Jaundice as Initial Presentation of Liver Hydatidosis (ICTEHIDA) (ICTEHIDA)
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|ClinicalTrials.gov Identifier: NCT04271176|
Recruitment Status : Active, not recruiting
First Posted : February 17, 2020
Last Update Posted : February 17, 2020
|Condition or disease|
|Hepatic Echinococcosis Jaundice|
Retrospective study of patients operated on for liver hydatidosis and whose initial symptom was obstructive jaundice Study period: January 2006 to September 2018
The preoperative diagnosis was based on abdominal ultrasound (US), CT scan or magnetic nuclear resonance
Surgical technique Precautions are taken to avoid the spillage of the parasite in the abdominal cavity. The peritoneal cavity is liberally protected with scolicidal agents. All patients have intraoperative ultrasound. Ultrasound is performed to locate the presence of any cysts which might not be seen by the preoperative imaging. Intraoperative ultrasound is also used to find out the relation of the cyst to the big vessels. Depending on the intraoperative findings, the location and size of the cyst will be considered the type of surgery to be performed. Radical surgery (closed and open total cystopericystectomy, or liver resection) or conservative surgery (partial cystopericystectomy, removal of the vesicles with external or internal drainage). When the cyst affects a total lobe and / or the main pedicles, a hepatectomy is performed.
The demographic data of the patients will be taken from their clinical histories. It included age, sex, medical history of hidatidosis, clinical findings, laboratory data, radiological findings, endoscopic treatment, surgical treatment.
The investigators will analyze postoperative mortality and morbidity. Complications' ranking according to the Clavien-Dindo score, 'severe complication' is defined as greater or equal to IIIa
Follow-up The follow-up of these patients will be performed with ultrasound or CT and hydatid serology. The minimum follow-up of the patients is six months. Relapse is defined as the appearance of new active liver cysts after the patient had undergone surgery.
|Study Type :||Observational|
|Estimated Enrollment :||35 participants|
|Official Title:||Liver Echinococcosis; Jaundice as Initial Presentation, Short and Long Term Results of Surgical Treatment|
|Actual Study Start Date :||January 1, 2009|
|Actual Primary Completion Date :||December 31, 2018|
|Estimated Study Completion Date :||April 30, 2020|
- Morbidity [ Time Frame: 90 days ]Postoperative morbidity after surgical treatment
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04271176
|Universidad de Extremadura- Facultad de Medicina|
|Badajoz, Spain, 06080|