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The Influences of Dry Eye Disease on Optical Quality

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04043949
Recruitment Status : Completed
First Posted : August 2, 2019
Last Update Posted : August 2, 2019
Sponsor:
Information provided by (Responsible Party):
Peking University Third Hospital

Brief Summary:
DED could result in visual disturbance and damage optical quality. We aimed to evaluate the influences of dry eye disease (DED) on optical quality and their correlations.

Condition or disease
Dry Eye Vision; Disturbance, Hysterical

Detailed Description:
This study is aimed at evaluating changes of optical quality in dry eye patients with superficial punctate keratopathy after being treated by artificial lubricant and anti-inflammatory eye drops.

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Study Type : Observational
Actual Enrollment : 90 participants
Observational Model: Case-Control
Time Perspective: Prospective
Official Title: The Influences of Dry Eye Disease on Optical Quality
Actual Study Start Date : July 1, 2017
Actual Primary Completion Date : July 1, 2018
Actual Study Completion Date : July 1, 2018

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Eye Diseases

Group/Cohort
Normal
healthy subjects
Dry eye group
patients with dry eye
Dry eye after treatment
patients with dry eye after treatment



Primary Outcome Measures :
  1. The severity of DED influenced the optical quality of dry eye patients [ Time Frame: 2017.7-2019.7 ]
    The optical quality of dry eye patients

  2. High order abberations [ Time Frame: 2017.7-2019.7 ]
    cornela high order abberations of patients



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Aged between 18-65 years old.
Criteria

Inclusion Criteria:

  1. patients were diagnosed as dry eye according to the criteria provided by the Dry Eye Workshop (DEWS)
  2. positive corneal fluorescein staining (CFS)
  3. best-corrected distance visual acuity better than 20/20.

Exclusion Criteria:

History of ocular surgeries, contact lens wear, meibomian gland dysfunction, and any type of corneal scarring such as dystrophies or infections.


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04043949


Locations
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China, Beijing
Peking University Third Hospital
Beijing, Beijing, China, 100191
Sponsors and Collaborators
Peking University Third Hospital
Investigators
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Study Chair: Hong Qi, MD,Phd Peking University Third Hospital

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Responsible Party: Peking University Third Hospital
ClinicalTrials.gov Identifier: NCT04043949    
Other Study ID Numbers: DEDOQ
First Posted: August 2, 2019    Key Record Dates
Last Update Posted: August 2, 2019
Last Verified: December 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Keratoconjunctivitis Sicca
Dry Eye Syndromes
Eye Diseases
Keratoconjunctivitis
Conjunctivitis
Conjunctival Diseases
Keratitis
Corneal Diseases
Lacrimal Apparatus Diseases