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Trial record 1 of 1 for:    NCT03057977
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EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Reduced Ejection Fraction (EMPEROR-Reduced)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT03057977
Recruitment Status : Active, not recruiting
First Posted : February 20, 2017
Last Update Posted : February 5, 2020
Eli Lilly and Company
Information provided by (Responsible Party):
Boehringer Ingelheim

Brief Summary:
The aim of the study is to investigate the safety and efficacy of empagliflozin versus placebo on top of guideline-directed medical therapy in patients with heart failure with reduced ejection fraction.

Condition or disease Intervention/treatment Phase
Heart Failure Drug: Empagliflozin Drug: Placebo Phase 3

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 3730 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Treatment
Official Title: A Phase III Randomised, Double-blind Trial to Evaluate Efficacy and Safety of Once Daily Empagliflozin 10 mg Compared to Placebo, in Patients With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)
Actual Study Start Date : March 6, 2017
Estimated Primary Completion Date : June 19, 2020
Estimated Study Completion Date : July 20, 2020

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Heart Failure

Arm Intervention/treatment
Experimental: Empagliflozin Drug: Empagliflozin
once daily

Placebo Comparator: Placebo Drug: Placebo
once daily

Primary Outcome Measures :
  1. Composite primary endpoint - Time to first event of adjudicated CV (Cardiovascular) death or adjudicated HHF (Hospitalisation for Heart Failure) in patients with Heart Failure with reduced Ejection Fraction (HFrEF) [ Time Frame: up to 38 months ]
    Composite primary endpoint - Time to first event of adjudicated CV (Cardiovascular) death or adjudicated HHF (Hospitalisation for Heart Failure) in patients with Heart Failure with reduced Ejection Fraction (HFrEF)

Secondary Outcome Measures :
  1. Occurrence of adjudicated HHF (Hospitalisation for Heart Failure) (first and recurrent) [ Time Frame: up to 38 months ]
    Occurrence of adjudicated HHF (Hospitalisation for Heart Failure) (first and recurrent)

  2. eGFR (Estimated Glomerular Filtration Rate) (CKD-EPI (Chronic Kidney Disease - Epidemiology Collaboration Equation))cr slope of change from baseline [ Time Frame: up to 38 months ]
    eGFR (Estimated Glomerular Filtration Rate) (CKD-EPI (Chronic Kidney Disease - Epidemiology Collaboration Equation))cr slope of change from baseline

  3. Time to first occurrence of chronic dialysis or renal transplant or sustained reduction of eGFR [ Time Frame: up to 38 months ]

    Time to first occurrence of chronic dialysis or renal transplant or sustained reduction of >= 40% eGFR (CKD-EPI)cr or

    • sustained eGFR (CKD-EPI)cr <15 mL/min/1.73 m2 for patients with baseline eGFR >=30 mL/min/1.73 m2
    • sustained eGFR (CKD-EPI)cr <10 mL/min/1.73 m2 for patients with baseline eGFR <30 mL/min/1.73 m2

  4. Time to first adjudicated HHF (Hospitalisation for Heart Failure) [ Time Frame: up to 38 months ]
    Time to first adjudicated HHF (Hospitalisation for Heart Failure)

  5. Time to adjudicated CV (Cardiovascular) death [ Time Frame: up to 38 months ]
    Time to adjudicated CV (Cardiovascular) death

  6. Time to all-cause mortality [ Time Frame: up to 38 months ]
    Time to all-cause mortality

  7. Time to onset of DM (Diabetes Mellitus) [ Time Frame: up to 38 months ]
    Time to onset of DM (Diabetes Mellitus)

  8. Change from baseline in clinical summary score (HF (Chronic Heart Failure) symptoms and physical limitations domains) of the Kansas City Cardiomyopathy Questionnaire (KCCQ) at week 52 [ Time Frame: Baseline and Week 52 ]
    Change from baseline in clinical summary score (HF (Chronic Heart Failure) symptoms and physical limitations domains) of the Kansas City Cardiomyopathy Questionnaire (KCCQ) at week 52

  9. Occurrence of all-cause hospitalisation (first and recurrent) [ Time Frame: up to 38 months ]
    Occurrence of all-cause hospitalisation (first and recurrent)

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion criteria:

  • Male or female patient age >= 18 years at screening. For Japan only: Age >= 20 years at screening
  • Patients with chronic HF (Chronic Heart Failure) NYHA (New York Heart Association Classification) class II-IV and reduced EF (Ejection Fraction) (LVEF (Left Ventricular Ejection Fraction) <=40%) and elevated NT-proBNP (N-terminal of the prohormone brain natriuretic peptide)

    • If EF >= 36% to <= 40%: NT-proBNP >= 2500 pg/ml or patients without AF (atrial fibrillation/atrial flutter) and NT-proBNP >= 5000 pg/ml for patients with AF
    • If EF >= 31% to <= 35%: NT-proBNP >= 1000 pg/ml for patients without AF and NT-proBNP >=2000 pg/ml for patients with AF
    • If EF<= 30%: NT-proBNP >= 600 pg/ml for patients without AF and NT-proBNP >=1200 pg/ml for patients with AF
    • EF ≤ 40% and hospitalization for heart failure in the past 12 months: NTproBNP ≥ 600 pg/ml for patients without AF and NT-proBNP >= 1200 pg/ml for patients with AF
  • Appropriate dose of medical therapy for HF consistent with prevailing local and international CV (Cardiovascular) guidelines, stable for at least 1 week prior to Visit 1
  • Appropriate use of medical devices such as cardioverter defibrillator (ICD) or a cardiac resynchronization therapy (CRT) consistent with prevailing local or international CV guidelines
  • Signed and dated written ICF (Informed Consent Form)
  • Further inclusion criteria apply

Exclusion criteria:

  • Myocardial infarction, coronary artery bypass graft surgery, or other major cardiovascular surgery, stroke or TIA (Transient Ischaemic Attack) in past 90 days prior to Visit 1
  • Heart transplant recipient, or listed for heart transplant
  • Acute decompensated HF
  • Systolic blood pressure (SBP) >= 180 mmHg at Visit 2.
  • Symptomatic hypotension and/or a SBP < 100 mmHg
  • Indication of liver disease
  • Impaired renal function, defined as eGFR (Estimated Glomerular Filtration Rate) < 20 mL/min/1.73 m2 (CKD-EPI (Chronic Kidney Disease - Epidemiology Collaboration Equation)) or requiring dialysis
  • History of ketoacidosis
  • Current use or prior use of a SGLT (Sodium-glucose co-transporter)-2 inhibitor or combined SGLT-1 and 2 inhibitor
  • Currently enrolled in another investigational device or drug study
  • Known allergy or hypersensitivity to empagliflozin or other SGLT-2 inhibitors
  • Women who are pregnant, nursing, or who plan to become pregnant while in the trial
  • Further exclusion criteria apply

