Neuroimaging and Neuromonitoring in Critically Ill Children With Sepsis
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|ClinicalTrials.gov Identifier: NCT03055455|
Recruitment Status : Recruiting
First Posted : February 16, 2017
Last Update Posted : July 30, 2020
|Condition or disease||Intervention/treatment|
|Septic Shock||Diagnostic Test: MR imaging|
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Official Title:||Neuroimaging and Neuromonitoring in Critically Ill Children With Sepsis|
|Actual Study Start Date :||February 1, 2017|
|Estimated Primary Completion Date :||December 31, 2020|
|Estimated Study Completion Date :||December 31, 2020|
Children with severe sepsis or septic shock
Diagnostic Test: MR imaging
Conventional structural imaging will be combined with advanced neuroimaging modalities to evaluate integrity of white matter tracts, regional brain perfusion, and the 3-dimensional volume of specific brain structures.
- MRI [ Time Frame: 2-10 days ]Detection of signal abnormality on the patient's brain MRI scan.
- CAR [ Time Frame: Daily for 10 days ]Trends in functionality of CAR over the first 10 days of severe sepsis. Identification of the optimal blood pressure range where CAR is most functional.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03055455
|Contact: Madeline Winters, BSN, RNfirstname.lastname@example.org|
|United States, Pennsylvania|
|The Children's Hospital of Philadelphia||Recruiting|
|Philadelphia, Pennsylvania, United States, 19104|
|Contact: Madeline Winters, BSN, RN 267-426-5788 email@example.com|
|Principal Investigator:||Matthew Kirschen, MD, PhD||CHOP|