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Trial record 17 of 43 for:    FLUORIDE ION AND TRICLOSAN

Clinical Study to Examine Brushing on Dental Implants

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT00762619
Recruitment Status : Completed
First Posted : September 30, 2008
Results First Posted : January 25, 2011
Last Update Posted : January 25, 2011
Sponsor:
Information provided by:
Colgate Palmolive

Study Type Interventional
Study Design Allocation: Randomized;   Intervention Model: Parallel Assignment;   Masking: Single (Participant);   Primary Purpose: Treatment
Condition Gingival Diseases
Interventions Drug: Fluoride
Drug: Triclosan, fluoride
Enrollment 105
Recruitment Details subjects were recruited by the PI at the clinical site
Pre-assignment Details subjects were screened for medical and oral health criteria and given the assigned study treatment to brush with for the next 6 months. Enrolled subjects all had 1 dental implant and 1 natural tooth identified and used for clinical data information.
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment. fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
Period Title: Overall Study
Started 55 50
Completed 55 50
Not Completed 0 0
Arm/Group Title A - Fluoride Control B - Postive Control Total
Hide Arm/Group Description Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment. fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment. Total of all reporting groups
Overall Number of Baseline Participants 55 50 105
Hide Baseline Analysis Population Description
[Not Specified]
Age, Categorical  
Measure Type: Count of Participants
Unit of measure:  Participants
Number Analyzed 55 participants 50 participants 105 participants
<=18 years
0
   0.0%
0
   0.0%
0
   0.0%
Between 18 and 65 years
53
  96.4%
48
  96.0%
101
  96.2%
>=65 years
2
   3.6%
2
   4.0%
4
   3.8%
Age Continuous  
Mean (Standard Deviation)
Unit of measure:  Years
Number Analyzed 55 participants 50 participants 105 participants
54.71  (9.6) 55.22  (11.6) 54.95  (10.56)
Sex: Female, Male  
Measure Type: Count of Participants
Unit of measure:  Participants
Number Analyzed 55 participants 50 participants 105 participants
Female
29
  52.7%
24
  48.0%
53
  50.5%
Male
26
  47.3%
26
  52.0%
52
  49.5%
Region of Enrollment  
Measure Type: Number
Unit of measure:  Participants
Israel Number Analyzed 55 participants 50 participants 105 participants
55 50 105
1.Primary Outcome
Title Mombelli Plaque Index (mPI) for Natural Teeth
Hide Description

Modified Plaque Index (mPI)is a Dental plaque scale as follows 0 = No plaque,

1 = Separate flecks of plaque at the cervical margin;2 = Plaque can be seen by naked eye.3 = Abundance of soft matter. The lower the number the less plaque is present on the tooth.

Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description:
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
Overall Number of Participants Analyzed 55 50
Mean (Standard Deviation)
Unit of Measure: units on a scale
1.96  (0.63) 1.82  (0.62)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Control, B - Postive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
2.Primary Outcome
Title Mombelli Plaque Index (mPI) for Natural Teeth
Hide Description

Modified Plaque Index (mPI) is a Dental plaque scale as follows 0 = No plaque,

1 = Separate flecks of plaque at the cervical margin;2 = Plaque can be seen by naked eye.3 = Abundance of soft matter. The lower the number the less plaque is present on the tooth.

Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description:
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
Overall Number of Participants Analyzed 55 50
Mean (Standard Deviation)
Unit of Measure: units on a scale
2.05  (0.59) 1.73  (0.68)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Control, B - Postive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
3.Primary Outcome
Title Mombelli Plaque Index (mPI) for Dental Implants
Hide Description

Modified Plaque Index (mPI) is a dental plaque scale as follows 0 = No plaque,

1 = Separate flecks of plaque at the cervical margin;2 = Plaque can be seen by naked eye.3 = Abundance of soft matter. The lower the number the less plaque is present on the tooth.

Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description:
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
Overall Number of Participants Analyzed 55 50
Mean (Standard Deviation)
Unit of Measure: units on a scale
1.62  (0.63) 1.35  (0.48)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Control, B - Postive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
4.Primary Outcome
Title Mombelli Plaque Index (mPI) for Dental Implants
Hide Description

Modified Plaque Index (mPI) is a dental plaque scale as follows 0 = No plaque,

1 = Separate flecks of plaque at the cervical margin;2 = Plaque can be seen by naked eye.3 = Abundance of soft matter. The lower the number the less plaque is present on the tooth.

Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description:
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
Overall Number of Participants Analyzed 55 50
Mean (Standard Deviation)
Unit of Measure: units on a scale
1.71  (0.56) 1.45  (0.53)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Control, B - Postive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
5.Primary Outcome
Title Löe-Silness Gingival Index Score (GI) - Natural Teeth
Hide Description Gingivitis score(GI) is defined: 0 = Absence of inflammation,1 = Mild inflammation–slight change in color and little change in texture,2 = Moderate inflammation–moderate glazing,redness,edema & hypertrophy,3 = Severe inflammation–marked redness and hypertrophy tendency for spontaneous bleeding. Each tooth is scored on 6 surfaces:mesio-facial;2)mid-facial;3)disto-facial;4)mesio-lingual;5)mid-lingualand 6)disto-lingual. A whole mouth score = adding all the GI scores & dividing by the total of number of sites scored. 3rd molars and teeth with restorations or crowns will be excluded.
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description:
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
Overall Number of Participants Analyzed 55 50
Mean (Standard Deviation)
Unit of Measure: units on a scale
1.3  (0.73) 1.17  (0.61)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Control, B - Postive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
6.Primary Outcome
Title Löe-Silness Gingival Index Score (GI) - Natural Teeth
Hide Description Gingivitis score(GI) is defined: 0 = Absence of inflammation,1 = Mild inflammation-slight change in color and little change in texture,2 = Moderate inflammation-moderate glazing,redness,edema & hypertrophy,3 = Severe inflammation-marked redness and hypertrophy tendency for spontaneous bleeding.Each tooth is scored on 6 surfaces:mesio-facial;2)mid-facial;3)disto-facial;4)mesio-lingual;5)mid-lingualand 6)disto-lingual. A whole mouth score = adding all the GI scores & dividing by the total of number of sites scored. 3rd molars and teeth with restorations or crowns will be excluded.
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description:
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
Overall Number of Participants Analyzed 55 50
Mean (Standard Deviation)
Unit of Measure: units on a scale
1.29  (0.79) 1.01  (0.8)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Control, B - Postive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
7.Primary Outcome
Title Löe-Silness Gingival Index Score (GI)- Dental Implants
Hide Description Gingivitis Score (GI) is defined: 0 = Absence of inflammation,1=Mild inflammation-slight change in color and little change in texture,2 = Moderate inflammation-moderate glazing,redness,edema & hypertrophy,3 = Severe inflammation-marked redness and hypertrophy tendency for spontaneous bleeding. Each tooth is scored on 6 surfaces:mesio-facial;2)mid-facial;3)disto-facial;4)mesio-lingual;5)mid-lingualand 6)disto-lingual. A whole mouth score=adding all the GI scores & dividing by the total of number of sites scored. 3rd molars and teeth with restorations or crowns will be excluded.
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description:
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
Overall Number of Participants Analyzed 55 50
Mean (Standard Deviation)
Unit of Measure: units on a scale
1.27  (0.67) 1.12  (0.63)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Control, B - Postive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
8.Primary Outcome
Title Löe-Silness Gingival Index Score (GI)- Dental Implants
Hide Description Gingivitis Score (GI) is defined: 0 = Absence of inflammation,1 = Mild inflammation-slight change in color and little change in texture,2 = Moderate inflammation-moderate glazing,redness,edema & hypertrophy,3 = Severe inflammation-marked redness and hypertrophy tendency for spontaneous bleeding. Each tooth is scored on 6 surfaces:mesio-facial;2)mid-facial;3)disto-facial;4)mesio-lingual;5)mid-lingualand 6)disto-lingual. A whole mouth score=adding all the GI scores & dividing by the total of number of sites scored. 3rd molars and teeth with restorations or crowns will be excluded.
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description:
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
Overall Number of Participants Analyzed 55 50
Mean (Standard Deviation)
Unit of Measure: units on a scale
1.24  (0.81) 0.99  (0.73)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Control, B - Postive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
9.Primary Outcome
Title Gingival Bleeding on Probing (BOP) Using Sulcus Bleeding Index for Teeth
Hide Description Sulcus bleeding index for teeth is explained here. Gums around teeth are scored:0 = gingiva of normal texture & color, no bleeding;1 = gingiva normal, bleeds on probing;2 = bleeding on probing,change in color, no oedema; 3 = bleeding on probing,change in color, slight oedema;4 = bleeding on probing, change in color, obvious oedema;5=bleeding on probing, spontaneous bleeding, change in color, marked oedema.
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description:
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
Overall Number of Participants Analyzed 55 50
Mean (Standard Deviation)
Unit of Measure: Units on a scale
0.77  (0.8) 0.51  (0.67)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Control, B - Postive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
10.Primary Outcome
Title Gingival Bleeding on Probing (BOP) Using Sulcus Bleeding Index for Teeth
Hide Description Sulcus bleeding index for teeth is explained here. Gums around teeth are scored:0 = gingiva of normal texture & color, no bleeding;1 = gingiva normal, bleeds on probing;2 = bleeding on probing,change in color, no oedema;3 = bleeding on probing,change in color, slight oedema;4 = bleeding on probing,change in color, obvious oedema;5 = bleeding on probing, spontaneous bleeding,change in color,marked oedema.
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description:
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
Overall Number of Participants Analyzed 55 50
Mean (Standard Deviation)
Unit of Measure: Units on a scale
0.877  (0.88) 0.53  (0.76)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Control, B - Postive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
11.Primary Outcome
Title Gingival Bleeding on Probing (BOP) Using the Modified Sulcus Bleeding Index for Implants
Hide Description Gingival bleeding on probing (BOP) using the modified sulcus bleeding index for implants. Scale equals 0 = No bleeding when periodontal probe is passed along the gingival margin;1 = Isolated bleeding spots visible;2 = Blood forms a confluent red line on the gingival margin;3 = Heavy or profuse bleeding.
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description:
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
Overall Number of Participants Analyzed 55 50
Mean (Standard Deviation)
Unit of Measure: Units on a scale
0.65  (0.78) 0.48  (0.68)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Control, B - Postive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