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT03057977

Hide Hide 497 study locations
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United States, California
La Mesa Cardiac Center
La Mesa, California, United States, 91492
Long Beach Center for Clinical Research
Long Beach, California, United States, 90807
Merced Vein and Vascular Center
Merced, California, United States, 95340
University of California Irvine
Orange, California, United States, 92865
Covigilant Research, LLC
Riverside, California, United States, 92506
University of California
Torrance, California, United States, 90502
Blue Coast Cardiology
Vista, California, United States, 92083
United States, Colorado
Aurora Denver Cardiology Associates, PC
Aurora, Colorado, United States, 80012
South Denver Cardiology Associates, PC
Littleton, Colorado, United States, 80120
United States, Florida
Morton Plant Mease Health Care
Clearwater, Florida, United States, 33756
Nature Coast Clinical Research
Crystal River, Florida, United States, 34429
Avail Clinical Research, LLC
DeLand, Florida, United States, 32720
Integrative Research Associates
Fort Lauderdale, Florida, United States, 33312
Nature Coast Clinical Research
Inverness, Florida, United States, 34452
East Coast Institute for Research, LLC
Jacksonville, Florida, United States, 32216
Jacksonville Center for Clinical Research
Jacksonville, Florida, United States, 32216
Orlando Health Inc.
Orlando, Florida, United States, 32806
Cardiology Consultants, Inc
Pensacola, Florida, United States, 32501
Sarasota Memorial Hospital
Sarasota, Florida, United States, 34239
United States, Georgia
Grady Clinical Research Center
Atlanta, Georgia, United States, 30303
Augusta University
Augusta, Georgia, United States, 30912
Columbus Regional Research Institute
Columbus, Georgia, United States, 31904
Cardiovascular Group PC
Lawrenceville, Georgia, United States, 30046
Meridian Clinical Research, LLC
Savannah, Georgia, United States, 31406
United States, Illinois
Northwest Heart Clinical Research, LLC
Arlington Heights, Illinois, United States, 60005
University of Chicago
Chicago, Illinois, United States, 60637
Captain James A Lovell Federal Health Care Center
North Chicago, Illinois, United States, 60064
Rockford Cardiovascular Associates
Rockford, Illinois, United States, 61107
United States, Indiana
Midwest Cardiovascular Research and Education Foundation
Elkhart, Indiana, United States, 46514
St. Francis Medical Group-Indiana Heart Physicians, Inc
Indianapolis, Indiana, United States, 46237
Reid Hospital
Richmond, Indiana, United States, 47374
Beacon Medical Group Clinical Research
South Bend, Indiana, United States, 46601
United States, Kentucky
Krishnan Challappa M.D. PSC
Elizabethtown, Kentucky, United States, 42701
Research Integrity, LLC
Owensboro, Kentucky, United States, 42303
United States, Louisiana
Cambridge Medical Trials
Alexandria, Louisiana, United States, 71301
Louisiana Heart Center
Covington, Louisiana, United States, 70433
Clinical Trials of America LA, LLC
Monroe, Louisiana, United States, 71201
Tulane University Hospital and Clinic
New Orleans, Louisiana, United States, 70112
United States, Maryland
Anne Arundel Medical Center
Annapolis, Maryland, United States, 21401
Johns Hopkins University Hospital School of Medicine
Baltimore, Maryland, United States, 21218
MedStar Health Research Institute
Baltimore, Maryland, United States, 21237
Metropolitan Cardiovascular Consultants
Beltsville, Maryland, United States, 20705
Spectrum Clinical Research
Towson, Maryland, United States, 21204
United States, Massachusetts
Tufts Medical Center
Boston, Massachusetts, United States, 02111
East Mountain Medical Associates, PC
Great Barrington, Massachusetts, United States, 01230
United States, Michigan
Alpena General Hospital
Alpena, Michigan, United States, 49707
United States, Missouri
Saint Louis University
Saint Louis, Missouri, United States, 63110
Saint Louis, Missouri, United States, 63136
United States, Nevada
Palm Research Center
Las Vegas, Nevada, United States, 89128
United States, New York
Cardiac Care and Vascular Medicine, PLLC
Bronx, New York, United States, 10469
Trinity Medical WNY, PC
Cheektowaga, New York, United States, 14227
Northwell Health
Great Neck, New York, United States, 11021
Mount Sinai School of Medicine
Lake Success, New York, United States, 11041
St. Luke's Roosevelt Hospital
New York, New York, United States, 10025
Harlem Cardiology
New York, New York, United States, 10035
Stony Brook University Medical Center
Stony Brook, New York, United States, 11794
United States, North Carolina
Asheville Cardiology Associates
Asheville, North Carolina, United States, 28803
Kernodle Clinic West
Burlington, North Carolina, United States, 27215
The University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States, 27599-5021
