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Brain Changes in Pediatric OSA

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT05368077
Recruitment Status : Recruiting
First Posted : May 10, 2022
Last Update Posted : June 30, 2022
Sponsor:
Information provided by (Responsible Party):
Rajesh Kumar, PhD, University of California, Los Angeles

No Study Results Posted on ClinicalTrials.gov for this Study
Recruitment Status : Recruiting
Estimated Primary Completion Date : April 30, 2023
Estimated Study Completion Date : July 31, 2023
Publications:
Ehlert, L., Roy, B., Sahib, A., Song, X., Singh, S., Townsley, M., Kang, D.W., Aysola, R., Wen, E., Woo, M.A., Harper, R.M. & Kumar, R. Diffusion tensor imaging shows brain tissue changes before and after positive airway pressure treatment in patients with obstructive sleep apnea. Society for Neuroscience Annual Meeting, Washington, DC, USA, 2017.
Sahib, A., Roy, B., Song, X., Singh, S., Aysola, R., Kang, D.W., Woo, M.A. & Kumar, R. Brain axonal and myelin changes after positive airway pressure treatment in patients with obstructive sleep apnea. Joint Annual Meeting International Society for Magnetic Resonance in Medicine, Paris, France, 2018.
Keith, T.Z., Low, J.A., Reynolds, M.R., Patel, P.G. & Ridley, K.P. Higher-order factor structure of the differential ability scales-II: consistency across ages 4 to 17. Psychology in the Schools 47: 676-697, 2010.
Achenbach, T.M. The child behavior checklist and related instruments. In: The use of psychological testing for treatment planning and outcomes assessment, 2nd ed, edited by. Mahwah, NJ, US: Lawrence Erlbaum Associates Publishers, 1999, p. 429-466.
Ellis, E.M., Zarndt, R., Ho, B., Hopkins, S. & Powell, F.L. Effects of non-steroid anti-inflammatory drugs on the human hypoxic ventilatory response and acclimatization. The FASEB Journal 26: 1150.1152- 1150.1152, 2012.
Ehlert, L., Roy, B., Sahib, A.K., Song, X., Singh, S., Townsley, M., Kang, D.W., Aysola, R., Wen, E., Woo, M.A., Harper, R.M. & Kumar, R. Diffusion tensor imaging shows brain tissue changes before and after positive airway pressure treatment in patients with obstructive sleep apnea. Society for Neuroscience Annual Meeting, Washington, D.C., 2017.
Paruthi, S. Evaluation of suspected obstructive sleep apnea in children. Edited by A.G. Hoppin, 2019.
Rubinstein, B.J. & Baldassari, C.M. An Update on the management of pediatric obstructive sleep apnea. Curr Treat Options Pediatr 1: 211-223, 2015.
Elliott, C.D. Differential Ability Scales : introductory and technical handbook. San Antonio: Psychological Corp: Harcourt Brace Jovanovich, 1990.
Achenbach TM, R.L. Manual for the ASEBA school-based forms and profiles. Burlington: University of Vermont, Research Center for Children , Youth and Families, 2001.
Barmpoutis, A. & Jiachen, Z. Diffusion kurtosis imaging: robust estimation from DW-MRI using homogeneous polynomials. 2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Chicago, IL: 262-265, 2011.