32 of 117 for:
Dutasteride to Treat Spinal and Bulbar Muscular Atrophy (SBMA)
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
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ClinicalTrials.gov Identifier: NCT00303446
First Posted : March 16, 2006
Results First Posted : June 22, 2010
Last Update Posted : January 27, 2011
Information provided by:
National Institutes of Health Clinical Center (CC)
Allocation: Randomized; Intervention Model: Parallel Assignment; Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor); Primary Purpose: Treatment
Spinal and Bulbar Muscular Atrophy
All Principal Investigators ARE employed by the organization sponsoring the study.
Layout table for Results Point of Contact information
Kenneth Fischbeck, M.D.
National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH)
Rhodes LE, Freeman BK, Auh S, Kokkinis AD, La Pean A, Chen C, Lehky TJ, Shrader JA, Levy EW, Harris-Love M, Di Prospero NA, Fischbeck KH. Clinical features of spinal and bulbar muscular atrophy. Brain. 2009 Dec;132(Pt 12):3242-51. doi: 10.1093/brain/awp258.
Fernández-Rhodes LE, Kokkinis AD, White MJ, Watts CA, Auh S, Jeffries NO, Shrader JA, Lehky TJ, Li L, Ryder JE, Levy EW, Solomon BI, Harris-Love MO, La Pean A, Schindler AB, Chen C, Di Prospero NA, Fischbeck KH. Efficacy and safety of dutasteride in patients with spinal and bulbar muscular atrophy: a randomised placebo-controlled trial. Lancet Neurol. 2011 Feb;10(2):140-7. doi: 10.1016/S1474-4422(10)70321-5. Epub 2011 Jan 6.
Harris-Love MO, Fernandez-Rhodes L, Joe G, Shrader JA, Kokkinis A, La Pean Kirschner A, Auh S, Chen C, Li L, Levy E, Davenport TE, Di Prospero NA, Fischbeck KH. Assessing function and endurance in adults with spinal and bulbar muscular atrophy: validity of the adult myopathy assessment tool. Rehabil Res Pract. 2014;2014:873872. doi: 10.1155/2014/873872. Epub 2014 May 5.
Layout table for additonal information
Kenneth H. Fischbeck, M.D./National Institute of Neurological Disorders and Stroke, National Institutes of Health
History of Changes
Other Study ID Numbers:
06-N-0113 ( Other Identifier: NINDS IRB protocol number )
March 15, 2006
March 16, 2006
Results First Submitted:
December 9, 2009
Results First Posted:
June 22, 2010
Last Update Posted:
January 27, 2011