Diverting Ileostomy and Anal Functional Outcomes After Anus Preservation Surgery
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Layout table for eligibility information
Ages Eligible for Study:
18 Years to 75 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Middle and low rectal cancer patients
Necessary conditions: meet one of the following conditions
Difficult pelvis: narrow pelvis (diameter of ischial tuberosity <10 cm, diameter of ischial spine <12 cm) 13 or BMI≥30kg/m2 or tumor diameter≥5cm2.
To receive treatment before surgery: preoperative neoadjuvant radiotherapy or concurrent chemoradiation or ESD
The anastomosis is below the level of the levator ani muscle: such as ISR, TaTME surgery, etc.
Age: 18 to 75 years old, male or female;
Preoperative biopsy pathological diagnosis of rectal adenocarcinoma;
Received MRI evaluation before surgery, and the distance between the lower edge of the tumor and the anal edge is no more than 10cm;
The clinical stage is T1-3N0-2M0;
Undertake elective laparoscopic TME for colon-rectal or colon-anal anastomosis
ECOG score 0-2;
Heart, lung, liver, and kidney functions can tolerate surgery;
Patients and their families can understand and are willing to participate in this clinical study, and sign informed consent.
Past history of malignant colorectal tumors or recent diagnosis combined with other malignant tumors;
Patients with intestinal obstruction, intestinal perforation, intestinal bleeding, etc. who need emergency surgery;
Neighboring organs need to be combined with organ removal
ASA grade ≥ grade IV and/or ECOG physical status score> 2 points;
Those who have severe liver and kidney function, cardiopulmonary function, blood coagulation dysfunction, or combined with serious underlying diseases that cannot tolerate surgery;
Have a history of severe mental illness;
Pregnant or lactating women;
Those with a history of taking hormone drugs;
Patients with other clinical and laboratory conditions considered by the investigator should not participate in the trial.