Cohort of Patients With Hepatocellular Carcinoma or Cholangiocarcinoma (CHC/CC)
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The main objective is to describe the evolution of patients treated for a primary malignant hepatobiliary tumor (hepatocellular carcinoma or cholangiocarcinoma) over the long course.
Condition or disease
The collection of data from patients with CHC and cholangiocarcinomas who are cancers with poor prognosis is a major challenge to improve patients'care (diagnosis, prognosis); facilitate the search for new therapeutic targets and the follow-up of clinical studies; and develop personalized treatments.
Hepatocellular carcinoma and Cholangiocarcinoma : Overall survival is defined as the survival 5 years after the inclusion.
Secondary Outcome Measures :
Overall survival [ Time Frame: 5 years ]
Hepatocellular carcinoma :Overall survival is defined as the survival after 5 years of inclusion.
Disease free survival [ Time Frame: 2 and 5 years ]
Cholangiocarcinoma : 2 and 5 years after surgical resection
Progression time under chemotherapy [ Time Frame: Time of progression under chemotherapy up to 5 years ]
Cholangiocarcinoma : Time of progression under chemotherapy is defined by the delay between the start of chemotherapy and tumor progression (appearance of a new lesion or increase in size of more than 30%)
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Layout table for eligibility information
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
All patients with hepatocellular carcinoma or cholangiocarcinoma treated in Saint-Antoine hospital
Inclusion Criteria :
Age ≥ 18 years olds
Medical care in Nephrology department since 2015
- Histologically and cytologically documented cholangiocarcinoma, regardless of the stage of the disease
Hepatocellular carcinoma at any stage of the disease, presenting the diagnostic criteria according to the diagnostic criteria of Barcelona : Tumor of more than 1 cm, developed on cirrhosis liver with arterial phase hyperenhancement and washout in the portal venous or delayed phases on CT and MRI