12.Primary Outcome
Title Gingival Bleeding on Probing (BOP) Using the Modified Sulcus Bleeding Index for Implants
Hide Description Gingival bleeding on probing (BOP) using the modified sulcus bleeding index for implants. Scale equals 0 = No bleeding when periodontal probe is passed along the gingival margin;1 = Isolated bleeding spots visible;2 = Blood forms a confluent red line on the gingival margin;3 = Heavy or profuse bleeding.
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description:
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
Overall Number of Participants Analyzed 55 50
Mean (Standard Deviation)
Unit of Measure: Units on a scale
0.81  (0.9) 0.45  (0.69)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Control, B - Postive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
13.Primary Outcome
Title A.Actinomycetemcomitans (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are Least means square (LSM)determined by baseline adjusted means including Standard Error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (Colony Forming Units)
6.269  (0.006) 5.002  (0.1117)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
14.Primary Outcome
Title A.Actinomycetemcomitans (DNA Probe Analysis)- Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data point is Least means square (LSM) determined by baseline adjusted means including Standard Error of Means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
6.201  (0.1117) 4.669  (0.1325)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
15.Primary Outcome
Title A.Actinomycetemcomitans (DNA Probe Analysis)- Dental Implant
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implant. Data point is Least means square (LSM) determined by baseline adjusted means including Standard Error of Means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.814  (0.1262) 4.446  (0.1589)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
16.Primary Outcome
Title A.Actinomycetemcomitans (DNA Probe Analysis)- Dental Implant
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implant. Data point is Least means square (LSM) determined by baseline adjusted means including Standard Error of Means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.664  (0.1222) 4.339  (0.1908)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
17.Primary Outcome
Title C.Rectus (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.69  (0.1269) 3.322  (0.1548)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
18.Primary Outcome
Title C.Rectus (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.578  (0.1403) 2.798  (0.172)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
19.Primary Outcome
Title C.Rectus (DNA Probe Analysis) - Dental Implant
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.46  (0.1226) 3.015  (0.1843)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
20.Primary Outcome
Title C.Rectus (DNA Probe Analysis) - Dental Implant
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.318  (0.1318) 2.758  (0.2106)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
21.Primary Outcome
Title Capnocytophaga sp. (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.676  (0.05921) 4.526  (0.06476)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANOVA
Comments [Not Specified]
22.Primary Outcome
Title Capnocytophaga sp. (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.644  (0.07209) 4.411  (0.07971)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
23.Primary Outcome
Title Capnocytophaga sp. (DNA Probe Analysis) - Dental Implant
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.391  (0.07532) 4.243  (0.08163)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
24.Primary Outcome
Title Capnocytophaga sp. (DNA Probe Analysis) - Dental Implant
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.356  (0.07716) 4.268  (0.08752)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
25.Primary Outcome
Title E.Corrodens (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM)determined by baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
6.47  (0.1477) 5.822  (0.1583)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
26.Primary Outcome
Title E.Corrodens (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM)determined by baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
6.417  (0.1808) 5.682  (0.1937)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
27.Primary Outcome
Title E.Corrodens (DNA Probe Analysis) - Dental Implant
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM)determined by baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
6.21  (0.148) 5.639  (0.162)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
28.Primary Outcome
Title E.Corrodens (DNA Probe Analysis) - Dental Implant
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM)determined by baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
6.242  (0.1619) 5.482  (0.1791)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
29.Primary Outcome
Title E.Saburreum (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.229  (0.1199) 4.385  (0.1328)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
30.Primary Outcome
Title E.Saburreum (DNA Probe Analysis)- Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM)detemined by using baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.079  (0.1424) 3.571  (0.1655)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
31.Primary Outcome
Title E.Saburreum (DNA Probe Analysis) - Dental Implant
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.012  (0.1065) 3.861  (0.1222)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
32.Primary Outcome
Title E.Saburreum (DNA Probe Analysis) - Dental Implant
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.733  (0.1287) 3.372  (0.1728)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
33.Primary Outcome
Title F.Nucleatum (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM)determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.337  (0.1773) 4.403  (0.123)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
34.Primary Outcome
Title F.Nucleatum (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error of means (SEM)
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.243  (0.1265) 3.405  (0.1327)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
35.Primary Outcome
Title F.Nucleatum (DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM)determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.89  (0.1277) 3.637  (0.1354)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
36.Primary Outcome
Title F.Nucleatum (DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM)determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.602  (0.1348) 2.425  (0.1474)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
37.Primary Outcome
Title Neissera sp. (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.638  (0.1203) 4.508  (0.1336)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
38.Primary Outcome
Title Neissera sp. (DNA Probe Analysis) Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.702  (0.1301) 4.658  (0.1604)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
