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Trial record 55 of 116 for:    Atenolol

Health Assessment Study (0954-946)

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ClinicalTrials.gov Identifier: NCT00541684
Recruitment Status : Completed
First Posted : October 10, 2007
Last Update Posted : April 12, 2017
Sponsor:
Information provided by (Responsible Party):
Merck Sharp & Dohme Corp.

Brief Summary:
The study will look at the effects of losartan or atenolol on frequency of sexual intercourse in subjects with newly diagnosed mild to moderate hypertension.

Condition or disease Intervention/treatment Phase
Hypertension Drug: MK0954, /Duration of Treatment : 16 Weeks Drug: Comparator : atenolol /Duration of Treatment : 16 Weeks Phase 3

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 143 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: A Randomized, Double-Blind, Two Arm, Parallel Group Health Assessment Study of Losartan or Atenolol in Patients With Mild to Moderate Hypertension
Actual Study Start Date : July 11, 2001
Actual Primary Completion Date : January 23, 2003
Actual Study Completion Date : January 23, 2003

Resource links provided by the National Library of Medicine

Drug Information available for: Atenolol




Primary Outcome Measures :
  1. number of sexual intercourse events in a 2-week period [ Time Frame: 2 Weeks ]

Secondary Outcome Measures :
  1. sexual functioning score and overall sexual satisfaction score after 16 weeks [ Time Frame: 16 Weeks ]


Information from the National Library of Medicine

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Ages Eligible for Study:   40 Years to 49 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Newly diagnosed with mild to moderate hypertension\
  • Married male in stable heterosexual relationship
  • No prior history of sexual dysfunction
  • Satisfied with overall sex life
  • Patient's spouse is in close proximity for the study
  • Has had at least 2 but not more than 10 sexual intercourse events during the 2 week period prior to study start
  • Patient able to visit doctor in the morning of each scheduled visit
  • Able to complete the self administered health assessment questionnaire

Exclusion Criteria:

  • Hypertension due to cancer, history of heart or circulatory problems
  • History of mental disorder that might impair sexual function
  • History or presence of drug or alcohol abuse
  • Prior surgery for erectile dysfunction or other urological procedure
  • No penile implant or assist devices
  • History of chronic liver disease, history of diabetes
  • History of severe life-threatening diseases such as, cancer, AIDS or positive HIV test
  • Subjects with only 1 kidney
  • Mental handicap or legal incapacity

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00541684


Sponsors and Collaborators
Merck Sharp & Dohme Corp.
Investigators
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Study Director: Medical Monitor Merck Sharp & Dohme Corp.

Additional Information:
Study Data/Documents: CSR Synopsis  This link exits the ClinicalTrials.gov site

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Responsible Party: Merck Sharp & Dohme Corp.
ClinicalTrials.gov Identifier: NCT00541684     History of Changes
Other Study ID Numbers: 0954-946
2007_624
First Posted: October 10, 2007    Key Record Dates
Last Update Posted: April 12, 2017
Last Verified: April 2017
Additional relevant MeSH terms:
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Atenolol
Hypertension
Vascular Diseases
Cardiovascular Diseases
Adrenergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs
Autonomic Agents
Peripheral Nervous System Agents
Anti-Arrhythmia Agents
Antihypertensive Agents
Sympatholytics
Adrenergic beta-1 Receptor Antagonists
Adrenergic beta-Antagonists
Adrenergic Antagonists