LC-MS/MS 25(OH)D Status in a Large Cohort
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|ClinicalTrials.gov Identifier: NCT03388203|
Recruitment Status : Completed
First Posted : January 2, 2018
Last Update Posted : January 2, 2018
The present study assessed serum 25(OH)D in a cohort of 74235 outpatients by liquid-chromatography-tandem-mass-spectrometry (LC-MS/MS).
The investigators studied the distribution of serum 25(OH)D concentrations in males and females of different age groups, the prevalence of measurable amounts of 25(OH)D2 and seasonal variability.
|Condition or disease||Intervention/treatment|
|25(OH)D Measurement and 25(OH)D Deficiency||Diagnostic Test: 25(OH)D measurement, PTH measurement|
|Study Type :||Observational|
|Actual Enrollment :||74235 participants|
|Official Title:||LC-MS/MS Based 25(OH)D Status in a Large Central European Outpatient Cohort- Gender and Age Specific Differences|
|Actual Study Start Date :||January 2015|
|Actual Primary Completion Date :||December 2016|
|Actual Study Completion Date :||June 2017|
- Diagnostic Test: 25(OH)D measurement, PTH measurement
25(OH)D analyses by LC-MS/MS were performed as part of our routine clinical work with a commercial kit from Recipe (Munich, Germany) ; PTH was measured in lithium-heparin plasma using the PTH STAT assay from Roche Diagnostics (Mannheim, Germany) on a Cobas 8000 auto-analyzer.
- 25(OH)D measurement [ Time Frame: 2015-2016 ]Describe the 25(OH)D status in South-Tyrol,a region in central Europe, by a rigorously controlled, NIST 972a aligned LC-MS/MS method.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03388203
|Principal Investigator:||MARKUS HERRMANN, Medicine||Clinical Institute for Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Austria|