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Omega-3 Supplementation Combined With Endurance Training Improve Running Economy in Recreational Runners.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04780451
Recruitment Status : Completed
First Posted : March 3, 2021
Last Update Posted : March 3, 2021
Sponsor:
Collaborators:
Medical University of Gdansk
University of Southampton
Information provided by (Responsible Party):
Gdansk University of Physical Education and Sport

Brief Summary:
Recreational male runners participated in 12 weeks training and omega-3 supplementation programme. Before starting and at the end of the 12-week cycle, the runners performed an increasing intensity treadmill test where oxygen uptake and VO2 peak were assessed.

Condition or disease Intervention/treatment Phase
Effect of Omega-3 Supplementation on Exercise Performance and Muscle Tissue Functions Dietary Supplement: Omega-3 supplementation in recreational runners Phase 3

Detailed Description:
40 healthy, recreational male runners participated in 12 weeks training and supplementation programme. The training protocol was built based on undulatory load manipulation 3:1, which was suggested to be effective to prevent overtraining and stress due to oscillations between volume/intensity. Throughout the study all participants took 4 identical-looking capsules per day (2 in the morning and 2 in the evening) containing either omega-3 fatty acids or medium chain triglycerides as placebo in total amount of 4g of fat per day. Before starting and at the end of the 12-week cycle, the runners performed an increasing intensity treadmill test where oxygen uptake and VO2 peak were assessed. Additionally, blood was collected to determine the concentrations of selected proteins (including eNOS, irisin, adiponectin) that may be associated with potential changes in participants' oxygen uptake during the treadmill test.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 40 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Investigator)
Primary Purpose: Basic Science
Official Title: 12 Weeks of Omega-3 Supplementation Combined With Endurance Training Improve Running Economy in Recreational Runners. The Potential Role of the Myokines-NO Pathway.
Actual Study Start Date : September 16, 2020
Actual Primary Completion Date : December 20, 2020
Actual Study Completion Date : March 2, 2021

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: Omega Dietary Supplement: Omega-3 supplementation in recreational runners
Male recreational runners participated in 12 weeks of endurance training combined with omega-3 fatty acids supplementation. Before starting and at the end of the 12-week cycle, the runners performed an increasing intensity treadmill test where oxygen uptake and VO2 peak were assessed.

Placebo Comparator: Placebo Dietary Supplement: Omega-3 supplementation in recreational runners
Male recreational runners participated in 12 weeks of endurance training combined with omega-3 fatty acids supplementation. Before starting and at the end of the 12-week cycle, the runners performed an increasing intensity treadmill test where oxygen uptake and VO2 peak were assessed.




Primary Outcome Measures :
  1. changes in oxygen consumption during running test [ Time Frame: between 10 and 25 minutes of the running test ]


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Ages Eligible for Study:   29 Years to 42 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • non smoking
  • no chronic diseases
  • no supplements and medicines
  • personal best in 10km run between 35 and 59 min at the turn of 2016 and 2020 y

Exclusion Criteria:

-


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04780451


Locations
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Poland
Gdansk University of Physical Education and Sport
Gdańsk, Poland, 80-336
Sponsors and Collaborators
Gdansk University of Physical Education and Sport
Medical University of Gdansk
University of Southampton
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Responsible Party: Gdansk University of Physical Education and Sport
ClinicalTrials.gov Identifier: NCT04780451    
Other Study ID Numbers: 2018/31/N/NZ7/02962
First Posted: March 3, 2021    Key Record Dates
Last Update Posted: March 3, 2021
Last Verified: February 2021

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Gdansk University of Physical Education and Sport:
omega-3
supplementation
endurance training
running