Exploratory Study of Raised Serum Lactate as a Marker of Necrotizing Fasciitis
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|ClinicalTrials.gov Identifier: NCT01739959|
Recruitment Status : Completed
First Posted : December 4, 2012
Last Update Posted : December 4, 2012
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||53 participants|
|Official Title:||Raised Serum Lactate as a Marker of Necrotizing Fasciitis; a Consecutive Prospective Review.|
|Study Start Date :||September 2000|
|Actual Primary Completion Date :||September 2010|
|Actual Study Completion Date :||September 2010|
Necrotizing fasciitis proven
Histological evidence of necrotizing fasciitis at initial surgical debridement
Not necrotizing fasciitis
A composite of those with no histological tissue necrosis at initial surgical debridement, and those clinically judged not to be a necrotizing infection who therefore did not undergo surgery.
- Serum lactate level [ Time Frame: At referral to the Plastic Surgery Team ]Serum lactate level at initial referral to the plastic surgery team, as measured by arterial blood gas analysis (calibrated point-of-care testing). Levels compared between the group with confirmed histological necrosis at initial surgical debridement, versus those with no evidence of necrosis (a composite of those who did not undergo surgery as they were judged not to have necrotizing fasciitis, and those who did undergo surgery, but whose histology did not show tissue necrosis).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01739959
|Wexham Park Hospital|
|Slough, London, United Kingdom, SL2 4HL|
|Principal Investigator:||George Murphy, MRCS||Wexham Park Hospital|