Novant Health Heart and Vascular Institute
Charlotte, North Carolina, United States, 28204
Duke University Medical Center
Durham, North Carolina, United States, 27609
Clinical Research of Gastonia
Gastonia, North Carolina, United States, 28054
Clinical Trials of America, Inc
Lenoir, North Carolina, United States, 28645
United States, Ohio
Rama Research LLC
Marion, Ohio, United States, 43302
University of Toledo
Toledo, Ohio, United States, 43614
United States, Oklahoma
South Oklahoma Heart Research Group
Oklahoma City, Oklahoma, United States, 73135
United States, Pennsylvania
Doylestown Health Cardiology
Doylestown, Pennsylvania, United States, 18901
York Hospital, WellSpan Health
York, Pennsylvania, United States, 17403
United States, South Carolina
AnMed Health Clinical Research
Anderson, South Carolina, United States, 29621
Ralph H. Johnson VA Medical Center
Charleston, South Carolina, United States, 29401
Palmetto Health
Columbia, South Carolina, United States, 29203
William Jennings Bryan Dorn VA Medical Center
Columbia, South Carolina, United States, 29209
United States, Texas
Baylor Heart and Vascular Hospital
Dallas, Texas, United States, 75226
Soltero Cardiovascular Research Center
Dallas, Texas, United States, 75226
University of Texas Southwestern Medical Center
Dallas, Texas, United States, 75390-8837
Angiocardiac Care of Texas
Houston, Texas, United States, 77025
The Methodist Hospital
Houston, Texas, United States, 77030
Biopharma Informatic, Inc. Research Center
Houston, Texas, United States, 77084
The Heart Hospital
Plano, Texas, United States, 75093
United States, Utah
Alpine Research Organization
Farmington, Utah, United States, 84025
United States, Virginia
Cardiac Health Management Network, P.C.
Chester, Virginia, United States, 23836
Hunter Holmes McGuire VA Medical Center
Richmond, Virginia, United States, 23249
Salem VA Medical Center
Salem, Virginia, United States, 24153
United States, Wisconsin
Marshfield Clinic
Marshfield, Wisconsin, United States, 54449
Hospital Interzonal General de Agudos Dr Jose Penna
Bahia Blanca, Argentina, B8001DDU
Hospital Italiano Regional del Sur, Bahia Blanca
Bahia Blanca, Argentina, B8001HXM
Caba, Argentina, C1119ACN
Hospital Italiano de Buenos Aires
Caba, Argentina, C1199ABB
Centro Medico Dra Laura Maffei
Ciudad Autonoma Buenos Aires, Argentina, C1425AGC
Instituto Cardiovascular de Buenos Aires
Ciudad Autonoma Buenos Aires, Argentina, C1428ART
Glenny Corp. S.A. Bioclinica Argentina
Ciudad Autonoma Buenos Aires, Argentina, C1430CKE
Centro Médico Viamonte
Ciudad Autonoma de Bs As, Argentina, C1120AAC
Sanatorio Güemes
Ciudad Autónoma de Bs As, Argentina, C1180AAX
Instituto Medico Elsa Perez SRL (IMEP)
Ciudadela, Argentina, 1702
Clínica Colombo
Cordoba, Argentina, X5002AOQ
Instituto Médico DAMIC S.R.L.
Cordoba, Argentina, X5003DCE
Clinica Coronel Suarez SA
Coronel Suarez, Argentina, B7540DOL
Instituto de Cardiología de Corrientes
Corrientes, Argentina, W3400AMZ
Sanatorio Mayo Privado SA
Córdoba, Argentina, 5000
Centro de Investigaciones Clinicas Instituto del Corazon
Córdoba, Argentina, X5000EVQ
Sanatorio Allende S.A.
Córdoba, Argentina, X5000JHQ
Hospital Privado
Córdoba, Argentina, X5016KEH
Hospital Italiano de La Plata
La Plata, Argentina, B1900AXI
Centro de Investigaciones Médicas
Mar del Plata, Argentina, B7600FYK
Hospital Privado de Comunidad
Mar del Plata, Argentina, B7602CBM
Clínica Olivos
Olivos, Argentina, 1602
CER Instituto Médico
Quilmes, Argentina, B1878DVB
Instituto de Investigaciones Clínicas de Quilmes
Quilmes, Argentina, B1878GEG
Instituto de Investigaciones Clinicas de Rosario
Rosario, Argentina, 2000
Instituto Medico Fundación Grupo Colaborativo Rosario
Rosario, Argentina, 2000
Sanatorio Británico
Rosario, Argentina, 2000
Sanatorio Plaza
Rosario, Argentina, 2000
Sanatorio Parque
Rosario, Argentina, S2000DSV
Instituto CAICI
Rosario, Argentina, S2000PBJ
CORDIS S.A., Salta
Salta, Argentina, A4400ANW
Centro Cardiovascular Salta
Salta, Argentina, A4406BFP
Corporacion Medica de Gral. San Martin S.A.
San Martin, Argentina, B1650CSQ
Clinica Mayo
San Miguel de Tucuman, Argentina, 4000
Investigaciones Clinicas Tucuman
San Miguel de Tucumán, Argentina, T4000ICL
Centro Medico Luquez
San Vicente, Argentina, X5006CBI
Centro de Investigaciones Clínicas del Litoral
Santa Fe, Argentina, S3000FWO
Hospital "Dr. José Maria Cullen "
Santa Fé, Argentina, S3000EOZ
Instituto de Cardiología
Tucumán, Argentina, T4000JCU
CEMEDIC - Centro de Especialidades Medicas
Villa Luro, Argentina, C1440CFD
Australia, New South Wales
John Hunter Hospital
New Lambton Heights, New South Wales, Australia, 2305
Australia, Queensland
CORE Research Group
Milton, Queensland, Australia, 4064
Australia, South Australia
SA-Heart Ashford Specialist Centre
Ashford, South Australia, Australia, 5035
Heart and Vascular Research
