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Collection of Blood and Bone Marrow From Patients With Aplastic Anemia for Analysis of Adhesion Molecules, Chemokines and Their Receptors

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT01680055
Recruitment Status : Withdrawn (No eligible patient was enrolled.)
First Posted : September 6, 2012
Last Update Posted : April 20, 2016
Sponsor:
Information provided by (Responsible Party):
Ming Hou, Shandong University

Tracking Information
First Submitted Date September 3, 2012
First Posted Date September 6, 2012
Last Update Posted Date April 20, 2016
Study Start Date February 2009
Primary Completion Date Not Provided
Current Primary Outcome Measures
 (submitted: September 3, 2012)
hematologic response [ Time Frame: 6 months following antithymocyte globulin plus cyclosporine treatment ]
hematologic response at 6 months following antithymocyte globulin plus cyclosporine treatment, defined as no longer meeting the criteria for severe aplastic anemia
Original Primary Outcome Measures Same as current
Change History
Current Secondary Outcome Measures Not Provided
Original Secondary Outcome Measures Not Provided
Current Other Pre-specified Outcome Measures Not Provided
Original Other Pre-specified Outcome Measures Not Provided
 
Descriptive Information
Brief Title Collection of Blood and Bone Marrow From Patients With Aplastic Anemia for Analysis of Adhesion Molecules, Chemokines and Their Receptors
Official Title Not Provided
Brief Summary This study is designed to collect bone marrow and/or peripheral blood cells and plasma, for the analysis of adhesion molecules, chemokines and their receptors from newly-diagnosed aplastic anemia patients, and patients treated with antithymocyte globulin plus cyclosporine
Detailed Description Not Provided
Study Type Observational
Study Design Observational Model: Case-Control
Time Perspective: Prospective
Target Follow-Up Duration Not Provided
Biospecimen Not Provided
Sampling Method Probability Sample
Study Population Patients With Aplastic Anemia
Condition
  • Aplastic Anemia
  • Healthy
Intervention Not Provided
Study Groups/Cohorts AA-ATG
Acquired Aplastic Anemia Patients Treated with Antithymocyte Globulin plus Cyclosporine
Publications * Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruitment Information
Recruitment Status Withdrawn
Actual Enrollment
 (submitted: April 18, 2016)
0
Original Estimated Enrollment
 (submitted: September 3, 2012)
70
Estimated Study Completion Date November 2012
Primary Completion Date Not Provided
Eligibility Criteria

Inclusion Criteria:

  • patients who fulfilled entry criteria of acquired aplastic anemia age range 16-70 years

Exclusion Criteria:

  • Patients complicated with diabetes, tumor, pregnancy, active infection, or connective tissue diseases, such as systemic lupus erythematosus.
Sex/Gender
Sexes Eligible for Study: All
Ages 16 Years to 70 Years   (Child, Adult, Older Adult)
Accepts Healthy Volunteers Yes
Contacts Contact information is only displayed when the study is recruiting subjects
Listed Location Countries China
Removed Location Countries  
 
Administrative Information
NCT Number NCT01680055
Other Study ID Numbers Aplastic Anemia 1
Has Data Monitoring Committee Not Provided
U.S. FDA-regulated Product Not Provided
IPD Sharing Statement Not Provided
Responsible Party Ming Hou, Shandong University
Study Sponsor Shandong University
Collaborators Not Provided
Investigators Not Provided
PRS Account Shandong University
Verification Date September 2012