Sickle Cell Trait and Exercise, Effect of Hot Environment (TDex)

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ClinicalTrials.gov Identifier: NCT04028791

Recruitment Status : Completed

First Posted : July 23, 2019

Last Update Posted : July 23, 2019

View this study on Beta.ClinicalTrials.gov

Sponsor:

Collaborator:

Institut National de la Santé Et de la Recherche Médicale, France

Information provided by (Responsible Party):

Sophie Antoine-Jonville, University of the French West Indies and French Guiana

No Study Results Posted on ClinicalTrials.gov for this Study

About Study Results Reporting on ClinicalTrials.gov

Recruitment Status :	Completed
Actual Primary Completion Date :	July 1, 2019
Actual Study Completion Date :	July 1, 2019

Publications:

Bergeron MF, Cannon JG, Hall EL, Kutlar A. Erythrocyte sickling during exercise and thermal stress. Clin J Sport Med. 2004 Nov;14(6):354-6. doi: 10.1097/00042752-200411000-00005.

Connes P, Sara F, Hardy-Dessources MD, Marlin L, Etienne F, Larifla L, Saint-Martin C, Hue O. Effects of short supramaximal exercise on hemorheology in sickle cell trait carriers. Eur J Appl Physiol. 2006 May;97(2):143-50. doi: 10.1007/s00421-006-0155-3. Epub 2006 Feb 28.

Faure C, Charlot K, Henri S, Hardy-Dessources MD, Hue O, Antoine-Jonville S. Impaired glucose tolerance after brief heat exposure: a randomized crossover study in healthy young men. Clin Sci (Lond). 2016 Jun 1;130(12):1017-25. doi: 10.1042/CS20150461. Epub 2016 Mar 15.

Kark JA, Posey DM, Schumacher HR, Ruehle CJ. Sickle-cell trait as a risk factor for sudden death in physical training. N Engl J Med. 1987 Sep 24;317(13):781-7. doi: 10.1056/NEJM198709243171301.

Kerle KK, Nishimura KD. Exertional collapse and sudden death associated with sickle cell trait. Mil Med. 1996 Dec;161(12):766-7.

Kerle KK, Runkle GP. Sickle cell trait and sudden death in athletes. JAMA. 1996 Nov 13;276(18):1472. No abstract available.

Le Gallais D, Bile A, Mercier J, Paschel M, Tonellot JL, Dauverchain J. Exercise-induced death in sickle cell trait: role of aging, training, and deconditioning. Med Sci Sports Exerc. 1996 May;28(5):541-4. doi: 10.1097/00005768-199605000-00001.

Monchanin G, Connes P, Wouassi D, Francina A, Djoda B, Banga PE, Owona FX, Thiriet P, Massarelli R, Martin C. Hemorheology, sickle cell trait, and alpha-thalassemia in athletes: effects of exercise. Med Sci Sports Exerc. 2005 Jul;37(7):1086-92. doi: 10.1249/01.mss.0000170128.78432.96.

O'Connor FG, Bergeron MF, Cantrell J, Connes P, Harmon KG, Ivy E, Kark J, Klossner D, Lisman P, Meyers BK, O'Brien K, Ohene-Frempong K, Thompson AA, Whitehead J, Deuster PA. ACSM and CHAMP summit on sickle cell trait: mitigating risks for warfighters and athletes. Med Sci Sports Exerc. 2012 Nov;44(11):2045-56. doi: 10.1249/MSS.0b013e31826851c2.

Quattrone RD, Eichner ER, Beutler A, Adams WB, O'Connor FG. Exercise collapse associated with sickle cell trait (ECAST): case report and literature review. Curr Sports Med Rep. 2015 Mar-Apr;14(2):110-6. doi: 10.1249/JSR.0000000000000137.

Wirthwein DP, Spotswood SD, Barnard JJ, Prahlow JA. Death due to microvascular occlusion in sickle-cell trait following physical exertion. J Forensic Sci. 2001 Mar;46(2):399-401.

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