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The Impact of Post-tetanic Count on Subsequent Train-of-four During Recovery From Rocuronium

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ClinicalTrials.gov Identifier: NCT01086176
Recruitment Status : Completed
First Posted : March 12, 2010
Last Update Posted : April 27, 2010
Sponsor:
Information provided by:
Maisonneuve-Rosemont Hospital

Tracking Information
First Submitted Date March 10, 2010
First Posted Date March 12, 2010
Last Update Posted Date April 27, 2010
Study Start Date March 2010
Actual Primary Completion Date April 2010   (Final data collection date for primary outcome measure)
Current Primary Outcome Measures
 (submitted: March 11, 2010)
The difference at 30 minutes after the post-tetanic count between the TOF% in both arms, we expect a difference of more than 10%
Original Primary Outcome Measures Same as current
Change History
Current Secondary Outcome Measures
 (submitted: March 11, 2010)
  • The difference at 30 minutes after the post-tetanic count on the T1% (of the calibrated T1) in both arms, we expect a difference of more than 10%
  • The difference of the slope of recuperation on TOF and T1% after a post-tetanic count vs the control arm that had no tetanic stimulation
Original Secondary Outcome Measures Same as current
Current Other Pre-specified Outcome Measures Not Provided
Original Other Pre-specified Outcome Measures Not Provided
 
Descriptive Information
Brief Title The Impact of Post-tetanic Count on Subsequent Train-of-four During Recovery From Rocuronium
Official Title Not Provided
Brief Summary The purpose of this study is to see how long does the effect of a post-tetanic facilitation last on subsequent train-of-four. The investigators hypothesis is that the effect last at least 30 minutes.
Detailed Description Not Provided
Study Type Observational
Study Design Observational Model: Case-Control
Time Perspective: Prospective
Target Follow-Up Duration Not Provided
Biospecimen Not Provided
Sampling Method Non-Probability Sample
Study Population Poeple having general anesthesia at HMR
Condition Post-tetanic Count on One Arm, the Other Arm is the Control
Intervention Device: NMT (a device that can do neurostimulation and can record the response on the stimulation by Datex)
on one side, we do a post-tetanic count, on the other side we don't, after, we do train-of-four on both sides and check the difference
Study Groups/Cohorts Patient-control
Intervention: Device: NMT (a device that can do neurostimulation and can record the response on the stimulation by Datex)
Publications * Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruitment Information
Recruitment Status Completed
Estimated Enrollment
 (submitted: March 11, 2010)
22
Original Estimated Enrollment Same as current
Actual Study Completion Date April 2010
Actual Primary Completion Date April 2010   (Final data collection date for primary outcome measure)
Eligibility Criteria

Inclusion Criteria:

  • Patient having general anesthesia in dorsal decubitus with both arm available for at least an hour and a half

Exclusion Criteria:

  • Age >75 or <18
  • Neuromuscular disease
  • difficult laryngoscopy predicted
  • Allergy to rocuronium
  • Malignant hyperthermia
  • Full stomach
  • Drugs the influence neuromuscular blockers
  • Decision of the clinician to exclude his patient
Sex/Gender
Sexes Eligible for Study: All
Ages 18 Years to 75 Years   (Adult, Older Adult)
Accepts Healthy Volunteers No
Contacts Contact information is only displayed when the study is recruiting subjects
Listed Location Countries Canada
Removed Location Countries  
 
Administrative Information
NCT Number NCT01086176
Other Study ID Numbers MaisonneuveRH-09092
Has Data Monitoring Committee Not Provided
U.S. FDA-regulated Product Not Provided
IPD Sharing Statement Not Provided
Responsible Party Louis-Philippe Fortier MD Msc, HMR
Study Sponsor Maisonneuve-Rosemont Hospital
Collaborators Not Provided
Investigators Not Provided
PRS Account Maisonneuve-Rosemont Hospital
Verification Date March 2010