Fullarton, South Australia, Australia, 5063
Australia, Victoria
The Northern Hospital
Epping, Victoria, Australia, 3076
St Vincent's Hospital Melbourne
Fitzroy, Victoria, Australia, 3065
University Hospital Geelong
Geelong, Victoria, Australia, 3220
Royal Melbourne Hospital
Parkville, Victoria, Australia, 3050
AZ Sint-Jan Brugge
Brugge, Belgium, 3000
C.H.U. de Charleroi
Charleroi, Belgium, 6000
AZ Sint-Blasius
Dendermonde, Belgium, 9200
Ziekenhuis Oost-Limburg - Campus Sint-Jan
Genk, Belgium, 3600
AZ Sint-Lucas - Campus Sint Lucas
Gent, Belgium, 9000
Grand Hôpital de Charleroi
Gilly, Belgium, 6060
Jessa Ziekenhuis - Campus Virga Jesse
Hasselt, Belgium, 3500
La Louvière - UNIV CHU Tivoli
La Louvière, Belgium, 7100
UZ Leuven
Leuven, Belgium, 3000
AZ Sint-Maarten
Mechelen, Belgium, 2800
Hospital Felicio Rocho
Belo Horizonte, Brazil, 30110-060
Hospital Vera Cruz
Belo Horizonte, Brazil, 30140-062
Cardresearch Cardiologia Assistencial e de Pesquisas Ltda
Belo Horizonte, Brazil, 30150-240
L2IP -Instituto de Pesquisas Clínicas Ltda.
Brasília, Brazil, 70200-730
ICDF - Instituto de Cardiologia do Distrito Federal
Brasília, Brazil, 70673-900
CECAP - Centro de Cardiologia Clínica
Brasília, Brazil, 70710-100
Hospital Angelina Caron
Campina Grande do Sul, Brazil, 83430-000
Centro Especializado em Cardiol Loema Instituto de Pesq Clin
Campinas, Brazil, 13010-001
IPCC - Instituto de Pesquisa Clínica de Campinas
Campinas, Brazil, 13060-080
CAEP - Centro Avançado de Estudos e Pesquisas Ltda.,Campinas
Campinas, Brazil, 13087-567
Hospital Universitário
Canoas, Brazil, 92425-900
IPCEM - Instituto de Pesquisa Clínica para Estudos Multicêntricos - Universidade de Caxias do Sul
Caxias do Sul, Brazil, 95070-560
PUC Trials - Núcleo de Pesquisa Clínica da Escola de Medicina da PUC-PR
Curitiba, Brazil, 80230-130
Hospital de Messejana Dr. Carlos Alberto Studart Gomes
Fortaleza, Brazil, 60846-190
Via Medica
Goiânia, Brazil, 74223-130
HC-UFG - Hospital das Clínicas da Universidade Federal de Goiás
Goiânia, Brazil, 74605-020
ICM - Instituto do Coracao de Marilia
Marília, Brazil, 17515-000
Hospital São Vicente de Paulo
Passo Fundo, Brazil, 99010-080
Santa Casa de Misericórdia de Porto Alegre
Porto Alegre, Brazil, 90035-074
Centro de Pesquisas em Diabetes
Porto Alegre, Brazil, 90035-170
Hospital de Clínicas de Porto Alegre
Porto Alegre, Brazil, 90035-903
Hospital Agamenon Magalhaes
Recife, Brazil, 52051-380
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto - USP
Ribeirão Preto, Brazil, 14048-900
Hospital Universitário Pedro Ernesto UERJ
Rio De Janeiro - RJ, Brazil, CEP 20551
CCBR - Rio de Janeiro - BR
Rio de Janeiro, Brazil, 22271-100
Santo André, Brazil, 09080-110
Praxis Pesquisa Médica
Santo André, Brazil, 09090-790
Fundacao Faculdade Regional de Medicina, Sao Jose
Sao Jose do Rio Preto, Brazil, 15090-000
Centro de Pesquisa Clinica - CPCLIN
Sao Paulo, Brazil, 01244-030
FGM - Clínica Paulista de Doenças Cardiovasculares
Sao Paulo, Brazil, 01323-000
CEPIC - Centro Paulista de Investigacao Clinica
Sao Paulo, Brazil, 04266-010
INCOR e Hospital das Clínicas da Universidade de São Paulo
Sao Paulo, Brazil, 05403-000
CEMEC - Centro Multidisciplinar de Estudos Clínicos
São Bernardo do Campo, Brazil, 09780-000
CDEC BRASIL - Centro de Desenvolvimento em Estudos Clínicos Brasil
São Paulo, Brazil, 04020-060
Dr. Consulta
São Paulo, Brazil, 04208-002
CEDOES - Diagnóstico e Pesquisa,Vitória
Vitória, Brazil, 29055-450
Santa Casa de Votuporanga
Votuporanga, Brazil, 15500-003
Canada, Alberta
Royal Alexandra Hospital
Edmonton, Alberta, Canada, T5H 3V9
Canada, British Columbia
Vancouver General Hospital
Vancouver, British Columbia, Canada, V5Z 1M9
St. Paul's Hospital
Vancouver, British Columbia, Canada, V6Z 1Y6
Victoria Heart Institute Foundation
Victoria, British Columbia, Canada, V8R 4R2
Canada, Manitoba
St. Boniface General Hospital
Winnipeg, Manitoba, Canada, R2H 2A6
Canada, New Brunswick
G.A. Research Associates Ltd
Moncton, New Brunswick, Canada, E1G 1A7
Canada, Nova Scotia
QEII Health Sciences Centre (Dalhousie University)
Halifax, Nova Scotia, Canada, B3H 2Y9
Canada, Ontario
Brampton Cardio Pulmonary Clinic
Brampton, Ontario, Canada, L6W 2X7
JBN Medical Diagnostic Services Inc.
Burlington, Ontario, Canada, L7M 4Y1
Cambridge Cardiac Care Inc.
Cambridge, Ontario, Canada, N1R 6V6
Curnew Medicine Professional Corporation
Hamilton, Ontario, Canada, L8L 0A9
Hamilton General Hospital
Hamilton, Ontario, Canada, L8L 2X2
PACE (Partners in Advanced Cardiac Evaluation)
Newmarket, Ontario, Canada, L3Y 2P6
M Heffernan Medicine Professional Corp.
Oakville, Ontario, Canada, L6K 3W7
Kawartha Cardiology Clinical Trials
Peterborough, Ontario, Canada, K9J 0B2
Heart Health Institute
Scarborough, Ontario, Canada, M1B 4Z8
Scarborough Cardiology Research
Scarborough, Ontario, Canada, M1E 5E9
Cardiovascular Contract Research Organization LTD
