Pirfenidone Plus M-DDO Gel in Moderate and Severe Acne
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|ClinicalTrials.gov Identifier: NCT03076320|
Recruitment Status : Recruiting
First Posted : March 10, 2017
Last Update Posted : June 7, 2018
University of Guadalajara
Hospital Civil de Guadalajara
Information provided by (Responsible Party):
Juan Armendáriz-Borunda, University of Guadalajara
No Study Results Posted on ClinicalTrials.gov for this Study
|Recruitment Status :||Recruiting|
|Estimated Primary Completion Date :||January 31, 2019|
|Estimated Study Completion Date :||March 31, 2019|
Gollnick HP, Finlay AY, Shear N; Global Alliance to Improve Outcomes in Acne. Can we define acne as a chronic disease? If so, how and when? Am J Clin Dermatol. 2008;9(5):279-84. Review.
Kang S, Cho S, Chung JH, Hammerberg C, Fisher GJ, Voorhees JJ. Inflammation and extracellular matrix degradation mediated by activated transcription factors nuclear factor-kappaB and activator protein-1 in inflammatory acne lesions in vivo. Am J Pathol. 2005 Jun;166(6):1691-9.
Macías-Barragán J, Sandoval-Rodríguez A, Navarro-Partida J, Armendáriz-Borunda J. The multifaceted role of pirfenidone and its novel targets. Fibrogenesis Tissue Repair. 2010 Sep 1;3:16. doi: 10.1186/1755-1536-3-16.
Zhou R, Jiang X. Effects of adapalene-benzoyl peroxide combination gel in treatment or maintenance therapy of moderate or severe acne vulgaris: a meta-analysis. Ann Dermatol. 2014 Feb;26(1):43-52. doi: 10.5021/ad.2014.26.1.43. Epub 2014 Feb 17.
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