Ultrafine Particles and Fetal Contamination (FOETOPUF)
|ClinicalTrials.gov Identifier: NCT04068389|
Recruitment Status : Completed
First Posted : August 28, 2019
Last Update Posted : August 28, 2019
|Condition or disease||Intervention/treatment|
|Lung; Premature Pollution; Exposure||Procedure: Pulmonary Tissue Collection|
Epidemiological studies have demonstrated the harmful effects of particulate air pollution on the progress of pregnancy and postnatal health.
Experimental studies have suggested the transplacental passage of asbestos fibers, but despite the strong growth in the use and production of fine and ultrafine particles, no study has examined the permeability of the placenta to these compounds or the exposures fetuses that may result.
The objective of this study is to evaluate the transplacental passage of fine and ultrafine particles (nanoparticles) inhaled by the mother.
|Study Type :||Observational|
|Actual Enrollment :||62 participants|
|Official Title:||Study of the Permeability of Atmospheric Particles Placenta (Fine and Ultrafine Particles): Analysis of Fetal Retention|
|Actual Study Start Date :||December 22, 2009|
|Actual Primary Completion Date :||November 9, 2012|
|Actual Study Completion Date :||November 9, 2012|
- Procedure: Pulmonary Tissue Collection
Pulmonary Tissue Collection
- Presence of fine particles in fetal lung samples yes/no [ Time Frame: At the screening ]Analysis in electron microscopy
Biospecimen Retention: Samples Without DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04068389
|Principal Investigator:||Olivia OCHRYMCZUK, Dr||University Hospital, Bordeaux|