Long-term Follow up for Retinal Vascular Changes After Endoscopic Endonasal Pituitary Surgery.
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|ClinicalTrials.gov Identifier: NCT04546386|
Recruitment Status : Completed
First Posted : September 14, 2020
Last Update Posted : February 3, 2021
|Condition or disease||Intervention/treatment|
|Pituitary Adenoma||Procedure: Endoscopic endonasal pituitary surgery|
The role of the optical coherence tomography angiography to detect the changes in retinal vascular networks in patients after 48 hours and 1 year from the endoscopic endonasal surgery to remove an intra-suprasellar pituitary adenoma compressing the optic nerve.
The optical coherence tomography angiography allows a detailed and quantitative analysis of the retinal vascular networks and to follow their changes over time.
|Study Type :||Observational|
|Actual Enrollment :||14 participants|
|Official Title:||Retinal Vascular Changes After Endoscopic Endonasal Pituitary Surgery During One Year's Follow up, by Optical Coherence Tomography Angiography|
|Actual Study Start Date :||January 10, 2019|
|Actual Primary Completion Date :||March 10, 2020|
|Actual Study Completion Date :||March 25, 2020|
- Procedure: Endoscopic endonasal pituitary surgery
Surgical treatment consisted of an endoscopic endonasal approach using a rigid 0-degree endoscope, 18 cm in length and 4 mm in diameter
- Study of vessel density of the retinal vascular network in patients underwent endoscopic endonasal pituitary surgery, by optical coherence tomography angiography, during long-term follow up. [ Time Frame: one year ]To evaluate the changes in vessel density of the retinal vascular network 48 hours and 1 year after endoscopic endonasal pituitary surgery for the removal of an intra-suprasellar pituitary adenoma compressing the optic nerve, using optical coherence tomography angiography. The parameter analyzed by optical coherence tomography angiography was the vessel density of the retinal vascular network.
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04546386
|University of Naples "Federico II"|
|Naples, Italy, 80100|
|Principal Investigator:||Gilda Cennamo||Federico II University|