39.Primary Outcome
Title Neissera sp. (DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.405  (0.1151) 3.955  (0.1193)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
40.Primary Outcome
Title Neissera sp. (DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.585  (0.1546) 4.415  (0.2199)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
41.Primary Outcome
Title P.Gingivalis (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error of means (SEM)
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
6.166  (0.1438) 5.183  (0.1705)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
42.Primary Outcome
Title P.Gingivalis (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM)
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
6.071  (0.1675) 4.951  (0.2125)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
43.Primary Outcome
Title P.Gingivalis (DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error of means (SEM)
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.784  (0.1533) 4.926  (0.1789)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
44.Primary Outcome
Title P.Gingivalis (DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error of means (SEM)
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.562  (0.1995) 4.642  (0.2578)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
45.Primary Outcome
Title P.Intermedia (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.091  (0.1526) 3.853  (0.1824)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
46.Primary Outcome
Title P.Intermedia (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.007  (0.1499) 3.803  (0.1875)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
47.Primary Outcome
Title P.Intermedia (DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.544  (0.1555) 3.853  (0.2115)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
48.Primary Outcome
Title P.Intermedia (DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.329  (0.1617) 3.803  (0.3178)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
49.Primary Outcome
Title P.Melaninogenica (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.066  (0.1067) 3.935  (0.1171)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
50.Primary Outcome
Title P.Melaninogenica (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for both natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.062  (0.1141) 3.691  (0.1252)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
51.Primary Outcome
Title P.Melaninogenica (DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.406  (0.0982) 3.363  (0.11309)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
52.Primary Outcome
Title P.Melaninogenica (DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.387  (0.1131) 3.155  (0.1303)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
53.Primary Outcome
Title Solobacterium (S.Moorei)(DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
6.511  (0.1553) 5.237  (0.1608)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
54.Primary Outcome
Title Solobacterium (S.Moorei)(DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
6.081  (0.2425) 4.487  (0.2476)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
55.Primary Outcome
Title Solobacterium (S.Moorei)(DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.767  (0.0346) 4.701  (0.02777)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
56.Primary Outcome
Title Solobacterium (S.Moorei)(DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.046  (0.3545) 3.899  (0.4863)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
57.Primary Outcome
Title Streptococci (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means )SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.995  (0.1175) 4.495  (0.1234)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
58.Primary Outcome
Title Streptococci (DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.867  (0.1195) 4.109  (0.1255)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
59.Primary Outcome
Title Streptococci (DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means )SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5  (0.1317) 3.263  (0.1383)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
60.Primary Outcome
Title Streptococci (DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means )SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
4.665  (0.1431) 2.404  (0.1503)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
61.Primary Outcome
Title T.Forsythia (DNA Probe Analysis)- Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for both natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
6.408  (0.1348) 5.143  (0.1474)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
62.Primary Outcome
Title T.Forsythia (DNA Probe Analysis)-Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
6.286  (0.1628) 4.926  (0.182)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
63.Primary Outcome
Title T.Forsythia (DNA Probe Analysis)- Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for both Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
6.19  (0.1637) 4.628  (0.1831)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
64.Primary Outcome
Title T.Forsythia (DNA Probe Analysis)- Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for both Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
6.08  (0.1691) 4.633  (0.2153)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
65.Primary Outcome
Title Veillonella sp.(DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error (SEM)
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.82  (0.1185) 4.927  (0.1245)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
66.Primary Outcome
Title Veillonella sp.(DNA Probe Analysis) - Natural Teeth
Hide Description 14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error (SEM).
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.746  (0.1282) 4.563  (0.1346)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
67.Primary Outcome
Title Veillonella sp.(DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error (SEM)
Time Frame 3 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.472  (0.1408) 4.485  (0.1494)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
68.Primary Outcome
Title Veillonella sp.(DNA Probe Analysis) - Dental Implants
Hide Description 14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error (SEM)
Time Frame 6 months
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title A - Fluoride Only Control B - Positive Control
Hide Arm/Group Description:
Fluoride only (Ultrabrite)
fluoride/triclosan/copolymer toothpaste
Overall Number of Participants Analyzed 55 50
Least Squares Mean (Standard Error)
Unit of Measure: Log cfu (colony forming units)
5.364  (0.1425) 4.186  (0.1511)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection A - Fluoride Only Control, B - Positive Control
Comments The null hypothesis states that there is no difference between groups.
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.05
Comments [Not Specified]
Method ANCOVA
Comments [Not Specified]
Time Frame 6 months
Adverse Event Reporting Description [Not Specified]
 
