Social Support and Enhanced Fear Extinction
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|ClinicalTrials.gov Identifier: NCT04565041|
Recruitment Status : Not yet recruiting
First Posted : September 25, 2020
Last Update Posted : September 25, 2020
University of California, Los Angeles researchers will recruit healthy participants and anxious participants (those diagnosed with social anxiety disorder) age 18-55 years old to participate in a study examining whether the ability of social support figure reminders to enhance the extinction of fear in healthy participants extends to those with anxiety disorders.
After being recruited from the UCLA community (healthy participants, n = 50) or referred by treatment providers at the Anxiety and Depression Research Center at UCLA (anxious participants, n = 50) and undergoing a telephone screening and in-person screening, 100 participants will be enrolled in the study. During the experiment, all participants will undergo the same procedures: undergoing a fear extinction procedure in which threatening cues--cues that predict electric shock--will be paired with either an image of a social support figure (provided by participants) or an image of a smiling stranger. These pairings will be presented repeatedly in the absence of shock in order for fear extinction to occur. Participants will return for a follow-up test to determine if fear extinction was successful.
|Condition or disease||Intervention/treatment||Phase|
|Fear Anxiety||Behavioral: Social Support||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||100 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Can Social Support Figures Enhance Fear Extinction in Patients With Social Anxiety?|
|Estimated Study Start Date :||January 2022|
|Estimated Primary Completion Date :||December 2022|
|Estimated Study Completion Date :||December 2022|
|Experimental: Social Support||
Behavioral: Social Support
Presence of an image of a social support figure (provided by participant) during a fear extinction procedure
- Fear response directly post-extinction [ Time Frame: within experimental session - directly post-extinction procedure ]presence of fear response as indicated by significantly higher galvanic skin response (GSR: an index of peripheral stress responding) to a previously learned fearful image (CS+) compared to a baseline comparator (CS-: never learned to be fearful).
- Fear response 24 hours post-extinction [ Time Frame: 24 hours following the completion of fear extinction procedures ]presence of fear response as indicated by significantly higher galvanic skin response (GSR: an index of peripheral stress responding) to a previously learned fearful image (CS+) compared to a baseline comparator (CS-: never learned to be fearful).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04565041
|Contact: Erica Hornstein, PhDemail@example.com|
|Contact: Naomi Eisenberger, PhD|
|United States, California|
|UCLA Department of Psychology|
|Los Angeles, California, United States, 90095-1563|