Staphylococcal Toxins in Atopic Dermatitis and Eczema Herpeticum (STADEH)
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|ClinicalTrials.gov Identifier: NCT04274348|
Recruitment Status : Not yet recruiting
First Posted : February 18, 2020
Last Update Posted : September 23, 2020
|Condition or disease||Intervention/treatment||Phase|
|Atopic Dermatitis Staphylococcus Aureus Bacterial Toxins Immune Response Cytokines T Cells Subsets||Other: Skin biopsies and blood samples||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||80 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Role of Staphylococci on Cytokine and T Cell Profiles in the Pathogenesis of Atopic Dermatitis and Eczema Herpeticum|
|Estimated Study Start Date :||October 2020|
|Estimated Primary Completion Date :||October 2023|
|Estimated Study Completion Date :||October 2023|
|Skin biopsies and blood samples||
Other: Skin biopsies and blood samples
Two skin biopsies and 30 ml of blood will be collected.
- Quantification of S. aureus colonization level and characterization of bacterial virulence profile in AD lesions. [ Time Frame: 2 hours (with consultation and sample) ]Biological data obtained from lesional skin will be compared with those of healthy skin.
- Determination of the inflammatory profile of skin and blood during AD. Definition of the seric cytokine signature characteristic of AD. Characterization of the phenotype and function of the lymphocytic infiltrate T during AD. [ Time Frame: 2 hours (with consultation and sample) ]Biological data obtained from lesional skin will be compared with those of healthy skin.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04274348
|Contact: Ewa HAINAUT, Dr||05 49 44 45 email@example.com|