Arm/Group Title A - Fluoride Control B - Postive Control
Hide Arm/Group Description Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment. fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
All-Cause Mortality
A - Fluoride Control B - Postive Control
Affected / at Risk (%) Affected / at Risk (%)
Total   --/--   --/-- 
Show Serious Adverse Events Hide Serious Adverse Events
A - Fluoride Control B - Postive Control
Affected / at Risk (%) Affected / at Risk (%)
Total   0/55 (0.00%)   0/50 (0.00%) 
Show Other (Not Including Serious) Adverse Events Hide Other (Not Including Serious) Adverse Events
Frequency Threshold for Reporting Other Adverse Events 0%
A - Fluoride Control B - Postive Control
Affected / at Risk (%) Affected / at Risk (%)
Total   0/55 (0.00%)   0/50 (0.00%) 
Certain Agreements
Principal Investigators are NOT employed by the organization sponsoring the study.
There IS an agreement between Principal Investigators and the Sponsor (or its agents) that restricts the PI's rights to discuss or publish trial results after the trial is completed.
Results Point of Contact
Layout table for Results Point of Contact information
Name/Title: William De Vizio
Organization: Colgate Palmolive Co.
Phone: 732-878-7901
EMail: William_Devizio@colpal.com
Layout table for additonal information
Responsible Party: Willaim DeVizio/VP - Clinical Research, Colgate Palmolive
ClinicalTrials.gov Identifier: NCT00762619     History of Changes
Other Study ID Numbers: CRO-2007-IMPLANT-PS
First Submitted: September 26, 2008
First Posted: September 30, 2008
Results First Submitted: August 24, 2010
Results First Posted: January 25, 2011
Last Update Posted: January 25, 2011