Working…
ClinicalTrials.gov
ClinicalTrials.gov Menu

Gingival Wetness and Gingival Crevicular Fluid Volume in Patients With Dry Mouth

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT00750828
Recruitment Status : Completed
First Posted : September 11, 2008
Last Update Posted : September 11, 2008
Sponsor:
Information provided by:
Hacettepe University

Study Description
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information
Brief Summary:
The investigators questioned whether patients with dry mouth complaints display any reduction in residual saliva coating the gingiva and other selected mucosal surfaces. We further intended to test the hypothesis that Gingival Crevicular Fluid volume in patients with dry mouth could be different from that of control subjects. Correlations between gingival/mucosal wetness; and unstimulated whole salivary flow rate or minor salivary gland secretion rates and the correlations between clinical periodontal status and salivary measures were also attempted.

Condition or disease
Xerostomia Sjogren's Syndrome

Study Design
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Layout table for study information
Study Type : Observational
Actual Enrollment : 28 participants
Observational Model: Case-Control
Time Perspective: Cross-Sectional
Official Title: Gingival Wetness and Gingival Crevicular Fluid Volume in Patients With Dry Mouth
Study Start Date : January 2004
Actual Primary Completion Date : December 2007
Actual Study Completion Date : March 2008

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Dry Mouth

Groups and Cohorts
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information


Outcome Measures
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Eligibility Criteria
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   46 Years to 56 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

The data for this study were taken from 28 subjects at the Department of Periodontology, Hacettepe University from 2004 to 2007. The study group consisted of 14 patients with dry mouth complaints. All of them had the diagnosis of Sjögren's syndrome and ten of them were on therapy for sicca symptoms.

Fourteen randomly selected age-matched systemically healthy females were also included as a control group

Criteria

Inclusion Criteria:

  • For test group dry mouth complaints and with a diagnosis ofSjogren's Syndrome

Exclusion Criteria:

  • Other medical problems that effect salivary glands
Contacts and Locations
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00750828


Locations
Layout table for location information
Turkey
Department of Periodontology, Faculty of Dentistry, Hacettepe University,
Ankara, Turkey, 06100
Sponsors and Collaborators
Hacettepe University
Investigators
Layout table for investigator information
Study Director: Burak Demiralp, DDS PhD Hacettepe University Faculty of Dentistry Department of Periodontology
More Information
Go to 
Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information
Layout table for additonal information
Responsible Party: Burak Demiralp, Hacettepe University Faculty of Dentistry Department of Periodontology
ClinicalTrials.gov Identifier: NCT00750828    
Other Study ID Numbers: Hacettepe # FON 03/6-14
First Posted: September 11, 2008    Key Record Dates
Last Update Posted: September 11, 2008
Last Verified: September 2008
Keywords provided by Hacettepe University:
Saliva
Sjögren's Syndrome
GCF
Oral Mucosal Wetness
Additional relevant MeSH terms:
Layout table for MeSH terms
Sjogren's Syndrome
Xerostomia
Arthritis, Rheumatoid
Arthritis
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases
Salivary Gland Diseases
 Mouth Diseases
Stomatognathic Diseases
Dry Eye Syndromes
Lacrimal Apparatus Diseases
Eye Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases