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Infrared Thermography for the Diagnosis of Musculoskeletal Pain

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT04097249
Recruitment Status : Completed
First Posted : September 20, 2019
Last Update Posted : September 20, 2019
Information provided by (Responsible Party):
Universidad San Jorge

Brief Summary:
This study sought to evaluate the vasomotor response in the pain referral area of healthy individuals, performing the same procedure with and without the experience of delayed onset muscle soreness.

Condition or disease
Healthy Pain Temperature Change, Body

Detailed Description:
Validity of infrared thermography for properly diagnosing musculoskeletal pain and their clinical applicability is lacking. This study investigates temperature changes on the upper extremity before and after a suprathreshold stimulation (painful stimulus) with a digital algometer over the infraspinatus muscle. The same procedure is performed in two consecutive days, 24 hours apart (Day-1 and Day-2). At the end of Day-1, an eccentric exercise is performed in order to to induce delayed onset muscle soreness on the external rotators of the shoulder.

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Study Type : Observational [Patient Registry]
Actual Enrollment : 20 participants
Observational Model: Case-Crossover
Time Perspective: Cross-Sectional
Target Follow-Up Duration: 2 Days
Official Title: The Contribution and Validity of Infrared Thermography in the Diagnosis of Musculoskeletal Pain
Actual Study Start Date : October 1, 2015
Actual Primary Completion Date : April 29, 2016
Actual Study Completion Date : April 30, 2016

Healthy subjects
Participants free from any pain specific to the upper limb, chronic pain or other disease.

Primary Outcome Measures :
  1. Changes in temperature of pixels on the upper extremity: infrared thermography [ Time Frame: Day-1 (baseline assessment, pre exercise before painful stimulus), Day-1 (baseline assessment, pre exercise after painful stimulus), Day-2 (24 hours post-exercise before painful stimulus), Day-2 (24 hours post-exercise after painful stimulus) ]
    A thermography image of the upper extremity of the body will be taken on both days of assessment before and after applying a painful stimulus. Changes in colour pixels will be analysed to determine temperature changes.

Secondary Outcome Measures :
  1. Changes in Pressure Pain Thresholds: pressure algometry [ Time Frame: Day-1 (baseline assessment, pre exercise before painful stimulus), Day-2 (24 hours post-exercise before painful stimulus) ]
    Changes in pressure pain thresholds will be determined with pressure algometry over the infraspinatus muscle. Pressure Pain Threshold is defined as the exact time point where the pressure is first being perceived as painful.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Participants with no acute pain, chronic pain or other medical disorders relevant to this study.

Inclusion Criteria:

  • Being healthy and free from any pain specific to the upper limbs and/or in general.

Exclusion Criteria:

  • Previous history of chronic pain.
  • Any systemic diseases or regional pathology which can interfere with the outcome measures.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT04097249

Sponsors and Collaborators
Universidad San Jorge
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Study Director: Pablo Herrero, PhD Universidad San Jorge
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Responsible Party: Universidad San Jorge Identifier: NCT04097249    
Other Study ID Numbers: P15/2015
First Posted: September 20, 2019    Key Record Dates
Last Update Posted: September 20, 2019
Last Verified: September 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Plan Description: There are currently no plan on sharing data from this study with other researchers.

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Universidad San Jorge:
Musculoskeletal pain
Delayed Onset Muscle Soreness
Pain sensitivity
Infrared thermography
Referred pain
Additional relevant MeSH terms:
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Musculoskeletal Pain
Body Temperature Changes
Muscular Diseases
Musculoskeletal Diseases
Neurologic Manifestations