Sudbury, Ontario, Canada, P3E 5M4
Canadian Phase Onward Inc.
Toronto, Ontario, Canada, M3J 2C5
North York Diagnostic and Cardiac Centre
Toronto, Ontario, Canada, M6B 1N6
Diabetes Heart Research Centre
Toronto, Ontario, Canada, M6G 1M2
Mohan Babapulle Medicine Professional Medicine
Waterloo, Ontario, Canada, N2T 0C1
Dr. Bruce Lubelsky
Willowdale, Ontario, Canada, M2K 2W2
Dr. Louis C.H. Yao
York, Ontario, Canada, M9N 1W4
Canada, Quebec
ViaCar Recherche Clinique Inc
Greenfield Park, Quebec, Canada, J4V 2G8
Centre de Dépistage et Recherche Cardiovasculaire Rive-Sud
Longeuil, Quebec, Canada, J4M 2X1
Clinique Santé Cardio MC
Montreal, Quebec, Canada, H1T 3Y7
Montreal General Hospital - McGill University Health Centre
Montreal, Quebec, Canada, H3G 1A4
McGill University Health Centre (MUHC)
Montreal, Quebec, Canada, H4A 3J1
Centre de sante et de services sociaux de Beauce
Saint George-de-Beauce, Quebec, Canada, G5Y 4T8
Canada, Saskatchewan
Royal University Hospital
Saskatoon, Saskatchewan, Canada, S7N 0W8
IUCPQ (Laval University)
Quebec, Canada, G1V 4G5
Cardiovascular Institute and Fu Wai Hospital
Beijing, China, 100037
Beijing Friendship Hospital
Beijing, China, 100050
First Hospital of Jilin University
Changchun, China, 130021
Hunan Provincial People's Hospital
Changsha, China, 410005
2nd Xiangya Hospital of Central South University
Changsha, China, 410011
The Third Hospital of Changsha
Changsha, China, 410015
Dongguan People's Hospital
Dongguan, China, 523059
The First Affiliated Hospital of Fujian Medical University
Fuzhou, China, 350005
The First Afiliated Hospital, Sun Yet-sen University
Guangzhou, China, 510080
Guangzhou First Municipal People's Hospital
Guangzhou, China, 510180
Haikou People's Hospital
Haikou, China, 570208
HaiNan Provincial People's Hospital
Haikou, China, 570311
The First Affiliated Hospital of Lanzhou University
Lanzhou, China, 730000
The Second Affiliated Hospital of Lanzhou Medical University
Lanzhou, China, 730030
The Affiliated Hospital of Southwest Medical University
Luzhou, China, 646099
Nanchang University Affiliated 3rd Hospital
Nanchang, China, 330008
First Hospital Affiliated with Nanjing Medical University
Nanjing, China, 210029
Huashan Hospital, Fudan University
Shanghai, China, 200040
General Hospital of Shenyang Military Region
Shenyang, China, 110015
Shengjing Hospital of China Medical University
Shenyang, China, 110072
Tianjin Union Medical Center Nankai University Affiliated Hospital
Tianjin, China, 300121
Tongji Hospital, Tongji University
Wuhan, China, 430030
Renmin Hospital of Wuhan University
Wuhan, China, 430060
First Affiliated Hospital of Xi'an JiaoTong University
Xi'an, China, 710061
Yanbian University Hospital
Yanji, China, 133000
the first people hospital of Yue Yang
Yueyang, China, 414000
Affiliated Hospital of Jiangsu University
Zhenjiang, China, 212013
Poliklinika Humanitas
Bilovec, Czechia, 74301
Medicus Services Ltd.
Brandys Nad, Czechia, 250 01
Internal and Cardiology Practice, MUDr. Karel Kamenik, Brno
Brno, Czechia, 603 00
Vojenska nemocnice Brno
Brno, Czechia, 63600
Edumed s.r.o
Broumov, Czechia, 55001
MUDr. Jan Hubac, s.r.o. Kardiologicka ambulance
Chrudim, Czechia, 53702
Nemocnice ve Frydku-Mistku, prispevkova organizace
Frydek-Mistek, Czechia, 73818
KardioLouny s.r.o.
Louny, Czechia, 440 01
Zdenek Vomacka
Olomouc, Czechia, 779 00
PV-Kardiologie s.r.o.
Pardubice, Czechia, 53002
University Hospital Motol
Prag 5, Czechia, 15006
General Faculty Hospital, Prague
Prague 2, Czechia, 128 08
Thomayer Hospital
Praha 4 - Krc, Czechia, 140 59
Kardio Vaclavik s.r.o.
Prerov, Czechia, 75000
Kardiologicka ambulance s.r.o.
Pribram VIII, Czechia, 26101
Masaryk Hospital, Usti nad Labem
Usti nad Labem, Czechia, 40113
Angiocor s.r.o
Zlin, Czechia, 76001
KIGE s.r.o
Znojmo, Czechia, 66902
HOP de Bayonne
Bayonne, France, 64100
HOP Jean Minjoz
Besançon, France, 25030
HOP Louis Pradel
Bron, France, 69500
HOP Côte de Nacre
Caen, France, 14033
HOP Henri Mondor
Créteil, France, 94010
HOP Arnaud de Villeneuve
Montpellier, France, 34295
HOP La Pitié Salpêtrière
Paris, France, 75651
Centre Hospitalier de Pau
Pau, France, 64046
HOP Haut-Lévêque
Pessac, France, 33600
HOP Rangueil
Toulouse, France, 31059
INS Louis Mathieu
Vandoeuvre-lès-Nancy, France, 54511
Universitätsklinikum Aachen, AöR
Aachen, Germany, 52074
Praxis Dr. Rieker, Berlin
Berlin, Germany, 10789
Charité - Universitätsmedizin Berlin
Berlin, Germany, 13353
Klinikum Bielefeld gGmbH
Bielefeld, Germany, 33604
Praxis Dr. Menzel
Dessau-Roßlau, Germany, 06846
St. Johannes Hospital Dortmund
Dortmund, Germany, 44137
Städtisches Klinikum Dresden
Dresden, Germany, 01067
Helios Klinikum Erfurt
Erfurt, Germany, 99089
Studienzentrum Bocholderstraße
Essen, Germany, 45355
ClinPhenomics GmbH & Co KG, Frankfurt
Frankfurt, Germany, 60594
Universitätsmedizin Göttingen, Georg-August-Universität
Göttingen, Germany, 37075
Asklepios Klinik St. Georg
Hamburg, Germany, 20099
Medizinische Hochschule Hannover
Hannover, Germany, 30625
Universitätsklinikum Heidelberg
Heidelberg, Germany, 69120
Universitätsklinikum des Saarlandes
Homburg, Germany, 66421
Universitätsklinikum Jena
Jena, Germany, 07740
Universitätsklinikum Schleswig-Holstein, Campus Kiel
Kiel, Germany, 24105
Asklepios Klinik Langen-Seligenstadt GmbH
Langen, Germany, 63225
Märkische Gesundheitsholding GmbH & Co. KG, Klinikum Lüdenscheid
Lüdenscheid, Germany, 58515
Praxis Dr. Sarnighausen, Lüneburg
Lüneburg, Germany, 21339
Deutsches Herzzentrum München
München, Germany, 80636
Kardiologische Gemeinschaftspraxis Nienburg
Nienburg, Germany
Kardiologische Praxis Papenburg
Papenburg, Germany, 26871
Universitätsklinikum Regensburg
Regensburg, Germany, 93053
Praxis Dr. Stenzel, Riesa
Riesa, Germany, 01587
Zentrum für Klinische Forschung
Wangen, Germany, 88239
Josephs-Hospital Warendorf
Warendorf, Germany, 48231
Wuppertal, Germany, 42283
Lausmed Kft. Outpatient Unit of Internal Medicine
Baja, Hungary, 6500
Belgyogyaszati es Kardiologiai Maganrendelo
Bekescsaba, Hungary, 5600
Clinexpert Kft.
Budapest, Hungary, 1033
Gottsegen Gyorgy Hungarian Instit.of Cardiology,Budapest
Budapest, Hungary, 1096
Bajcsy-Zsilinszky Hospital and Clinic
Budapest, Hungary, 1106
Semmelweis University
Budapest, Hungary, 1122
Magyar Honvedseg Egeszsegugyi Kozpont
Budapest, Hungary, 1134
Uzsoki Street Hospital, Budapest
Budapest, Hungary, 1145
Nehezlegzes Ambulancia
Debrecen, Hungary, 4027
Bugat Pal Hospital, Gyongyos
Gyongyos, Hungary, 3200
Dorottya Kanizsai Hospital
Nagykanizsa, Hungary, 8800
Dr. Nagy Laszlo Kardiologiai Maganrendeles
Oroshaza, Hungary, 5900
Da Vinci Maganklinika
Pecs, Hungary, 7635
Pecsi Tudomanyegyetem
Pécs, Hungary, 7623
Fejer County Saint George University Teaching Hospital
Szekesfehervar, Hungary, 8000
Veszpremi Sziv es Egeszseg Centrum
Veszprem, Hungary, 8200
Doctor Jivraj Mehta Smarak Health Foundation
Ahmedabad, India, 380007
Kamalnayan Bajaj Hospital
Aurangabad, India, 431 005
Narayana Institute of Cardiac Sciences
Bangalore, India, 560099
Rajarajeswari Medical College
Bengaluru, India, 560074
Madras Medical Mission,
Chennai, India, 600 037
Apollo Speciality Hospital
Chennai, India, 600035
Medanta-The Medicity
Gurgaon, India, 122001
Siddhi Hospital
Nashik, India, 422007
Vijan Cardiac and Critical Care Centre
Nasik, India, 422005
Batra Hospital and Medical Research Centre
New Delhi, India, 110 062
GB Pant Hospital
New Delhi, India, 110002
Fortis Escorts Heart Institute
New Delhi, India, 110025
Sir Gangaram Hospital
New Delhi, India, 110060
Azienda Ospedaliera G. Rummo
Benevento, Italy, 82100
ASST Papa Giovanni XXIII - A.O. Papa Giovanni XXIII
Bergamo, Italy, 24127
Azienda Ospedaliera Universitaria Arcispedale Sant'Anna
Cona (FE), Italy, 44124
Ospedale della Val di Chiana Santa Margherita
Cortona (AR), Italy, 52040
Centro Cardiologico Monzino-IRCCS
Milano, Italy, 20138
Azienda Ospedaliera Universitaria "Federico II"
Napoli, Italy, 80131
Azienda Ospedaliera Universitaria Pisana
Pisa, Italy, 56126
Umberto I Pol. di Roma-Università di Roma La Sapienza
Roma, Italy, 00161
Azienda Ospedaliera Sant'Andrea-Università di Roma La Sapienza
Roma, Italy, 00189
Azienda Servizi Sanitari 1 Triestina
Trieste, Italy, 34128
Kasugai Municipal Hospital
Aichi, Kasugai, Japan, 486-8510
Nagoya Kyoritsu Hospital
Aichi, Nagoya, Japan, 454-0933
Japanese Red Cross Nagoya Daini Hospital
Aichi, Nagoya, Japan, 466-8650
Toyota Memorial Hospital
Aichi, Toyota, Japan, 471-8513
Chiba Heart Clinic
Chiba, Chiba, Japan, 263-0043
Kimitsu Chuo Hospital
Chiba, Kisarazu, Japan, 292-8535
Seikeikai New Tokyo Heart Clinic
Chiba, Matsudo, Japan, 271-0077
Ehime Prefectural Central Hospital
Ehime, Matsuyama, Japan, 790-0024
Matsuyama Shimin Hospital
Ehime, Matsuyama, Japan, 790-0067
Uwajima City Hospital
Ehime, Uwajima, Japan, 798-8510
Fukuiken Saiseikai Hospital
Fukui, Fukui, Japan, 918-8503
Fukuoka University Chikushi Hospital
Fukuoka, Chikushino, Japan, 818-8502
Fukuokaken Saiseikai Futsukaichi Hospital
Fukuoka, Chikushino, Japan, 818-8516
Saiseikai Fukuoka General Hospital
Fukuoka, Fukuoka, Japan, 810-0001
National Hospital Organization Kyushu Medical Center
Fukuoka, Fukuoka, Japan, 810-8563
Kyushu University Hospital
Fukuoka, Fukuoka, Japan, 812-8582
Aso Co.,Ltd Iizuka Hospital
Fukuoka, Iizuka, Japan, 820-8505
Steel Memorial Yawata Hospital
Fukuoka, Kitakyushu, Japan, 805-8508
Japan Community Health Care Organization Kyushu Hospital
Fukuoka, Kitakyushu, Japan, 806-8501
Ogaki Municipal Hospital
Gifu, Ogaki, Japan, 503-8502
Chuno Kosei Hospital
Gifu, Seki, Japan, 501-3802
Fukuyama City Hospital
Hiroshima, Fukuyama, Japan, 721-8511
JA Hiroshima General Hospital
Hiroshima, Hatsukaichi, Japan, 738-8503
Shobara Red Cross Hospital
Hiroshima, Shobara, Japan, 727-0013
