegalovirus (CMV) Infection in Pregnancy
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|ClinicalTrials.gov Identifier: NCT00194155|
Recruitment Status : Completed
First Posted : September 19, 2005
Last Update Posted : August 17, 2016
|Condition or disease|
|Pregnancy Complications Cytomegalovirus Infection|
CMV infection in adults with a normal immune system is rarely a serious event. Once a person has been infected with CMV, they may have recurrences (relapses) of the infection. If a mother is infected with the virus or relapses during pregnancy, her fetus may be at risk for infection. Unlike infection in adults, fetal infection may result in serious complications (congenital infection). The effects of fetal infection with CMV are well understood and many efforts have been made to potentially reduce the risk of congenital infection. However, the effect of CMV infection on the pregnancy itself (when the fetus is not affected by CMV) is less understood.
In this study, we plan to determine if CMV recurrence in the mother results in pregnancy complications. The pregnancy complications listed above have been associated with poor placental function. We also plan to determine if (recurrent) CMV infection in the mother is associated with CMV infection of the placenta.
|Study Type :||Observational|
|Actual Enrollment :||283 participants|
|Official Title:||Cytomegalovirus Infection and Pregnancy Outcomes|
|Study Start Date :||May 2003|
|Actual Primary Completion Date :||February 2008|
|Actual Study Completion Date :||February 2008|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00194155
|United States, Pennsylvania|
|Hospital of the University of Pennsylvania|
|Philadelphia, Pennsylvania, United States, 19104|
|Principal Investigator:||Samuel Parry, MD||University of Pennsylvania|