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Effect of Different Fluid Ingestion Rate on Post-exercise Rehydration

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04155372
Recruitment Status : Not yet recruiting
First Posted : November 7, 2019
Last Update Posted : November 8, 2019
Sponsor:
Collaborator:
Kaohsiung Medical University
Information provided by (Responsible Party):
LIN, JIAN-YU, Kaohsiung Veterans General Hospital.

Brief Summary:
The purpose of the present study is to investigate the effect of different rate of fluid consumption on post-exercise rehydration.

Condition or disease Intervention/treatment Phase
Dehydration Procedure: Different Fluid Ingestion Rate Not Applicable

Detailed Description:
The body water deficits equivalent to 2% body mass might impair performance. Due to high exercise intensity, thermal environment, or rule limitation, athletes often in dehydration status post-exercise. Thus, how to rehydrate effectively to prepare the next game is important. The participants arrived to the lab euhydrated and were dehydrated to 2% of body weight by running. After a rest, they will ingest sports drink in a volume equivalent to 150% of BW loss in 30 min, 60 min, or 90 min. Urine and blood sample will be collected to evaluate hydration status.

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 30 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effect of Different Fluid Ingestion Rate on Post-exercise Rehydration
Estimated Study Start Date : December 2019
Estimated Primary Completion Date : July 2020
Estimated Study Completion Date : August 2020

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: 30min
The participants arrived to the trials euhydrated and were dehydrated to 2% of body weight (BW) by running. After a rest, they ingested sports drink in a volume equivalent to 150% of BW loss in 30 min.
Procedure: Different Fluid Ingestion Rate
The participants ingested sports drink in a volume equivalent to 150% of BW loss, in 30 min, 60 min, or 90min.

Experimental: 60min
The participants arrived to the trials euhydrated and were dehydrated to 2% of body weight (BW) by running. After a rest, they ingested sports drink in a volume equivalent to 150% of BW loss in 60 min.
Procedure: Different Fluid Ingestion Rate
The participants ingested sports drink in a volume equivalent to 150% of BW loss, in 30 min, 60 min, or 90min.

Experimental: 90min
The participants arrived to the trials euhydrated and were dehydrated to 2% of body weight (BW) by running. After a rest, they ingested sports drink in a volume equivalent to 150% of BW loss in 90 min.
Procedure: Different Fluid Ingestion Rate
The participants ingested sports drink in a volume equivalent to 150% of BW loss, in 30 min, 60 min, or 90min.




Primary Outcome Measures :
  1. specific gravity of urine(SG) [ Time Frame: Change from baseline outcome measure at dehydration and 1st and 2nd hour in recovery period ]
    dehydration: >= 1.020

  2. Osmolality(Urine) [ Time Frame: Change from baseline outcome measure at dehydration and 1st and 2nd hour in recovery period ]
    dehydration: >= 700 mosm/kg

  3. Osmolality(Blood) [ Time Frame: Change from baseline outcome measure at dehydration and 1st and 2nd hour in recovery period ]
    dehydration: >= 290 mosm/kg

  4. Vasopressin [ Time Frame: Change from baseline outcome measure at dehydration and 1st and 2nd hour in recovery period ]
    Vasopressin, also called antidiuretic hormone (ADH), arginine vasopressin (AVP) or argipressin, is a hormone synthesized as a peptide prohormone in neurons in the hypothalamus, and is converted to AVP. Increasing the water reabsorption and excretion of more concentrated urine.

  5. sodium(blood) [ Time Frame: Change from baseline outcome measure at dehydration and 1st and 2nd hour in recovery period ]
    135~145mEq/L

  6. Body weight change [ Time Frame: Change from baseline outcome measure at dehydration and 1st and 2nd hour in recovery period ]
    measure body weight at baseline, dehydration, 1st and 2nd hour in recovery period in kg



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Ages Eligible for Study:   20 Years to 35 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • 20~35 years old male
  • Exercise 150 min per week
  • Without chronic disease or gastrointestinal surgery

Exclusion Criteria:

  • Injury
  • Answer "Yes" in part 1 of the Physical Activity Readiness Questionnaire(PAR-Q+)
  • Participate in other studies within one month

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04155372


Contacts
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Contact: JIAN-YU LIN 886-7-342-2121 ext 8248 linchainyu0822@gmail.com

Sponsors and Collaborators
Kaohsiung Veterans General Hospital.
Kaohsiung Medical University
Investigators
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Principal Investigator: JIAN-YU LIN Kaohsiung Veterans General Hospital.
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Responsible Party: LIN, JIAN-YU, Principal Investigator, Kaohsiung Veterans General Hospital.
ClinicalTrials.gov Identifier: NCT04155372    
Other Study ID Numbers: VGHKS19-CT7-08
First Posted: November 7, 2019    Key Record Dates
Last Update Posted: November 8, 2019
Last Verified: November 2019

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by LIN, JIAN-YU, Kaohsiung Veterans General Hospital.:
sports nutrition
dehydration
sports medicine
rehydration
ingestion rate
Additional relevant MeSH terms:
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Dehydration
Water-Electrolyte Imbalance
Metabolic Diseases
Pathologic Processes