National Hospital Organization Hakodate Hospital
Hokkaido, Hakodate, Japan, 041-8512
Teine Keijinkai Clinic
Hokkaido, Sapporo, Japan, 006-0811
Tomakomai City Hospital
Hokkaido, Tomakomai, Japan, 053-8567
Hyogo Prefectural Amagasaki General Medical Center
Hyogo, Amagasaki, Japan, 660-8550
Hyogo Brain and Heart Center
Hyogo, Himeji, Japan, 670-0981
National Hospital Organization Kobe Medical Center
Hyogo, Kobe, Japan, 654-0155
Mito Medical Center
Ibaraki, Higashiibaraki-gun, Japan, 311-3193
National Hospital Organization Kanazawa Medical Center
Ishikawa, Kanazawa, Japan, 920-8650
Mitoyo General Hospital
Kagawa, Kanonji, Japan, 769-1695
Kagawa Prefectural Central Hospital
Kagawa, Takamatsu, Japan, 760-8557
Kanagawa Cardiovascular and Respiratory Center
Kanagawa, Yokohama, Japan, 236-0051
Japanese Red Cross Kumamoto Hospital
Kumamoto, Kumamoto, Japan, 861-8520
Seiwakai Suizenji Touya Hospital
Kumamoto, Kumamoto, Japan, 862-0950
Kumamoto Rosai Hospital
Kumamoto, Yatsushiro, Japan, 866-8533
Uji-Tokushukai Medical Center
Kyoto, Uji, Japan, 611-0041
Sendai Kousei Hospital
Miyagi, Sendai, Japan, 980-0873
The Cardiovascular Center of Sendai
Miyagi, Sendai, Japan, 981-3133
National Hospital Organization Sendai Medical Center
Miyagi, Sendai, Japan, 983-8520
Miyazaki Medical Association Hospital
Miyazaki, Miyazaki, Japan, 880-0834
Hokushin General Hospital
Nagano, Nakano, Japan, 383-8505
Nagasaki Medical Center
Nagasaki, Omura, Japan, 856-8562
Okayama City General Medical Center
Okayama, Okayama, Japan, 700-8557
Naha City Hospital
Okinawa, Naha, Japan, 902-8511
Nanbu Tokushukai Hospital
Okinawa, Shimajiri-gun, Japan, 901-0493
Urasoe General Hospital
Okinawa, Urasoe, Japan, 901-2132
Kitano Hospital
Osaka, Osaka, Japan, 530-8480
Yodogawa Christian Hospital
Osaka, Osaka, Japan, 533-0024
Seichokai Bell Land General Hospital
Osaka, Sakai, Japan, 599-8247
Hokusetsu General Hospital
Osaka, Takatsuki, Japan, 569-8585
San-Ai Hospital
Saitama, Saitama, Japan, 338-0837
Kosekai Iwatsuki-minami Hospital
Saitama, Saitama, Japan, 339-0033
Kusatsu General Hospital
Shiga, Kusatsu, Japan, 525-8585
Tokushima Prefectural Central Hospital
Tokushima, Tokushima, Japan, 770-8539
National Hospital Organization Tokyo Medical Center
Tokyo, Meguro-ku, Japan, 152-8902
Ome Municipal General Hospital
Tokyo, Ome, Japan, 198-0042
Tokyo Rosai Hospital
Tokyo, Ota-ku, Japan, 143-0013
Sekino Hospital
Tokyo, Toshima-ku, Japan, 171-0014
Minami Wakayama Medical Center
Wakayama, Tanabe, Japan, 646-8558
Kanmon Medical Center
Yamaguchi, Shimonoseki, Japan, 752-8510
Korea, Republic of
Dong-A University Hospital
Busan, Korea, Republic of, 602-715
Inje University Busan Paik Hospital
Busan, Korea, Republic of, 614-735
Chungbuk National University Hospital
Cheongju, Korea, Republic of, 361-771
Chungnam National University Hospital
Daejeon, Korea, Republic of, 301-721
Gachon University Gil Medical Center
Incheon, Korea, Republic of, 21565
Seoul National University Hospital
Seoul, Korea, Republic of, 03080
Severance Hospital
Seoul, Korea, Republic of, 03722
Asan Medical Center
Seoul, Korea, Republic of, 05505
Samsung Medical Center
Seoul, Korea, Republic of, 06351
Korea University Guro Hospital
Seoul, Korea, Republic of, 08308
Seoul National University Bundang Hospital
Sungnam, Korea, Republic of, 463-707
Wonju Severance Christian Hosp
Wonju, Korea, Republic of, 220-701
Hospital Cardiologica Aguascalientes
Aguascalientes, Mexico, 20230
Instituto Nacional de Cardiologia Ignacio Chavez
Ciudad de Mexico, Mexico, 14080
Centro de Investigacion Biomedica y Farmaceutica, S.C.
Distrito Federal, Mexico, 03100
Unidad de Investigacion Clinica Cardiometabolica de Occident
Guadalajara, Mexico, 44150
Diseño y Planeación en Investigación Médica SC
Guadalajara, Mexico, 44656
Cardiologia Clinica e Intervencionista
Guadalajara, Mexico, 44670
Centro de Investigación Clinica Acelerada, S.C.
Mexico, Mexico, 07020
Instituto Cardiovascular de Monclova, S de RL de CV
Monclova, Mexico, 25750
CEDOPEC-Ctro Esp en Diab, Obesidad y Prev de Enf Cardiovasc
México, Mexico, 11650
Hospital Universitario Dr Jose Eleuterio Gonzalez
Nuevo Leon, Mexico, 64460
Centro Integral Medico SJR S.C.
San Juan del Rio, Mexico, 76800
Cardioarritmias e Investigación S.C
San Luis Potosi, Mexico, 78213
Centro de Investigacion Cardiovascular y Metabolica
Tijuana, Mexico, 22500
Centro de Investigacion Alberto Bazzoni S.A. de C.V.
Torreon, Mexico, 27000
Hospital Dr Angel Leano
Zapopan, Mexico, 45200
Ziekenhuisgroep Twente locatie Almelo
Almelo, Netherlands, 7609 PP
BovenIJ Ziekenhuis
Amsterdam, Netherlands, 1034 CS
Onze Lieve Vrouwe Gasthuis, Locatie West
Amsterdam, Netherlands, 1061 AE
Amsterdam UMC Locatie VUMC
Amsterdam, Netherlands, 1081HV
Onze Lieve Vrouwe Gasthuis
Amsterdam, Netherlands, 1091AC
Amsterdam UMC, Locatie AMC
Amsterdam, Netherlands, 1105 AZ
