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Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia

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ClinicalTrials.gov Identifier: NCT01160809
Recruitment Status : Completed
First Posted : July 12, 2010
Last Update Posted : July 12, 2010
Sponsor:
Collaborators:
Addis Ababa University
Columbia University
Coalition Against Malaria in Ethiopia
Information provided by:
Malaria Consortium, Ethiopia

Tracking Information
First Submitted Date  ICMJE July 8, 2010
First Posted Date  ICMJE July 12, 2010
Last Update Posted Date July 12, 2010
Study Start Date  ICMJE September 2008
Actual Primary Completion Date December 2008   (Final data collection date for primary outcome measure)
Current Primary Outcome Measures  ICMJE
 (submitted: July 9, 2010)
Malaria parasite (P. falciparum and/or P. vivax)through microscopic detection
The objective of the study is to investigate the impact of a combined use of mosquito repellent and LLINs in reducing malaria. The primary outcome of the study is detection of malaria parasites (P. falciparum and/or P. vivax) through examination of microscopic blood slides collected from finger-pricks.
Original Primary Outcome Measures  ICMJE Same as current
Change History No Changes Posted
Current Secondary Outcome Measures  ICMJE
 (submitted: July 9, 2010)
Household ownership and utilization of LLINs
Owneship and utilization of LLINs by household members during the night before the baseline survey
Original Secondary Outcome Measures  ICMJE Same as current
Current Other Pre-specified Outcome Measures Not Provided
Original Other Pre-specified Outcome Measures Not Provided
 
Descriptive Information
Brief Title  ICMJE Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia
Official Title  ICMJE Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Southern Ethiopia: a Cluster-randomized Controlled Trial
Brief Summary The combined use of a mosquito repellent and long lasting insecticidal nets (LLINs) by household members would result in a 40% reduction in malaria prevalence compared with households that only use LLINs.
Detailed Description It has been recognized that the use of malaria preventive measures in combination with LLINs could improve the effectiveness of nets in preventing the disease. This study examined the effect of a combined use of mosquito repellent (i.e., Buzz Off) and LLINs on malaria prevalence in an area of unstable and seasonal malaria transmission.
Study Type  ICMJE Interventional
Study Phase  ICMJE Phase 4
Study Design  ICMJE Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Condition  ICMJE
  • Malaria
  • Mosquito Repellent
  • Long Lasting Insecticidal Nets
Intervention  ICMJE Other: Mosquito repellent
Mosquito repellent (Buzz Off jelly) every evening applied to face, neck, hands and legs
Study Arms  ICMJE Experimental: Mosquito repellent and LLINs group vs. LLINs group only
This study is based on two population groups: 1) a group of households that use LLINs alone (control) and 2) a group of households that use both mosquito repellent and LLINs (repellent group).
Intervention: Other: Mosquito repellent
Publications * Deressa W, Yihdego YY, Kebede Z, Batisso E, Tekalegne A, Dagne GA. Effect of combining mosquito repellent and insecticide treated net on malaria prevalence in Southern Ethiopia: a cluster-randomised trial. Parasit Vectors. 2014 Mar 28;7:132. doi: 10.1186/1756-3305-7-132.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruitment Information
Recruitment Status  ICMJE Completed
Actual Enrollment  ICMJE
 (submitted: July 9, 2010)
6082
Original Actual Enrollment  ICMJE Same as current
Actual Study Completion Date  ICMJE January 2009
Actual Primary Completion Date December 2008   (Final data collection date for primary outcome measure)
Eligibility Criteria  ICMJE

Inclusion Criteria:

  • All volunteer household members

Exclusion Criteria:

  • Infants less than two months
  • Not in the study area
Sex/Gender  ICMJE
Sexes Eligible for Study: All
Ages  ICMJE Child, Adult, Older Adult
Accepts Healthy Volunteers  ICMJE Yes
Contacts  ICMJE Contact information is only displayed when the study is recruiting subjects
Listed Location Countries  ICMJE Ethiopia
Removed Location Countries  
 
Administrative Information
NCT Number  ICMJE NCT01160809
Other Study ID Numbers  ICMJE 0001
Has Data Monitoring Committee No
U.S. FDA-regulated Product Not Provided
IPD Sharing Statement  ICMJE Not Provided
Responsible Party Dr. Wakgari Deressa, School of Public Health, Addis Ababa University, Ethiopia
Study Sponsor  ICMJE Malaria Consortium, Ethiopia
Collaborators  ICMJE
  • Addis Ababa University
  • Columbia University
  • Coalition Against Malaria in Ethiopia
Investigators  ICMJE Not Provided
PRS Account Malaria Consortium, Ethiopia
Verification Date July 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP