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Effectiveness of Calcium Channel Blockers and Adenosine in the Emergency Management of SVT

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ClinicalTrials.gov Identifier: NCT00413712
Recruitment Status : Completed
First Posted : December 20, 2006
Last Update Posted : February 10, 2017
Sponsor:
Information provided by (Responsible Party):
Singapore General Hospital

Study Description
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Brief Summary:
The purpose of this study is to determine the efficacy and effectiveness of calcium channel blockers and adenosine in the treatment of Supraventricular Tachycardia.

Condition or disease Intervention/treatment Phase
Supraventricular Tachycardia Drug: Calcium Channel Blocker & Adenosine Phase 4

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Study Design
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Study Type : Interventional  (Clinical Trial)
Enrollment : 206 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Comparism Between Efficacy and Effectiveness Between Slow Infusion of Calcium Channel Blockers and Intravenous Bolus Adenosine in the Management of Supraventricular Tachycardia in the Emergency Department.
Study Start Date : January 1997
Study Completion Date : March 2001

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Calcium

Arms and Interventions
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Outcome Measures
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Primary Outcome Measures :
  1. Conversion to the sinus rhythm.

Secondary Outcome Measures :
  1. Recurrence of SVT
  2. Stability of vital signs

Eligibility Criteria
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Ages Eligible for Study:   10 Years and older   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • More than 10 years old
  • Electrocardiographic diagnosis of SVT
  • SVT not converted by the vagal manoeuvres

Exclusion Criteria:

  • Signs of impaired cerebral perfusion
  • Signs of pulmonary oedema
  • Subsequent diagnosis of other types of arrythmias rather than SVT
  • pregnancy by history
Contacts and Locations
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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00413712


Locations
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Singapore
Singapore General Hospital
Singapore, Singapore, 62223322
Sponsors and Collaborators
Singapore General Hospital
Investigators
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Principal Investigator: Lim S Han, MBBS,FRCS Department of Emergency Medicine, Singapore General Hospital
More Information
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Publications:

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Responsible Party: Singapore General Hospital
ClinicalTrials.gov Identifier: NCT00413712     History of Changes
Other Study ID Numbers: IRB18/1997
First Posted: December 20, 2006    Key Record Dates
Last Update Posted: February 10, 2017
Last Verified: February 2017

Keywords provided by Singapore General Hospital:
Supraventricular Tachycardia
Calcium Channel Blockers
Verapamil
Diltiazem
Adenosine

Additional relevant MeSH terms:
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Adenosine
Emergencies
Tachycardia
Tachycardia, Supraventricular
Disease Attributes
Pathologic Processes
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Cardiac Conduction System Disease
Calcium
Calcium, Dietary
Calcium Channel Blockers
Calcium-Regulating Hormones and Agents
 Physiological Effects of Drugs
Bone Density Conservation Agents
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
Anti-Arrhythmia Agents
Vasodilator Agents
Purinergic P1 Receptor Agonists
Purinergic Agonists
Purinergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Membrane Transport Modulators