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Patient Portal Reminder/Recall for Influenza Vaccination in a Health System- RCT 2

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04110314
Recruitment Status : Completed
First Posted : October 1, 2019
Last Update Posted : October 30, 2020
Sponsor:
Information provided by (Responsible Party):
Peter G Szilagyi, MD MPH, University of California, Los Angeles

Brief Summary:

This trial is taking place in Los Angeles, CA among patients from primary care practices within the UCLA Health System.

Despite the Advisory Committee on Immunization Practices (ACIP) recommendation in 2010 that all people above 6 months of age should receive an annual flu vaccine, vaccination rates remain low. The investigators will assess the effectiveness of message-framing (gain-framed, loss-framed messages, no messages), as well as the effectiveness of a pre-commitment prompt (pre-commitment prompt, no prompt) asking about a patient's intention to get the influenza vaccination, using a 3 x 2 factorial design.


Condition or disease Intervention/treatment Phase
Influenza Respiratory Tract Infections Behavioral: Portal Reminders for Influenza Vaccination: Gain-framed Behavioral: Portal Reminders for Influenza Vaccination: Loss-framed Behavioral: Pre-commitment prompt Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 430636 participants
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single (Participant)
Primary Purpose: Health Services Research
Official Title: Improving Influenza Vaccination Delivery Across a Health System by the Electronic Health Records Patient Portal- RCT #2
Actual Study Start Date : October 18, 2019
Actual Primary Completion Date : April 1, 2020
Actual Study Completion Date : April 1, 2020

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Flu Flu Shot

Arm Intervention/treatment
Active Comparator: Gain-framed portal reminders + Pre-commitment Prompts
Participants receive gain-framed reminder/recall messages regarding influenza vaccination via the patient portal and a pre-commitment prompt asking if they plan to receive the influenza vaccine in the upcoming season
Behavioral: Portal Reminders for Influenza Vaccination: Gain-framed
Patients receive gain-framed reminder/recall messages via the patient portal to get an influenza vaccination.

Behavioral: Pre-commitment prompt
Patients receive a pre-commitment prompt asking about their intention to get an influenza vaccination

Active Comparator: Gain-framed portal reminders + No pre-commitment prompt
Participants receive gain-framed reminder/recall messages regarding influenza vaccination via the patient portal and no pre-commitment prompt asking if they plan to receive the influenza vaccine in the upcoming season
Behavioral: Portal Reminders for Influenza Vaccination: Gain-framed
Patients receive gain-framed reminder/recall messages via the patient portal to get an influenza vaccination.

Active Comparator: Loss-framed portal reminders + Pre-commitment prompt
Participants receive loss-framed reminder/recall messages regarding influenza vaccination via the patient portal and a pre-commitment prompt asking if they plan to receive the influenza vaccine in the upcoming season
Behavioral: Portal Reminders for Influenza Vaccination: Loss-framed
Patients receive loss-framed reminder/recall messages via the patient portal to get an influenza vaccination.

Behavioral: Pre-commitment prompt
Patients receive a pre-commitment prompt asking about their intention to get an influenza vaccination

Active Comparator: Loss-framed portal reminders + No pre-commitment prompt
Participants receive loss-framed reminder/recall messages regarding influenza vaccination via the patient portal and a no pre-commitment prompt asking if they plan to receive the influenza vaccine in the upcoming season
Behavioral: Portal Reminders for Influenza Vaccination: Loss-framed
Patients receive loss-framed reminder/recall messages via the patient portal to get an influenza vaccination.

Active Comparator: No portal reminder + Pre-commitment prompt
Participants do not receive any reminder/recall messages regarding influenza vaccination via the patient portal but do receive a pre-commitment prompt asking if they plan to receive the influenza vaccine in the upcoming season
Behavioral: Pre-commitment prompt
Patients receive a pre-commitment prompt asking about their intention to get an influenza vaccination

No Intervention: No portal reminders + No pre-commitment prompt
Participants do not receive any reminder/recall messages regarding influenza vaccination via the patient portal and do not receive a pre-commitment prompt asking if they plan to receive the influenza vaccine in the upcoming season



Primary Outcome Measures :
  1. Receipt of the annual influenza vaccine among index patients. [ Time Frame: 6 months ]

    Receipt of the annual influenza vaccination (between 10/2/19 - 4/1/20) among index patients. Outcomes will be assessed via vaccine data extraction from the electronic health record and external claims and pharmacy data.

    Index patients will be randomly selected individuals within an included household, eligible for the following groups (age <18, 18-64 non-diabetic, 65+ non-diabetic, and 18+ diabetic). One index patient per group may be selected from each household.

    The index patients must also be an active UCLA Health MyChart user (>= 1 login over the last 12 months from 8/1/19, excluding activity on the user's initial profile activation date). Individuals not affiliated with any primary care practice will be excluded from the primary analysis.



Secondary Outcome Measures :
  1. Receipt of annual influenza vaccine among all included patients in identified households. [ Time Frame: 6 months ]

    Receipt of annual influenza vaccine (between 10/2/19 - 4/1/20) among all included patients in identified households. Outcomes will be assessed via vaccine data extraction from the electronic health record and external claims and pharmacy data.

    All enrolled study participants, excluding unaffiliated patients and infants < 4 months, will be included in this secondary analysis.




Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


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Ages Eligible for Study:   4 Months and older   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • A patient within the UCLA Health System identified as a primary care patient per an internal algorithm,

Exclusion Criteria:

  • A patient within the UCLA Health System not identified as a primary care patient per an internal algorithm

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04110314


Locations
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United States, California
University of California LA
Los Angeles, California, United States, 99095
Sponsors and Collaborators
University of California, Los Angeles
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Responsible Party: Peter G Szilagyi, MD MPH, Principal Investigator, University of California, Los Angeles
ClinicalTrials.gov Identifier: NCT04110314    
Other Study ID Numbers: R01AI135029 ( U.S. NIH Grant/Contract )
First Posted: October 1, 2019    Key Record Dates
Last Update Posted: October 30, 2020
Last Verified: October 2020

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Peter G Szilagyi, MD MPH, University of California, Los Angeles:
Vaccination
Reminder recall
Patient Portal
Additional relevant MeSH terms:
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Respiratory Tract Infections
Influenza, Human
Orthomyxoviridae Infections
RNA Virus Infections
Virus Diseases
Respiratory Tract Diseases
Infection
Vaccines
Immunologic Factors
Physiological Effects of Drugs