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Trial record 13 of 278 for:    Panama

Prevalence, Strain Circulation and Disease Burden Study of Seasonal Influenza A and B in Panama, Selected Countries of Central America and the Caribbean From the Year 2010 to 2015

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ClinicalTrials.gov Identifier: NCT02885246
Recruitment Status : Completed
First Posted : August 31, 2016
Last Update Posted : September 27, 2018
Sponsor:
Information provided by (Responsible Party):
GlaxoSmithKline

Brief Summary:
The purpose of this study is to assess the prevalence, strain circulation and disease burden of seasonal Influenza A and B in Panama, selected countries of Central America and the Caribbean from the Year 2010 to 2015.

Condition or disease Intervention/treatment
Influenza, Human Other: Data collection

Detailed Description:

The Gorgas Memorial Institute for Health Studies (ICGES) is a public health institution established in Panama dedicated to health research and disease prevention. It has been performing virological isolations of influenza and is a part of the World Health Organisation (WHO) Global Influenza Surveillance and Response System (GISRS) and a direct collaborator of the CDC.

From 2010 a sentinel surveillance program is being conducted in Panama within the ICGES to collect data on influenza and other respiratory viruses using CDC guidance for Respiratory Disease Surveillance. This study aims to utilize this data source for analyzing the burden of influenza within the region.


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Study Type : Observational
Actual Enrollment : 1 participants
Observational Model: Other
Time Perspective: Retrospective
Official Title: Prevalence, Strain Circulation and Disease Burden of Seasonal Influenza A and B in Panama, Selected Countries of Central America and the Caribbean From the Year 2010 to 2015
Actual Study Start Date : September 11, 2017
Actual Primary Completion Date : September 17, 2018
Actual Study Completion Date : September 17, 2018

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Flu Flu Shot

Group/Cohort Intervention/treatment
Influenza Group
All subjects who have laboratory confirmed diagnosis of influenza (laboratory confirmed case) and reported in the national influenza surveillance system from the Year 2010-2015.
Other: Data collection
The ICGES database of Panama will be checked for all seasonal influenza A and/or B positive cases reported via influenza surveillance programs from 2010 to 2015.




Primary Outcome Measures :
  1. Occurrence of seasonal influenza A and/or B cases by age, virus subtype and strain lineage, in Panama, selected countries of Central America and the Caribbean (using the data reported via National Influenza Surveillance Program). [ Time Frame: From January 2010 to December 2015 ]
    Assessment by age ranges- <1, 1-4, 5-9, 10-14, 15-19, 20-24, 25-44, 45-49, 50-59, 60-64 and ≥65 years, virus subtype- A-virus subtype (AH1N1/A H3N2) and B-strain lineage (Victoria and Yamagata).


Secondary Outcome Measures :
  1. Occurrence of clinical features and outcomes (clinical symptoms, duration of illness, complications) experienced by subjects who have laboratory confirmed diagnosis seasonal influenza A and/or B. [ Time Frame: From January 2010 to December 2015 ]
    Clinical features and outcomes experienced by influenza positive subjects by type of influenza (seasonal influenza A and/or B) in different seasons from 2010-2015.

  2. Evaluation of frequency of seasonal influenza A and/or B cases reported in different temporal and geographical locations. [ Time Frame: From January 2010 to December 2015 ]
    Assessment by geographical distribution by country and by region within the country (if data available).

  3. Occurrence of influenza caused by B-strain and presented by B lineages among the study population by age and by region. [ Time Frame: From January 2010 to December 2015 ]
    Assessment by age ranges- <1, 1-4, 5-9, 10-14, 15-19, 20-24, 25-44, 45-49, 50-59, 60-64 and ≥65 and by selected study regions.

  4. Comparison of characteristics of the influenza B-infection as observed in the database and the B-strain included in the trivalent influenza vaccine. [ Time Frame: From January 2010 to December 2015 ]
    Estimation of the proportion of matched B-strains and mis-matched B-strains.



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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
The Total population will include all subjects included in the study. Information will only be collected for all eligible subjects (aggregated) captured by the ICGES Database.
Criteria

Inclusion Criteria:

  • All subjects diagnosed with seasonal influenza A and/or B, reported in the ICGES database of Panama, from January 2010 to December 2015.

Exclusion Criteria:

  • N/A.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02885246


Locations
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Panama
GSK Investigational Site
Panama, Panama
Sponsors and Collaborators
GlaxoSmithKline
Investigators
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Study Director: GSK Clinical Trials GlaxoSmithKline

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Responsible Party: GlaxoSmithKline
ClinicalTrials.gov Identifier: NCT02885246     History of Changes
Other Study ID Numbers: 205049
First Posted: August 31, 2016    Key Record Dates
Last Update Posted: September 27, 2018
Last Verified: September 2018

Keywords provided by GlaxoSmithKline:
Panama
Influenza B
Influenza A
Strain circulation
Database

Additional relevant MeSH terms:
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Influenza, Human
Orthomyxoviridae Infections
RNA Virus Infections
Virus Diseases
Respiratory Tract Infections
Respiratory Tract Diseases