Effects of Recruitment Maneuver on Functional Residual Capacity
|ClinicalTrials.gov Identifier: NCT04208737|
Recruitment Status : Completed
First Posted : December 23, 2019
Last Update Posted : June 9, 2020
Recruitment maneuver is frequently used in daily anaesthesia routine to prevent athelectasia and ventilation perfusion mismatch. Especially pneumoperitoneum in laparoscopic surgeries affects the functional residual capacity (FRC) negatively. Recently, FRC can be measured at bedside in intensive care units.
The lack of studies evaluating FRC measurements peroperatively and how recruitment maneuvers affect it, attract attention.
|Condition or disease||Intervention/treatment||Phase|
|Anesthesia Surgery Atelectasis||Procedure: recruitment maneuver||Not Applicable|
An ICU-ventilator capable to measure the FRC will be used for the mechanical ventilation in patients undergıoing laparoscopic surgery, where anaesthesia maintenance will be achieved with TIVA.
FRC will be measured in different steps of the operation. In the study group, a recruitment manover will be applied to evaluate its effects on FRC.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||50 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Outcomes Assessor)|
|Official Title:||Comparing Effects of Recruitment Maneuver on Functional Residual Capacity in Patients Undergo Laparoscopic Surgery : A Randomized Prospective Study.|
|Actual Study Start Date :||December 23, 2019|
|Actual Primary Completion Date :||May 1, 2020|
|Actual Study Completion Date :||June 1, 2020|
No Intervention: control group
3 FRC measurements will be perforemed, whereby : First measurement; after aneshesia induction and intubation. Second measurement; after pneumoperitoneum Third measurement; end of the operation
After the operation,Postoperative Room Air Test (RAT) will be applied.
Experimental: study group
5 FRC measurements will be performed We will apply recruitment maneuver two times to patients with 30cmH2O pressure for 15 seconds .
First Recruitment maneuver will be applied after the fşrst measurement of FRC following intubation Second Recuitment maneuver will be applied at the end of operation
First FRC measurement after anesthesia induction and intubation. Second FRC measurement after first recruitment maneuver Third FRC measurement; after pneumoperitoneum Fourth FRC measurement before second recruitment maneuver Fifth FRC measurement after second recruitment maneuver and at the end of operation
Procedure: recruitment maneuver
30 cmH2O pressure 15 seconds
- Comparison of FRC measurements at beginning and end of anesthesia [ Time Frame: within max 5 minutes after the intubation and with max 5 minutes before the extubation ]First FRC will be measured after ; the last FRC will be measure bedore the extubation
- Positive room air test [ Time Frame: in recovery room 30 minutes after operation ]in recovery room when patient modified aldrete score ≥ 9 patient SPO2 when breathing in room air If patients' spo2 value ≤ 96%, named as room air test positive
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04208737
|Istanbul, Turkey, 34069|
|Istanbul University, Department of Anesthesiology|
|Istanbul, Turkey, 34093|
|Principal Investigator:||Elif Aygun, MD||Istanbul University|