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CT Scores Predict Mortality in 2019-nCoV Pneumonia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04284046
Recruitment Status : Completed
First Posted : February 25, 2020
Last Update Posted : February 25, 2020
Sponsor:
Information provided by (Responsible Party):
Ruilan Wang, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Tracking Information
First Submitted Date February 22, 2020
First Posted Date February 25, 2020
Last Update Posted Date February 25, 2020
Actual Study Start Date January 31, 2020
Actual Primary Completion Date February 18, 2020   (Final data collection date for primary outcome measure)
Current Primary Outcome Measures
 (submitted: February 22, 2020)
7-day mortality [ Time Frame: 7-day ]
Original Primary Outcome Measures Same as current
Change History No Changes Posted
Current Secondary Outcome Measures Not Provided
Original Secondary Outcome Measures Not Provided
Current Other Pre-specified Outcome Measures Not Provided
Original Other Pre-specified Outcome Measures Not Provided
 
Descriptive Information
Brief Title CT Scores Predict Mortality in 2019-nCoV Pneumonia
Official Title CT Scores Predict Mortality in 2019-nCoV Pneumonia
Brief Summary While 2019-nCoV nucleic acid swab tests has high false positives rate, How to diagnose 2019-nCoV pneumonia and predict prognosis by CT is very important.In this retrospective single-center study, we consecutively included suspected 2019-nCoV pneumonia critical cases in the intensive care unit of Wuhan third hospital from January 31, 2020 to February 16, 2020. The cases were confirmed by real-time RT-PCR, and all patients were evaluated with CT, cutoff values were obtained according to the Yoden index, and were divided into high CT score group and low CT score group. Epidemiological, demographic, clinical, and laboratory data were collected.
Detailed Description Not Provided
Study Type Observational
Study Design Observational Model: Cohort
Time Perspective: Retrospective
Target Follow-Up Duration Not Provided
Biospecimen Not Provided
Sampling Method Non-Probability Sample
Study Population all patients suspected of 2019 novel coronavirus infection.
Condition CT Scores Predict Mortality in 2019-nCoV Pneumonia
Intervention Other: CT score
CT score = normal lung tissue (%) ×1 + GGO (%) ×2 + consolidation (%) ×3
Study Groups/Cohorts
  • High CT score
    Intervention: Other: CT score
  • Low CTscore
    Intervention: Other: CT score
Publications * Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruitment Information
Recruitment Status Completed
Actual Enrollment
 (submitted: February 22, 2020)
39
Original Actual Enrollment Same as current
Actual Study Completion Date February 18, 2020
Actual Primary Completion Date February 18, 2020   (Final data collection date for primary outcome measure)
Eligibility Criteria

Inclusion Criteria:

  • all patients suspected of 2019 novel coronavirus infection.

Exclusion Criteria:

  • patients' data are not available.
Sex/Gender
Sexes Eligible for Study: All
Ages Child, Adult, Older Adult
Accepts Healthy Volunteers No
Contacts Contact information is only displayed when the study is recruiting subjects
Listed Location Countries China
Removed Location Countries  
 
Administrative Information
NCT Number NCT04284046
Other Study ID Numbers CT2019-nCoV
Has Data Monitoring Committee Not Provided
U.S. FDA-regulated Product
Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
IPD Sharing Statement Not Provided
Responsible Party Ruilan Wang, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Study Sponsor Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Collaborators Not Provided
Investigators Not Provided
PRS Account Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Verification Date February 2020