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Correlation Between External Jugular Venous and Central Venous Blood Oxygen Saturation in Patient Under General Anesthesia

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ClinicalTrials.gov Identifier: NCT04017182
Recruitment Status : Not yet recruiting
First Posted : July 12, 2019
Last Update Posted : July 12, 2019
Sponsor:
Information provided by (Responsible Party):
Thanist Pravitharangul, Ramathibodi Hospital

Brief Summary:
After installation of central venous catheter in patients under general anesthesia, paired sample of central venous blood and right external jugular venous blood will be collected and send to central laboratory for blood gas analysis. Correlation between central venous blood and right external jugular venous blood oxygen saturation will be determined as primary outcome.

Condition or disease
Central Venous Oxygen Saturation

Detailed Description:
All patients undergoing surgery under general anesthesia and superior vena cava central venous catheter installation anticipated are eligible. Immediate after central venous installation, 1 ml of venous blood sample is taken from right external jugular vein and central venous catheter and send for blood gas analysis. Correlation between central venous blood and right external jugular venous blood oxygen saturation and partial pressure of carbon dioxide will be determined and prediction equation for central venous saturation is created.

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Study Type : Observational
Estimated Enrollment : 50 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Correlation Between External Jugular Venous and Central Venous Blood Oxygen Saturation in Patient Under General Anesthesia
Estimated Study Start Date : December 2019
Estimated Primary Completion Date : June 2020
Estimated Study Completion Date : July 2020

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Oxygen Therapy




Primary Outcome Measures :
  1. Correlation of venous oxygen saturation [ Time Frame: 1 hour ]
    Correlation of venous oxygen saturation between external jugular vein and superior vena cava


Secondary Outcome Measures :
  1. Correlation of venous partial pressure of carbon dioxide [ Time Frame: 1 hour ]
    Correlation of venous partial pressure of carbon dioxide between external jugular vein and superior vena cava

  2. Relationship between superior vena cava central venous and external jugular venous oxygen saturation [ Time Frame: 1 hour ]
    Linear regression to determine prediction equation between superior vena cava oxygen saturation and external jugular vein oxygen saturation



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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Adult surgical patients undergoing surgery under general anesthesia in institutional operating theaters with superior vena cava central venous catheter installation anticipated.
Criteria

Inclusion Criteria:

  • Surgical patients undergoing surgery under general anesthesia
  • Internal jugular central venous catheter anticipated
  • Not receiving inotropic or vasopressor drug
  • Systolic blood pressure not less than 90 mmHg
  • Anticipated right external jugular venous sampling time less than 5 minutes

Exclusion Criteria:

  • No jugular central venous catheter installation or other route selected
  • Duration of paired sample collection more than 10 minutes

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04017182


Contacts
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Contact: Thanist Pravitharangul, MD 66866633694 thnst_yu@msn.com
Contact: Cherdkiat Karnjanarachata, MD 66855774747 chird_na@yahoo.com

Locations
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Thailand
Department of Anesthesiology, Ramathibodi Hospital
Bankok, Bangkok, Thailand, 10400
Sponsors and Collaborators
Ramathibodi Hospital

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Responsible Party: Thanist Pravitharangul, Principal investigator, Ramathibodi Hospital
ClinicalTrials.gov Identifier: NCT04017182     History of Changes
Other Study ID Numbers: 04072019
First Posted: July 12, 2019    Key Record Dates
Last Update Posted: July 12, 2019
Last Verified: July 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Thanist Pravitharangul, Ramathibodi Hospital:
central venous oxygen saturation
external jugular venous oxygen saturation
central venous catheter
external jugular vein
internal jugular vein
superior vena cava oxygen saturation
Additional relevant MeSH terms:
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Anesthetics
Central Nervous System Depressants
Physiological Effects of Drugs