Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

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ClinicalTrials.gov Identifier: NCT04211480

Recruitment Status : Active, not recruiting

First Posted : December 26, 2019

Last Update Posted : October 12, 2022

View this study on Beta.ClinicalTrials.gov

Sponsor:

Collaborators:

Xiangya Hospital of Central South University

PLA 923 Hospital

Information provided by (Responsible Party):

Bioray Laboratories

No Study Results Posted on ClinicalTrials.gov for this Study

About Study Results Reporting on ClinicalTrials.gov

Recruitment Status :	Active, not recruiting
Estimated Primary Completion Date :	October 15, 2023
Estimated Study Completion Date :	December 1, 2023

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Fu B, Liao J, Chen S, Li W, Wang Q, Hu J, Yang F, Hsiao S, Jiang Y, Wang L, Chen F, Zhang Y, Wang X, Li D, Liu M, Wu Y. CRISPR-Cas9-mediated gene editing of the BCL11A enhancer for pediatric beta0/beta0 transfusion-dependent beta-thalassemia. Nat Med. 2022 Aug;28(8):1573-1580. doi: 10.1038/s41591-022-01906-z. Epub 2022 Aug 4.

Brusson M, Miccio A. Genome editing approaches to beta-hemoglobinopathies. Prog Mol Biol Transl Sci. 2021;182:153-183. doi: 10.1016/bs.pmbts.2021.01.025. Epub 2021 Mar 1.

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