Passive Leg Raise Induced Stroke Volume Changes in Elderly Prior to Elective Surgery Measured by LiDCOplusTM
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|ClinicalTrials.gov Identifier: NCT02977390|
Recruitment Status : Completed
First Posted : November 30, 2016
Last Update Posted : December 1, 2016
|Condition or disease||Intervention/treatment||Phase|
|Stroke Volume Cardiovascular System Fluid Therapy||Other: Passive leg raise||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||10 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Passive Leg Raise Induced Stroke Volume Changes in Elderly Prior to Elective Surgery Measured by LiDCOplusTM to Guide Fluid Therapy|
|Study Start Date :||October 2013|
|Actual Primary Completion Date :||January 2015|
|Actual Study Completion Date :||January 2015|
Passive Leg Raise (PLR)
The patient is placed in a 45 degree recumbent position. Stroke volume is measured in ml.
Intervention:The patient is placed horizontal and the legs are passively raised to 45 degrees.
Measurement:The effect of the PLR on Stroke Volume is measured. Thereafter the patient is repositioned to the initial position and Stroke Volume is measured again.
Other: Passive leg raise
By tilting the patient's bed from sitting 45 degrees to supine with legs tilted up 45 degrees we recruit the blood volume in the legs and can measure a reversible fluid challenge on stroke volume.
- Assess passive leg raise responsiveness in spontaneously breathing aged patients. [ Time Frame: Within 1 minute of the intervention ]Stroke volume changes in ml and as per cent change compared to baseline
- Investigate whether there is an association between a positive response to passive leg raise on stroke volume and post spinal anesthesia. [ Time Frame: 30 minutes ]Post spinal bloodpressure per cent change or 30 mmHg decrease
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02977390
|Karolinska University Hospital|
|Huddinge, Sweden, 14186|
|Principal Investigator:||Sigridur Kalman, Professor||Karolinska Institutet|