Rode Kruis Ziekenhuis Beverwijk
Beverwijk, Netherlands, 1942 LE
Tergooiziekenhuizen locatie Blaricum
Blaricum, Netherlands, 1261 AN
Amphia Ziekenhuis
Breda, Netherlands, 4818 CK
HMC Bronovo
Den Haag, Netherlands, 2597 AX
Ziekenhuis Gelderse Vallei
EDE, Netherlands, 6716 RP
Catharina Ziekenhuis
Eindhoven, Netherlands, 5623 EJ
Universitair Medisch Centrum Groningen
Groningen, Netherlands, 9713 GZ
Zuyderland Medisch Centrum
Heerlen, Netherlands, 6419 PC
Vasculair Onderzoek Centrum
Hoorn, Netherlands, 1624 NP
Maastricht Universitair Medisch Centrum
Maastricht, Netherlands, 6229 HX
Diaconessenhuis Meppel
Meppel, Netherlands, 7943 KA
St. Antonius ziekenhuis, locatie Nieuwegein
Nieuwegein, Netherlands, 3435 CM
Radboud Universitair Medisch Centrum
Nijmegen, Netherlands, 6525 GL
Ziekenhuis Bernhoven Uden
Uden, Netherlands, 5406 PT
Vie Curi Medisch Centrum
Venlo, Netherlands, 5912 BL
De Heel - Zaans Medisch Centrum
Zaandam, Netherlands, 1502 DV
Gelre Ziekenhuis Zutphen
Zutphen, Netherlands, 7207 AE
KLIMED Marek Klimkiewicz
Bialystok, Poland, 15-765
Univ. Clinic Hosp, Bialystok
Bialystok, Poland, 15276
American Heart of Poland Sp. z o.o.
Bielsko-Biala, Poland, 43-316
Polsko-Amerykanskie Kliniki Serca
Chorzow, Poland, 32-500
American Heart of Poland Sp. z o.o.
Dabrowa Gornicza, Poland, 41-300
Poradnia Kardiologiczna Jaroslaw Jurowiecki
Gdansk, Poland, 80-286
University Clinical Center, Gdansk
Gdansk, Poland, 80952
Indywidualna Specjalistyczna Praktyka Lekarska
Gdynia, Poland, 81-157
NZOZ Pro-Cordis Sopockie Centrum Bad. Kardiolog.
Gdynia, Poland, 81-423
Specialistic Cardiology&Hypertension Out-patient Clin,Kielce
Kielce, Poland, 25525
Leszek Bryniarski Specialized Medical Cabinet
Krakow, Poland, 30-082
Krakow Specialistic Hospital of John Paul II
Krakow, Poland, 31-202
SANTA FAMILIA Centrum Badan, Profilaktyki i Leczenia
Lodz, Poland, 90-302
Nzoz Salus
Lodz, Poland, 91-302
Individual Specialized Practice
Lodz, Poland, 94-255
Lowickie Cardiology Center
Lowicz, Poland, 99-400
American Heart of Poland Sp. z o.o.
Nysa, Poland, 48-300
Medicome Sp. z o.o.
Oswiecim, Poland, 32-600
Specialized Practice Dr. Janusz Spyra
Ruda Slaska, Poland, 41-709
Centrum Medyczne Medyk
Rzeszow, Poland, 35-055
Lukmed Lukasz Wozniak
Siedlce, Poland, 08-110
Clinmedica Research Omc sp. z o.o. sp.k., Skierniewice
Skierniewice, Poland, 96-100
KO-MED Centra Kliniczne Staszow
Staszow, Poland, 28-200
The Provincial Polyclinical Hospital in Torun
Torun, Poland, 87-100
American Heart of Poland Sp. z o.o.
Tychy, Poland, 43-100
American Heart of Poland Sp. z o.o.
Ustron, Poland, 43-450
Central Hospital of Medical Academy, Warsaw
Warsaw, Poland, 02-097
McM Polimedica
Warszawa, Poland, 02-777
4. Military Clinical Hospital with Polyclinic SP ZOZ
Wroclaw, Poland, 50-981
Zgierskie Center of Cardiology MED-PRO
Zgierz, Poland, 95-100
Specialist Hospital J. Dietla NZOZ Specialized Clinic "Gemini"
Zychlin, Poland, 62-571
Hospital Quiron. I.C.U.
Barcelona, Spain, 08023
Hospital Santa Creu i Sant Pau
Barcelona, Spain, 08026
Hospital Universitario Virgen de la Arrixaca
El Palmar, Spain, 30120
Hospital de Bellvitge
L'Hospitalet de Llobregat, Spain, 08907
Hospital Clínico San Carlos
Madrid, Spain, 28040
Hospital Universitario 12 de Octubre
Madrid, Spain, 28041
Hospital La Paz
Madrid, Spain, 28046
Hospital Virgen de la Victoria
Malaga, Spain, 29010
Complejo Hospitalario Universitario de Orense
Orense, Spain, 32005
Hospital Clínico de Santiago
Santiago de Compostela, Spain, 15706
Hospital Clínico Universitario de Valladolid
Valladolid, Spain, 47003
United Kingdom
Barnet General Hospital
Barnet, United Kingdom, EN5 3DJ
Park & St Francis Surgery
Eastleigh, United Kingdom, SO53 4ST
Wycombe General Hospital
High Wycombe, United Kingdom, HP11 2TT
Glenfield Hospital
Leicester, United Kingdom, LE3 9QP
St Bartholomew's Hospital
London, United Kingdom, EC1A 7BE
Luton and Dunstable University Hospital
Luton, United Kingdom, LU4 0DZ
St Mary's Hospital
Newport, United Kingdom, PO30 5TG
Morriston Hospital
Swansea, United Kingdom, SA6 6NL
Sponsors and Collaborators
Boehringer Ingelheim
Eli Lilly and Company
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Study Chair: Boehringer Ingelheim Boehringer Ingelheim

Layout table for additonal information
Responsible Party: Boehringer Ingelheim Identifier: NCT03057977    
Other Study ID Numbers: 1245.121
2016-002280-34 ( EudraCT Number )
First Posted: February 20, 2017    Key Record Dates
Last Update Posted: February 5, 2020
Last Verified: February 2020

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Studies a U.S. FDA-regulated Drug Product: Yes
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Heart Failure
Heart Diseases
Cardiovascular Diseases
Sodium-Glucose Transporter 2 Inhibitors
Molecular Mechanisms of Pharmacological Action
Hypoglycemic Agents
Physiological Effects of Drugs