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The Knowledge, Attitudes and Practices of Healthcare Workers on Drug Hypersensitivity Reactions in Children (KAPHWDHRC)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04252326
Recruitment Status : Active, not recruiting
First Posted : February 5, 2020
Last Update Posted : February 5, 2020
Sponsor:
Information provided by (Responsible Party):
Nazlı ERCAN, Saglik Bilimleri Universitesi

Brief Summary:
Adverse drug reactions are an important public health consern that affects physician prescriptions and practice. The responsibilities of healthcare professionals in monitoring, prevention, treatment and reporting of drug hypersensitivity reactions and drug allergies are essential for patient safety. Providing drug safety must be one of the main goals to be achieved for every member of our society. In our study, we planned to evaluate the knowledge, attitudes, and behaviors of healthcare workers in our country about drug hypersensitivity reactions in pediatric patients and to determine the risk factors that may affect them.

Condition or disease Intervention/treatment Phase
Adverse Drug Reactions Other: Survey Not Applicable

Detailed Description:
This study was carried out in a capital-located university hospital with a capacity of 1150 beds. Healthcare workers who are authorized to intervene in children (0-18 age group) including medical doctors, nurses and dentists were enrolled to study. In the evaluation of the knowledge, attitudes, and behaviors of the participants about drug hypersensitivity reactions in children, a study questionnaire was developed by pediatric allergy and immunology specialists and pediatric nurses by considering the other studies on the same subject.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 354 participants
Allocation: Non-Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
Primary Purpose: Health Services Research
Official Title: The Knowledge, Attitudes and Practices of Healthcare Workers on Drug Hypersensitivity Reactions in Children: A Tertiary Center Experience
Actual Study Start Date : February 1, 2019
Actual Primary Completion Date : June 1, 2019
Estimated Study Completion Date : February 1, 2020

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Active Comparator: Doctor
Knowledge, Attitudes and Practices on Drug Hypersensitivity Reactions in Children
Other: Survey
Doctors, Nurses and Dentists filled survey about adverse drug reractions

Active Comparator: Nurse
Knowledge, Attitudes and Practices on Drug Hypersensitivity Reactions in Children
Other: Survey
Doctors, Nurses and Dentists filled survey about adverse drug reractions

Active Comparator: Dentist
Knowledge, Attitudes and Practices on Drug Hypersensitivity Reactions in Children
Other: Survey
Doctors, Nurses and Dentists filled survey about adverse drug reractions




Primary Outcome Measures :
  1. we planned to evaluate the knowledge, attitudes, and behaviors of healthcare workers in our country about drug hypersensitivity reactions in pediatric patients [ Time Frame: It is planned to fill the questionnaire in 2 hours. ]
    1. The knowledge level domain, consisted of 24 questions including mechanism of drug hypersensitivity reactions, clinical findings, diagnosis and treatment. The answer format was 3 options (yes/no /don't know). A triple variable scale was used for knowledge level (0 to 2: 0, false; 1, true; 2, do not know).
    2. The attitude domain consisted of 5 questions including the effect of DHRs on the patient's quality of life and advanced training and current diagnostic tests for the needs in this regard. A five-point Likert-type scale was used for the questions to determine the level of agreement or disagreement (1 to 5; 1 strongly disagree; 2, disagree; 3, uncertain; 4, agree; 5, strongly agree)
    3. The practice domain consisted of 9 questions including taking history and practice in drug allergy and advanced training in DHR. A Likert-type scale was used to determine the level of practices (1 - 5: 1, never; 2, very rarely; 3, sometimes; 4, often; 5, always).

  2. we planned to evaluate the knowledge, attitudes, and behaviors of healthcare workers in our country about drug hypersensitivity reactions in pediatric patients [ Time Frame: It is planned to fill the questionnaire in 2 hours. ]

    The knowledge level domain, consisted of 24 questions including mechanism of drug hypersensitivity reactions, clinical findings, diagnosis and treatment. The answer format was 3 options (yes/no /don't know).

    2. The attitude domain consisted of 5 questions including the effect of DHRs on the patient's quality of life and advanced training and current diagnostic tests for the needs in this regard. A five-point Likert-type scale was used for the questions to determine the level of agreement or disagreement The practice domain consisted of 9 questions including taking history and practice in drug allergy and advanced training in DHR. A Likert-type scale was used to determine the level of practices



Secondary Outcome Measures :
  1. to determine the risk factors that may affect the knowledge, attitudes, and behaviors of healthcare workers in our country about drug hypersensitivity reactions in pediatric patient [ Time Frame: It is planned to fill the questionnaire in 2 hours. ]
    Participants'demographic questions regarding the age, gender, profession, duration in the profession, title and educational status of the participants may effect their surveys scores



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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

The study included healthcare workers including medical doctors, nurses and dentists who perform interventions on children (0-18 years of age).

Exclusion Criteria:

-


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04252326


Locations
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Turkey
Health Sciences University, Gülhane Training and Research Hospital, Gn. Dr. Tevfik Sağlam Cd No:11
Ankara, Etlik, Turkey, 06010
Sponsors and Collaborators
Saglik Bilimleri Universitesi
Investigators
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Principal Investigator: Nazlı Ercan, MD Saglik Bilimleri Universitesi
Publications of Results:
Other Publications:
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Responsible Party: Nazlı ERCAN, Pediatric Allergy and Immunology Specialist, Saglik Bilimleri Universitesi
ClinicalTrials.gov Identifier: NCT04252326    
Other Study ID Numbers: DrNazlı2020
First Posted: February 5, 2020    Key Record Dates
Last Update Posted: February 5, 2020
Last Verified: January 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Nazlı ERCAN, Saglik Bilimleri Universitesi:
Healthcare workers
Adverse drug reactions
Additional relevant MeSH terms:
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Hypersensitivity
Drug Hypersensitivity
Drug-Related Side Effects and Adverse Reactions
Immune System Diseases
Chemically-Induced Disorders