Occipital Nerve Stimulation in Medically Intractable Chronic Cluster Headache (ICON)

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ClinicalTrials.gov Identifier: NCT01151631

Recruitment Status : Completed

First Posted : June 28, 2010

Last Update Posted : February 28, 2020

View this study on Beta.ClinicalTrials.gov

Sponsor:

Collaborators:

Maastricht University Medical Center

Erasmus Medical Center

Technical University of Twente

Canisius-Wilhelmina Hospital

University of Copenhagen

University Hospital, Ghent

Royal Free Hospital NHS Foundation Trust

Medtronic

Centre Hospitalier Régional de la Citadelle

Schmerzklinik Kiel

University Hospital Schleswig-Holstein

National Institute of Neuroscience, Budapest

Information provided by (Responsible Party):

MDFerrari, Leiden University Medical Center

No Study Results Posted on ClinicalTrials.gov for this Study

About Study Results Reporting on ClinicalTrials.gov

Recruitment Status :	Completed
Actual Primary Completion Date :	September 2018
Actual Study Completion Date :	March 2019

Publications:

Burns B, Watkins L, Goadsby PJ. Treatment of intractable chronic cluster headache by occipital nerve stimulation in 14 patients. Neurology. 2009 Jan 27;72(4):341-5. doi: 10.1212/01.wnl.0000341279.17344.c9.

Burns B, Watkins L, Goadsby PJ. Treatment of medically intractable cluster headache by occipital nerve stimulation: long-term follow-up of eight patients. Lancet. 2007 Mar 31;369(9567):1099-106. doi: 10.1016/S0140-6736(07)60328-6.

Magis D, Allena M, Bolla M, De Pasqua V, Remacle JM, Schoenen J. Occipital nerve stimulation for drug-resistant chronic cluster headache: a prospective pilot study. Lancet Neurol. 2007 Apr;6(4):314-21. doi: 10.1016/S1474-4422(07)70058-3.

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Wilbrink LA, de Coo IF, Doesborg PGG, Mulleners WM, Teernstra OPM, Bartels EC, Burger K, Wille F, van Dongen RTM, Kurt E, Spincemaille GH, Haan J, van Zwet EW, Huygen FJPM, Ferrari MD; ICON study group. Safety and efficacy of occipital nerve stimulation for attack prevention in medically intractable chronic cluster headache (ICON): a randomised, double-blind, multicentre, phase 3, electrical dose-controlled trial. Lancet Neurol. 2021 Jul;20(7):515-525. doi: 10.1016/S1474-4422(21)00101-0.

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